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ID 48272
フルテキストURL
著者
Ghosh, S Department of Hygiene, Sapporo Medical University School of Medicine, S 1,W 17, Chuo-Ku, Sapporo
Kobayashi, N Department of Hygiene, Sapporo Medical University School of Medicine, S 1,W 17, Chuo-Ku, Sapporo
Nagashima, S Division of Virology, Department of Infection and Immunity, Jichi Medical University School of Medicine
Chawla-Sarkar, M Division of Virology, National Institute of Cholera and Enteric Diseases
Krishnan, T Division of Virology, National Institute of Cholera and Enteric Diseases
Ganesh, B Division of Virology, National Institute of Cholera and Enteric Diseases
Naik, TN School of Biology, National Institute of Science Education and Research
抄録
Studies on bovine group B rotaviruses (GBRs) are limited. To date, only the VP6 gene of a single bovine GBR strain and the VP7 and NSP5 genes of a few bovine GBR strains have been sequenced and analyzed. In the present study, using a single-primer amplification method, we have determined the full-length nucleotide sequences of the VP1, VP2, VP4, VP6, NSP1 and NSP2 genes of three bovine GBR strains from eastern India. In all six of these genes, the bovine GBR strains shared high genetic relatedness among themselves but exhibited high genetic diversity with cognate genes of human, murine and ovine GBRs. Interestingly, as with group A rotaviruses, the bovine GBR VP1, VP2, VP6 and NSP2 genes appeared to be more conserved than the VP4 and NSP1 genes among strains of different species. The present study provides important insights into the genetic makeup and diversity of bovine GBRs, and also identifies a novel GBR VP4 genotype.
発行日
2009-11-21
出版物タイトル
Archives of Virology
155巻
2号
出版者
Springer
開始ページ
159
終了ページ
167
ISSN
0304-8608
NCID
AA00548901
資料タイプ
学術雑誌論文
プロジェクト
インド感染症共同研究
オフィシャル URL
http://www.springerlink.com/content/f24n7361k1370257/
言語
English
OAI-PMH Set
岡山大学
著作権者
© Springer-Verlag 2009
論文のバージョン
author
査読
有り
DOI
PubMed ID
Web of Sience KeyUT