このエントリーをはてなブックマークに追加
ID 31572
JaLCDOI
フルテキストURL
fulltext.pdf 1.28 MB
著者
Tanabe, Kozo Okayama University
Takahashi, Kiyoshi Okayama University
Maeda, Masanori Okayama Univeristy
Kimura, Ikuro Okayama University
抄録

To confirm the formation of Charcot-Leyden crystals (CLC) in basophils, we observed basophils in sputum and peripheral blood. Sealed slide and suspension culture methods were used to observe the process of CLC formation in peripheral blood basophils and eosinophils under electron microscopy. CLC formation was observed in basophils and eosinophils, and was found to be augmented by sealed slide method. A temperature of 4 degrees C was better than 37 degrees C for promoting the formation of crystals. There was no correlation between the degranulation of these cells and the formation of CLC after stimulation with anti-IgE or anti-IgG antibodies. CLC were initially detected in the cytoplasmic granules of basophils where they continued to enlarge. No CLC were identified in mast cells under any conditions studied. These findings confirm that CLC in sputum are not exclusive to eosinophils and that CLC appear to be present in basophil-rich sites under the cell damage.

キーワード
Charcot-Leyden crystals
basphils
electron microscopy
Amo Type
Article
出版物タイトル
Acta Medica Okayama
発行日
1993-04
47巻
2号
出版者
Okayama University Medical School
開始ページ
85
終了ページ
90
ISSN
0386-300X
NCID
AA00508441
資料タイプ
学術雑誌論文
言語
英語
論文のバージョン
publisher
査読
有り
PubMed ID
Web of Science KeyUT