ID | 63967 |
フルテキストURL | |
著者 |
Asada, Takahiro
Department of Neuropsychiatry, Okayama University Hospital
Takenoshita, Shintaro
Department of Neuropsychiatry, Okayama University Hospital
ORCID
Senda, Mayuko
Department of Neuropsychiatry, Okayama University Hospital
Yamamoto, Koichiro
Department of General Medicine, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
Sasaki, Ryo
Department of Neurology, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
Otsuka, Fumio
Department of General Medicine, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
ORCID
Kaken ID
publons
researchmap
Terada, Seishi
Department of Neuropsychiatry, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
Kaken ID
publons
researchmap
Yamada, Norihito
Department of Neuropsychiatry, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
ORCID
Kaken ID
researchmap
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抄録 | Background Autoimmune hypothalamitis is a very rare neuroendocrine disorder that causes central diabetes insipidus, headache, visual impairment, and sometimes cognitive impairment. Autoimmune hypothalamitis may occur in association with autoimmune hypophysitis, including lymphocytic hypophysitis, or in isolation. It is not known whether autoimmune hypothalamitis and autoimmune hypophysitis are consecutive diseases. Case presentation A 52-year-old woman developed autoimmune hypothalamitis 7 years after developing central diabetes insipidus due to lymphocytic hypophysitis, resulting in severe memory impairment. High-dose intravenous methylprednisolone therapy improved her cognitive function and decreased the size of the lesion. Conclusion This case presented a unique clinical course, with a long period of time between the onset of autoimmune hypopituitaritis and the development of autoimmune hypothalamitis.
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キーワード | Lymphocytic hypophysitis
Autoimmune hypophysitis
Autoimmune hypothalamitis
Cognitive dysfunction
Memory impairment
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発行日 | 2022-09-29
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出版物タイトル |
BMC Neurology
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巻 | 22巻
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号 | 1号
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出版者 | BMC
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開始ページ | 371
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ISSN | 1471-2377
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資料タイプ |
学術雑誌論文
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言語 |
英語
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OAI-PMH Set |
岡山大学
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著作権者 | © The Author(s) 2022.
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論文のバージョン | publisher
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PubMed ID | |
DOI | |
Web of Science KeyUT | |
関連URL | isVersionOf https://doi.org/10.1186/s12883-022-02891-z
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ライセンス | http://creativecommons.org/licenses/by/4.0/
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助成機関名 |
Zikei Institute of Psychiatry
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