ID | 56681 |
フルテキストURL | |
著者 |
Elgaml, Abdelaziz
Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
Miyoshi, Shin-ichi
Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
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抄録 | Vibrio vulnificus is a halophilic estuarine bacterium, but this species causes fatal septicemia in humans. V. vulnificus may encounter many kinds of stresses either in the natural environment or in the human body. One of the striking stresses is the exposure to the reactive oxygen species including nitric oxide (NO). The present study revealed that NO could participate in the regulation of the V. vulnificus community behavior. When the bacterium was cultivated in the presence of sub-lethal doses of an NO donor, the expression of the genes encoding NO-detoxifying enzymes was significantly increased. The NO donor was also found to cause significant increase in production of a metalloprotease, a putative virulence factor, by the bacterium.
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キーワード | Vibrio vulnificus
Nitric oxide
Oxidative stress
Detoxification
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備考 | Note
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発行日 | 2015
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出版物タイトル |
Biocontrol Science
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巻 | 20巻
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号 | 3号
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出版者 | The Society for Antibacterial and Antifungal Agents
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開始ページ | 199
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終了ページ | 203
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ISSN | 13424815
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NCID | AA11169621
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資料タイプ |
学術雑誌論文
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言語 |
英語
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OAI-PMH Set |
岡山大学
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論文のバージョン | publisher
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PubMed ID | |
DOI | |
Web of Science KeyUT | |
関連URL | isVersionOf https://doi.org/10.4265/bio.20.199
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プロジェクト |
インド感染症共同研究
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