ID | 48560 |
JaLCDOI | |
フルテキストURL | |
著者 |
Kataoka, Masaki
Departments of Orthopaedic Surgery, Okayama University Graduate School of Medicine
Kunisada, Toshiyuki
Medical Materials for Musculoskeletal Reconstruction, Okayama University Graduate School of Medicine
Kaken ID
researchmap
Tanaka, Masato
Departments of Orthopaedic Surgery, Okayama University Graduate School of Medicine
ORCID
Kaken ID
publons
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Takeda, Ken
Departments of Orthopaedic Surgery, Okayama University Graduate School of Medicine
Itani, Satoru
Departments of Orthopaedic Surgery, Okayama University Graduate School of Medicine
Sugimoto, Yoshihisa
Departments of Orthopaedic Surgery, Okayama University Graduate School of Medicine
Kaken ID
Misawa, Haruo
Departments of Orthopaedic Surgery, Okayama University Graduate School of Medicine
Nakahara, Shinnosuke
Department of Orthopaedic Surgery, Okayama Medical Center
Ozaki, Toshifumi
Departments of Orthopaedic Surgery, Okayama University Graduate School of Medicine
Kaken ID
publons
researchmap
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抄録 | There are a variety of treatment options for patients with spinal metastasis, and predicting prognosis is essential for selecting the proper treatment. The purpose of the present study was to identify the significant prognostic factors for the survival of patients with spinal metastasis. We retrospectively reviewed 143 patients with spinal metastasis. The median age was 61 years. Eleven factors reported previously were analyzed using the Cox proportional hazards model:gender, age, performance status, neurological deficits, pain, type of primary tumor, metastasis to major organs, previous chemotherapy,
disease-free interval before spinal metastasis, multiple spinal metastases, and extra-spinal bone metastasis. The average survival of study patients after the first visit to our clinic was 22 months. Multivariate survival analysis demonstrated that type of primary tumor (hazard ratio [HR]=6.80, p<0.001), metastasis to major organs (HR=2.01, p=0.005), disease-free interval before spinal metastasis
(HR=1.77, p=0.028), and extra-spinal bone metastasis (HR=1.75, p=0.017) were significant prognostic factors. Type of primary tumor was the most powerful prognostic factor. Other prognostic
factors may differ among the types of primary tumor and may also be closely associated with primary
disease activity. Further analysis of factors predicting prognosis should be conducted with respect to each type of primary tumor to help accurately predict prognosis.
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キーワード | spine
metastasis
survival
prognostic factor
cancer
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Amo Type | Original Article
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出版物タイトル |
Acta Medica Okayama
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発行日 | 2012-06
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巻 | 66巻
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号 | 3号
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出版者 | Okayama University Medical School
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開始ページ | 213
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終了ページ | 219
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ISSN | 0386-300X
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NCID | AA00508441
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資料タイプ |
学術雑誌論文
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言語 |
英語
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著作権者 | CopyrightⒸ 2012 by Okayama University Medical School
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論文のバージョン | publisher
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査読 |
有り
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PubMed ID | |
Web of Science KeyUT |