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ID 58107
フルテキストURL
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著者
Yu, Yinghua Graduate School of Interdisciplinary Science and Engineering in Health Systems,Okayama University ORCID
Huber, Laurentius Section on Functional Imaging Methods, National Institute of Mental Health
Yang, Jiajia Graduate School of Interdisciplinary Science and Engineering in Health Systems,Okayama University
Jangraw, David C. Section on Functional Imaging Methods, National Institute of Mental Health
Handwerker, Daniel A. Section on Functional Imaging Methods, National Institute of Mental Health
Molfese, Peter J. Section on Functional Imaging Methods, National Institute of Mental Health
Chen, Gang Scientific and Statistical Computing Core, National Institute of Mental Health
Ejima, Yoshimichi Graduate School of Interdisciplinary Science and Engineering in Health Systems,Okayama University Kaken ID
Wu, Jinglong Graduate School of Interdisciplinary Science and Engineering in Health Systems,Okayama University
Bandettini, Peter A. Section on Functional Imaging Methods, National Institute of Mental Health
抄録
When humans perceive a sensation, their brains integrate inputs from sensory receptors and process them based on their expectations. The mechanisms of this predictive coding in the human somatosensory system are not fully understood. We fill a basic gap in our understanding of the predictive processing of somatosensation by examining the layer-specific activity in sensory input and predictive feedback in the human primary somatosensory cortex (S1). We acquired submillimeter functional magnetic resonance imaging data at 7T (n = 10) during a task of perceived, predictable, and unpredictable touching sequences. We demonstrate that the sensory input from thalamic projects preferentially activates the middle layer, while the superficial and deep layers in S1 are more engaged for cortico-cortical predictive feedback input. These findings are pivotal to understanding the mechanisms of tactile prediction processing in the human somatosensory cortex.
発行日
2019-05-01
出版物タイトル
Science Advances
5巻
5号
出版者
American Association for the Advancement of Science
開始ページ
eaav9053
ISSN
2375-2548
資料タイプ
学術雑誌論文
言語
English
OAI-PMH Set
岡山大学
著作権者
© 2019 The Authors
論文のバージョン
publisher
PubMed ID
DOI
Web of Science KeyUT
関連URL
isVersionOf https://doi.org/10.1126/sciadv.aav9053
ライセンス
http://creativecommons.org/licenses/by/4.0/
助成機関名
日本学術振興会
助成番号
JP17J40084
JP18K15339
JP18H05009
JP17K18855