ID | 57217 |
フルテキストURL | |
著者 |
Ueno, Hiroshi
Department of Medical Technology, Kawasaki University of Medical Welfare
Shimada, Atsumi
Division of Food and Nutrition, Nakamura Gakuen University Junior College
Suemitsu, Shunsuke
Department of Psychiatry, Kawasaki Medical School
Murakami, Shinji
Department of Psychiatry, Kawasaki Medical School
Kitamura, Naoya
Department of Psychiatry, Kawasaki Medical School
Wani, Kenta
Department of Psychiatry, Kawasaki Medical School
Matsumoto, Yosuke
Department of Neuropsychiatry, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
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Okamoto, Motoi
Department of Medical Technology, Graduate School of Health Sciences, Okayama University
Kaken ID
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Fujiwara, Yuko
Department of Health and Sports Science, Kawasaki University of Medical Welfare
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Ishihara, Takeshi
Department of Psychiatry, Kawasaki Medical School
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抄録 | Rosa gallica, a plant of the Rosa genus, has been used widely since the 13th century and is cultivated in many areas as a medicinal plant for the preparation of herbal medicines. However, details of the neuropsychological effects of R. gallica remain unclear; therefore we aimed to investigate the neuropsychological effects of a water-soluble extract of R. gallica in male C57BL/6N mice under normal conditions and under chronic stress. We administered a water-soluble extract of R. gallica to mice and performed a series of behavioral experiments to compare the treated animals with the untreated controls. No significant differences in activity level, anxiety-like behavior, depression-like behavior, body weight, and body temperature were observed between R. gallica-treated mice and control mice. However, in mice subjected to chronic stress, the observed decrease in activity was smaller in the R. gallica-treated mice than in the control mice. The oral administration of R. gallica did not affect the normal behavior of mice. However, when the mice were subjected to stress, R. gallica exerted an anti-stress effect. Therefore, R. gallica has potential as a medicinal plant for the purpose of stress prevention.
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キーワード | Neuroscience
Physiology
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発行日 | 2019-06
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出版物タイトル |
Heliyon
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巻 | 5巻
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号 | 6号
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出版者 | Elsevier
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開始ページ | e01945
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ISSN | 2405-8440
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資料タイプ |
学術雑誌論文
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言語 |
英語
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OAI-PMH Set |
岡山大学
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著作権者 | © 2019 The Authors.
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論文のバージョン | publisher
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PubMed ID | |
DOI | |
Web of Science KeyUT | |
関連URL | isVersionOf https://doi.org/10.1016/j.heliyon.2019.e01945
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ライセンス | http://creativecommons.org/licenses/by-nc-nd/4.0/
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