ID | 64971 |
フルテキストURL | |
著者 |
Kikuchi, Tatsuya
Department of Gastroenterology, Okayama University Hospital
Tanaka, Yoshinori
Department of Hematology, Hiroshima City Hiroshima Citizens Hospital
Ichimura, Kouichi
Department of Pathology, Hiroshima City Hiroshima Citizens Hospital
Okada, Hiroyuki
Department of Gastroenterology, Okayama University Hospital
Kaken ID
publons
researchmap
Okamoto, Ryoichi
Department of Internal Medicine, Hiroshima City Hiroshima Citizens Hospital
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抄録 | BackgroundPatients with Hodgkin lymphoma exhibit various clinical presentations. Needle biopsy of the lymph nodes is a minimally invasive procedure and a useful diagnostic method for malignant lymphomas. However, at times it is difficult to differentiate malignant lymphomas from reactive lymph node changes using a small amount of biopsy material.Case presentationA 77-year-old Japanese man was referred to the emergency department of our hospital owing to high fever and disturbance of consciousness. We diagnosed sepsis due to an acute biliary tract infection because he presented with Charcot's triad-fever, jaundice, and right-sided abdominal pain. However, he did not respond well to antimicrobial therapy and his high fever persisted. Considering the swelling of the right cervical, mediastinal, and intraperitoneal lymph nodes and splenomegaly detected on computed tomography, a differential diagnosis of malignant lymphoma was needed. Hence, we performed a needle biopsy of the right cervical lymph node; however, the amount of sample obtained was insufficient in establishing a definitive diagnosis of malignant lymphoma. Furthermore, during hospitalization, the patient developed thrombocytopenia, anasarca, and renal insufficiency. These symptoms seemed to be the typical signs of the thrombocytopenia, anasarca, fever, reticulin fibrosis or renal insufficiency, and organomegaly syndrome. Next, an external incisional mass biopsy of the right cervical lymph node was performed, which helped identify Hodgkin and Reed-Sternberg cells. Collectively, we established a definitive diagnosis of Hodgkin lymphoma with lymphoma-associated hemophagocytic syndrome.ConclusionsThis case highlights the importance of performing an external incisional mass biopsy of the lymph nodes for the early diagnosis and treatment, if malignant lymphoma is strongly suspected.
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キーワード | Hodgkin lymphoma
Hemophagocytic syndrome
TAFRO syndrome
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発行日 | 2023-02-21
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出版物タイトル |
Journal of Medical Case Reports
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巻 | 17巻
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号 | 1号
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出版者 | BMC
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開始ページ | 61
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ISSN | 1752-1947
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資料タイプ |
学術雑誌論文
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言語 |
英語
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OAI-PMH Set |
岡山大学
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著作権者 | © The Author(s) 2023.
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論文のバージョン | publisher
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PubMed ID | |
DOI | |
Web of Science KeyUT | |
関連URL | isVersionOf https://doi.org/10.1186/s13256-023-03776-6
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ライセンス | http://creativecommons.org/licenses/by/4.0/
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