ID | 61417 |
フルテキストURL | |
著者 |
Sato, Keita
Department of Cytology and Histology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
ORCID
Kaken ID
publons
researchmap
Nwe, Khine Nwe
Department of Cytology and Histology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
Ohuchi, Hideyo
Department of Cytology and Histology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
ORCID
Kaken ID
researchmap
|
抄録 | The photoreceptor protein, opsin, is one of the major components for vision and photoreceptive function in animals. Although many opsins have been discovered from animal genomes, only a few nonimage‐forming functions mediated by opsins have been identified. Understanding the mRNA distribution of photoreceptor proteins is one crucial step in uncovering their photoreceptive function in animals. Here, we focus on the medaka fish (Oryzias latipes) Opsin 3 (Opn3)/Teleost multiple opsin (Tmt) system, which constitutes a separate phylogenetic group, having putative blue light photoreceptors for nonimage‐forming functions. In medaka, there is one opn3 and five tmt‐opsin orthologs. The expression pattern of the opn3/tmt‐opsins in the retina and brain was investigated by in situ hybridization. mRNAs for opn3/tmt‐opsins were distributed in the retinal ganglion cells as well as interneurons and specific brain nuclei. Specifically, hybridization signals were observed in the glutamate decarboxylase 1 (gad1)‐expressing amacrine cells for opn3, tmt1a, tmt1b, and tmt2, in the caudal lobe of the cerebellum for tmt1b and tmt2, in the cranial nerve nuclei for opn3, tmt1a, tmt1b, tmt2, and in the rostral pars distalis (adenohypophysis) for opn3. These expression patterns suggest that blue light sensing in the fish retina and brain may be involved in the integration of visual inputs, vestibular function, somatosensation, motor outputs, and pituitary endocrine regulation.
|
キーワード | medaka
nonimage‐forming photoreception
opn3
opsin
tmt‐opsin
RRID:SCR_018163
RRID:SCR_003070
RRID:SCR_005887
RRID:SCR_004860
RRID:SCR_010279
RRID:AB_2336524
RRID:AB_514497
RRID:AB_514504
RRID:AB_2339038
RRID: AB_840257
|
備考 | This is the peer reviewed version of the following article: [Sato, K, , KNN, Ohuchi, H. The Opsin 3/Teleost multiple tissue opsin system: mRNA localization in the retina and brain of medaka (Oryzias latipes). J Comp Neurol. 2021; 529: 2484– 2516. https://doi.org/10.1002/cne.25106], which has been published in final form at [https://doi.org/10.1002/cne.25106]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages there of by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.
|
発行日 | 2021-01-11
|
出版物タイトル |
Journal of Comparative Neurology
|
巻 | 529巻
|
出版者 | Wiley
|
開始ページ | 2484
|
終了ページ | 2516
|
ISSN | 0021-9967
|
NCID | AA00695917
|
資料タイプ |
学術雑誌論文
|
言語 |
英語
|
OAI-PMH Set |
岡山大学
|
著作権者 | © 2021 Wiley Periodicals LLC
|
論文のバージョン | author
|
PubMed ID | |
DOI | |
Web of Science KeyUT | |
関連URL | isVersionOf https://doi.org/10.1002/cne.25106
|
ライセンス | http://onlinelibrary.wiley.com/termsAndConditions#vor|http://doi.wiley.com/10.1002/tdm_license_1.1
|
Citation | Sato, K, , KNN, Ohuchi, H. The Opsin 3/Teleost multiple tissue opsin system: mRNA localization in the retina and brain of medaka (Oryzias latipes). J Comp Neurol. 2021; 529: 2484– 2516. https://doi.org/10.1002/cne.25106
|
助成機関名 |
Japan Society for the Promotion of Science
|
助成番号 | 17K15159
|