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ID 49924
フルテキストURL
著者
Shimoura, Yasumasa Kagawa Prefectural Cent Hosp, Clin Lab, Dept Pathol
Sato, Yasuharu Okayama Univ, Grad Sch Med Dent & Pharmaceut Sci, Dept Pathol ORCID Kaken ID researchmap
Takata, Katsuyoshi Okayama Univ, Grad Sch Med Dent & Pharmaceut Sci, Dept Pathol Kaken ID
Orita, Yorihisa Okayama Univ, Grad Sch Med Dent & Pharmaceut Sci, Dept Otolaryngol Head & Neck Surg
Nakamura, Satoko Kagawa Prefectural Cent Hosp, Clin Lab, Dept Pathol
Mano, Shyouhe Kagawa Prefectural Cent Hosp, Clin Lab, Dept Pathol
Yoshino, Tadashi Okayama Univ, Grad Sch Med Dent & Pharmaceut Sci, Dept Pathol
抄録
Objective: We examined the usefulness of light-chain restriction (LCR) on immunocytochemical double staining (IDS) for cytological diagnosis. Study Design: We investigated LCR on IDS in 40 patients with proliferative lymphatic disorders (23 with B cell lymphoma, 13 with reactive lymphoid lesions, 2 with T cell lymphoma and 2 with Hodgkin's lymphoma). In addition, the results of flow cytometry (FCM) were compared in 34 of these patients. Results: On IDS, LCR was detected in 21 of 23 patients (91.3%) with B cell lymphoma. On FCM, it was detected in 15 of 21 patients (71.4%) with B cell lymphoma. Neither IDS nor FCM showed LCR in any patients with reactive lesions, T cell lymphoma or Hodgkin's lymphoma. Conclusion: IDS facilitated the detection of LCR with a single specimen under morphological observation. The application of this procedure may improve the accuracy of cytological diagnosis.
キーワード
Cytology
Immunocytochemical
double staining
Immunoglobulin light-chain restriction
Lymph node
B cell lymphoma
Flow cytometry
発行日
2013
出版物タイトル
Acta Cytologica
57巻
1号
開始ページ
84
終了ページ
90
ISSN
0001-5547
資料タイプ
学術雑誌論文
オフィシャル URL
http://dx.doi.org/10.1159/000342475
関連URL
http://ousar.lib.okayama-u.ac.jp/metadata/49730
言語
English
著作権者
Copyright 2012 S. Karger AG, Basel
論文のバージョン
author
査読
有り
DOI
Web of Science KeyUT