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ID 49924
フルテキストURL
著者
Shimoura, Yasumasa Kagawa Prefectural Cent Hosp, Clin Lab, Dept Pathol
Sato, Yasuharu Okayama Univ, Grad Sch Med Dent & Pharmaceut Sci, Dept Pathol ORCID Kaken ID researchmap
Takata, Katsuyoshi Okayama Univ, Grad Sch Med Dent & Pharmaceut Sci, Dept Pathol Kaken ID publons
Orita, Yorihisa Okayama Univ, Grad Sch Med Dent & Pharmaceut Sci, Dept Otolaryngol Head & Neck Surg Kaken ID publons researchmap
Nakamura, Satoko Kagawa Prefectural Cent Hosp, Clin Lab, Dept Pathol
Mano, Shyouhe Kagawa Prefectural Cent Hosp, Clin Lab, Dept Pathol
Yoshino, Tadashi Okayama Univ, Grad Sch Med Dent & Pharmaceut Sci, Dept Pathol
抄録
Objective: We examined the usefulness of light-chain restriction (LCR) on immunocytochemical double staining (IDS) for cytological diagnosis. Study Design: We investigated LCR on IDS in 40 patients with proliferative lymphatic disorders (23 with B cell lymphoma, 13 with reactive lymphoid lesions, 2 with T cell lymphoma and 2 with Hodgkin's lymphoma). In addition, the results of flow cytometry (FCM) were compared in 34 of these patients. Results: On IDS, LCR was detected in 21 of 23 patients (91.3%) with B cell lymphoma. On FCM, it was detected in 15 of 21 patients (71.4%) with B cell lymphoma. Neither IDS nor FCM showed LCR in any patients with reactive lesions, T cell lymphoma or Hodgkin's lymphoma. Conclusion: IDS facilitated the detection of LCR with a single specimen under morphological observation. The application of this procedure may improve the accuracy of cytological diagnosis.
キーワード
Cytology
Immunocytochemical
double staining
Immunoglobulin light-chain restriction
Lymph node
B cell lymphoma
Flow cytometry
発行日
2013
出版物タイトル
Acta Cytologica
57巻
1号
開始ページ
84
終了ページ
90
ISSN
0001-5547
資料タイプ
学術雑誌論文
オフィシャル URL
http://dx.doi.org/10.1159/000342475
関連URL
http://ousar.lib.okayama-u.ac.jp/metadata/49730
言語
English
著作権者
Copyright 2012 S. Karger AG, Basel
論文のバージョン
author
査読
有り
DOI
Web of Science KeyUT