ID | 54978 |
JaLCDOI | |
フルテキストURL | |
著者 |
Tanaka, Takashi
Department of Radiology, Okayama University Hospital
Soh, Junichi
Department General Thoracic Surgery, Okayama University Hospital
ORCID
Kaken ID
researchmap
Matsushita, Toshi
Department of Radiology, Okayama University Hospital
Toyooka, Shinichi
Department General Thoracic Surgery, Okayama University Hospital
ORCID
Kaken ID
publons
researchmap
Miyoshi, Shinichiro
Department General Thoracic Surgery, Okayama University Hospital
Kaken ID
publons
researchmap
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抄録 | We retrospectively assessed the dual-time-point (DTP) F-18 FDG PET/CT findings of thymic epithelial neoplasms (TENs) and investigated the diagnostic capacity of PET/CT compared to that of CT for predicting carcinoma. We calculated the ratio of the standardized uptake value of the tumor and that of the aortic arch (T/M ratio) for both the 90-min early scan and the 2-h delayed scan in 56 TEN patients. We used a multivariate logistic regression (MLR) analysis to estimate the CT features of carcinoma. We compared the diagnostic capacities of PET/CT and chest CT using receiver operating characteristic (ROC) analyses. The ROC curve revealed that the appropriate cut-off T/M ratio value for the highest accuracy was 2.39 with 75.0% accuracy. The area under the curve (AUC) was 0.855. The statistical analyses for DTP scans of 35 TEN patients demonstrated 74.3% accuracy and 0.838 AUC for the early scan versus 82.9% and 0.825 for the delayed scan. The MLR analysis indicated that mediastinal fat infiltration was a predictor of carcinoma. The ROC curve obtained for the model yielded an AUC of 0.853. Delayed scanning could improve the diagnostic capacity for carcinoma. The T/M ratio and mediastinal fat infiltration are predictive of carcinoma with moderate diagnostic accuracy.
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キーワード | thymic epithelial neoplasm
thymic carcinoma
thymoma
dual-time-point PET/CT
chest CT
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Amo Type | Original Article
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出版物タイトル |
Acta Medica Okayama
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発行日 | 2017-04
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巻 | 71巻
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号 | 2号
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出版者 | Okayama University Medical School
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開始ページ | 105
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終了ページ | 112
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ISSN | 0386-300X
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NCID | AA00508441
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資料タイプ |
学術雑誌論文
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言語 |
英語
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著作権者 | CopyrightⒸ 2017 by Okayama University Medical School
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論文のバージョン | publisher
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査読 |
有り
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PubMed ID |