中村圭一郎

Multicenter, open-label, randomized, controlled study to test the utility of electronic patient-reported outcome monitoring in patients with unresectable advanced cancers or metastatic/recurrent solid tumors

フルテキストURL	fulltext.pdf
著者	Taira, Naruto\| Kiyota, Naomi\| Kikawa, Yuichiro\| Ichihara, Eiki\| Kato, Kyoko\| Kubota, Kaoru\| Tateishi, Ryosuke\| Nakata, Akinobu\| Nakamura, Keiichiro\| Narita, Yukiya\| Hotta, Katsuyuki\| Iwata, Hiroji\| Gemma, Akihiko\| Shimozuma, Kojiro\| Muro, Kei\| Iwamoto, Tetsuya\| Takumoto, Yuki\| Shiroiwa, Takeru\| Fukuda, Takashi\| Yamaguchi, Takuhiro\| Hagiwara, Yasuhiro\| Minami, Hironobu\|
キーワード	electronic patient-reported outcomes monitoring advanced cancers systemic chemotherapy randomized controlled study quality of life overall survival
発行日	2025-02-23
出版物タイトル	Japanese Journal of Clinical Oncology
巻	55巻
号	5号
出版者	Oxford University Press (OUP)
開始ページ	547
終了ページ	555
ISSN	1465-3621
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2025.
論文のバージョン	publisher
PubMed ID	39987488
DOI	10.1093/jjco/hyaf033
Web of Science KeyUT	001431225500001
関連URL	isVersionOf https://doi.org/10.1093/jjco/hyaf033

Factors associated with period of sick leave after gynecologic cancer treatment: a prospective cohort study

フルテキストURL	fulltext.pdf
著者	Tani, Yoshinori\| Nakamura, Keiichiro\| Sugihara, Hanako\| Shirakawa, Shinsuke\| Matsuoka, Hirofumi\| Ida, Naoyuki\| Haraga, Junko\| Ogawa, Chikako\| Eto, Eriko\| Nagao, Shoji\| Masuyama, Hisashi\|
キーワード	Period of sick leave Surgery plus chemotherapy Six or more cycles of chemotherapy Gynecologic cancer survivors
発行日	2025-11-19
出版物タイトル	Supportive Care in Cancer
巻	33巻
号	12号
出版者	Springer Science and Business Media LLC
開始ページ	1087
ISSN	0941-4355
NCID	AA10996793
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2025
論文のバージョン	publisher
PubMed ID	41258502
DOI	10.1007/s00520-025-10116-5
Web of Science KeyUT	001619218200007
関連URL	isVersionOf https://doi.org/10.1007/s00520-025-10116-5

The Concept of “Platinum Sensitivity” in Endometrial Cancer

フルテキストURL	fulltext.pdf
著者	Nagao, Shoji\| Fujikawa, Atsushi\| Imatani, Ryoko\| Tani, Yoshinori\| Matsuoka, Hirofumi\| Ida, Naoyuki\| Haraga, Junko\| Ogawa, Chikako\| Nakamura, Keiichiro\| Masuyama, Hisashi\|
キーワード	endometrial cancer platinum sensitivity platinum free interval
発行日	2025-08-02
出版物タイトル	Cancers
巻	17巻
号	15号
出版者	MDPI AG
開始ページ	2557
ISSN	2072-6694
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2025 by the authors.
論文のバージョン	publisher
PubMed ID	40805253
DOI	10.3390/cancers17152557
Web of Science KeyUT	001550660700001
関連URL	isVersionOf https://doi.org/10.3390/cancers17152557

Lymphadenectomy and chemotherapy are effective treatments for patients with 2023 international federation of gynecology and obstetrics stage IIC-high risk endometrial cancer in Japan

フルテキストURL	fulltext.pdf
著者	Tani, Yoshinori\| Nakamura, Keiichiro\| Yorimitsu, Masae\| Seki, Noriko\| Nakanishi, Mie\| Itou, Hironori\| Shimizu, Miyuki\| Yamamoto, Dan\| Takahara, Etsuko\| Masuyama, Hisashi\|
キーワード	Endometrial cancer FIGO 2023 Stage IIC high risk Lymphadenectomy Chemotherapy
備考	The version of record of this article, first published in International Journal of Clinical Oncology, is available online at Publisher’s website: http://dx.doi.org/10.1007/s10147-024-02647-4\|
発行日	2024-11-09
出版物タイトル	International Journal of Clinical Oncology
巻	30巻
号	1号
出版者	Springer Science and Business Media LLC
開始ページ	144
終了ページ	156
ISSN	1341-9625
NCID	AA11086579
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2024
論文のバージョン	publisher
PubMed ID	39516301
DOI	10.1007/s10147-024-02647-4
Web of Science KeyUT	001351172500001
関連URL	isVersionOf https://doi.org/10.1007/s10147-024-02647-4

ADAR1-high tumor-associated macrophages induce drug resistance and are therapeutic targets in colorectal cancer

フルテキストURL	fulltext.pdf
著者	Umeda, Hibiki\| Shigeyasu, Kunitoshi\| Takahashi, Toshiaki\| Moriwake, Kazuya\| Kondo, Yoshitaka\| Yoshida, Kazuhiro\| Takeda, Sho\| Yano, Shuya\| Matsumi, Yuki\| Kishimoto, Hiroyuki\| Fuji, Tomokazu\| Yasui, Kazuya\| Yamamoto, Hideki\| Takagi, Kosei\| Kayano, Masashi\| Michiue, Hiroyuki\| Nakamura, Keiichiro\| Mori, Yoshiko\| Teraishi, Fuminori\| Tazawa, Hiroshi\| Umeda, Yuzo\| Kagawa, Shunsuke\| Goel, Ajay\| Fujiwara, Toshiyoshi\|
キーワード	RNA-editing Macrophage Chemoresistance Biomarker Colorectal cancer
発行日	2025-04-16
出版物タイトル	Molecular Cancer
巻	24巻
号	1号
出版者	BMC
開始ページ	116
ISSN	1476-4598
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2025.
論文のバージョン	publisher
PubMed ID	40241135
DOI	10.1186/s12943-025-02312-y
Web of Science KeyUT	001470204500003
関連URL	isVersionOf https://doi.org/10.1186/s12943-025-02312-y

ADAR1 could be a potential diagnostic target for intrauterine infection patients

フルテキストURL	fulltext.pdf
著者	Nakamura, Keiichiro\| Shigeyasu, Kunitoshi\| Vu, Thuy Ha\| Maki, Jota\| Okamoto, Kazuhiro\| Masuyama, Hisashi\|
キーワード	ADAR1 Chorioamnionitis Funisitis Intrauterine infection Diagnostic biomarker
備考	The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-024-81097-4\|
発行日	2024-11-27
出版物タイトル	Scientific Reports
巻	14巻
号	1号
出版者	Nature Portfolio
開始ページ	29419
ISSN	2045-2322
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2024
論文のバージョン	publisher
PubMed ID	39592688
DOI	10.1038/s41598-024-81097-4
Web of Science KeyUT	001364770700004
関連URL	isVersionOf https://doi.org/10.1038/s41598-024-81097-4

Apolipoprotein-B mRNA-editing complex 3B could be a new potential therapeutic target in endometriosis

フルテキストURL	fulltext.pdf
著者	Vu, Thuy Ha\| Nakamura, Keiichiro\| Shigeyasu, Kunitoshi\| Kashino, Chiaki\| Okamoto, Kazuhiro\| Kubo, Kotaro\| Kamada, Yasuhiko\| Masuyama, Hisashi\|
キーワード	Apolipoprotein-B mRNA-editing complex 3B Endometriosis Apoptosis Potential therapeutic target
備考	The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-024-76589-2\|
発行日	2024-10-23
出版物タイトル	Scientific Reports
巻	14巻
号	1号
出版者	Nature Portfolio
開始ページ	24968
ISSN	2045-2322
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2024
論文のバージョン	publisher
PubMed ID	39443671
DOI	10.1038/s41598-024-76589-2
Web of Science KeyUT	001341352800136
関連URL	isVersionOf https://doi.org/10.1038/s41598-024-76589-2

Efficacy and safety of olaparib, olaparib plus bevacizumab and niraparib maintenance treatment in Japanese patients with platinum-sensitive advanced ovarian cancer

フルテキストURL	fulltext.pdf
著者	Nakamura, Keiichiro\| Matsuoka, Hirofumi\| Yorimitsu, Masae\| Ogawa, Mariko\| Kanemori, Miho\| Sueoka, Kotaro\| Kozai, Ayumi\| Nakamura, Hiroko\| Haruma, Tomoko\| Shiroyama, Yuko\| Hayata, Yuu\| Sugii, Hirokazu\| Ueda, Akiko\| Kurihara, Shuichi\| Urayama, Saiko\| Shimizu, Miyuki\| Masuyama, Hisashi\|
キーワード	olaparib olaparib plus bevacizumab niraparib renal function
発行日	2023-09-14
出版物タイトル	Japanese Journal of Clinical Oncology
巻	54巻
号	1号
出版者	Oxford University Press (OUP)
開始ページ	31
終了ページ	37
ISSN	1465-3621
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2023.
論文のバージョン	publisher
PubMed ID	37721176
DOI	10.1093/jjco/hyad125
Web of Science KeyUT	001068527100001
関連URL	isVersionOf https://doi.org/10.1093/jjco/hyad125

Not taking sick leave for gynecologic cancer treatment is negatively associated with returning to the same workplace

フルテキストURL	fulltext.pdf
著者	Nakamura, Keiichiro\| Matsuoka, Hirofumi\| Kubo, Kotaro\| Shirakawa, Shinsuke\| Ida, Naoyuki\| Haraga, Junko\| Ogawa, Chikako\| Okamoto, Kazuhiro\| Nagao, Shoji\| Masuyama, Hisashi\|
キーワード	returning to the same workplace gynecologic neoplasms sick leave
発行日	2023-11-23
出版物タイトル	Japanese Journal of Clinical Oncology
巻	54巻
号	3号
出版者	Oxford University Press (OUP)
開始ページ	292
終了ページ	296
ISSN	1465-3621
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2023.
論文のバージョン	publisher
PubMed ID	37995280
DOI	10.1093/jjco/hyad159
Web of Science KeyUT	001108594700001
関連URL	isVersionOf https://doi.org/10.1093/jjco/hyad159

ADAR1 has an oncogenic function and can be a prognostic factor in cervical cancer

フルテキストURL	fulltext.pdf
著者	Nakamura, Keiichiro\| Shigeyasu, Kunitoshi\| Okamoto, Kazuhiro\| Matsuoka, Hirofumi\| Masuyama, Hisashi\|
備考	The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-023-30452-y\|
発行日	2023-03-23
出版物タイトル	Scientific Reports
巻	13巻
号	1号
出版者	Nature Portfolio
開始ページ	4720
ISSN	2045-2322
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2023
論文のバージョン	publisher
PubMed ID	36959226
DOI	10.1038/s41598-023-30452-y
Web of Science KeyUT	001024033600064
関連URL	isVersionOf https://doi.org/10.1038/s41598-023-30452-y

ADAR1 is a promising risk stratification biomarker of remnant liver recurrence after hepatic metastasectomy for colorectal cancer

フルテキストURL	fulltext.pdf
著者	Hata, Nanako\| Shigeyasu, Kunitoshi\| Umeda, Yuzo\| Yano, Shuya\| Takeda, Sho\| Yoshida, Kazuhiro\| Fuji, Tomokazu\| Yoshida, Ryuichi\| Yasui, Kazuya\| Umeda, Hibiki\| Takahashi, Toshiaki\| Kondo, Yoshitaka\| Kishimoto, Hiroyuki\| Mori, Yoshiko\| Teraishi, Fuminori\| Yamamoto, Hideki\| Michiue, Hiroyuki\| Nakamura, Keiichiro\| Tazawa, Hiroshi\| Fujiwara, Toshiyoshi\|
備考	The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-023-29397-z\|
発行日	2023-02-06
出版物タイトル	Scientific Reports
巻	13巻
号	1号
出版者	Nature Portfolio
開始ページ	2078
ISSN	2045-2322
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2023
論文のバージョン	publisher
PubMed ID	36747029
DOI	10.1038/s41598-023-29397-z
Web of Science KeyUT	000989985700018
関連URL	isVersionOf https://doi.org/10.1038/s41598-023-29397-z

Tumor size before image-guided brachytherapy is an important factor of local control after radiotherapy for cervical squamous cell carcinoma: analysis in cases using central shielding

フルテキストURL	fulltext.pdf
著者	Yoshio, Kotaro\| Ihara, Hiroki\| Okamoto, Kazuhiro\| Suzuki, Etsuji\| Ogata, Takeshi\| Sugiyama, Soichi\| Nakamura, Keiichiro\| Nagao, Shoji\| Masuyama, Hisashi\| Hiraki, Takao\|
キーワード	cervical cancer tumor size squamous cell carcinoma image-guided brachytherapy (IGBT) central shielding (CS)
発行日	2022-07-05
出版物タイトル	Journal Of Radiation Research
出版者	Oxford University Press on behalf of The Japanese Radiation Research Society and Japanese Society for Radiation Oncology
ISSN	0449-3060
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2022.
論文のバージョン	publisher
PubMed ID	35791439
DOI	10.1093/jrr/rrac040
Web of Science KeyUT	000820941900001
関連URL	isVersionOf https://doi.org/10.1093/jrr/rrac040

The Combination of D-dimer and Glasgow Prognostic Score Can Be Useful in Predicting VTE in Patients with Stage IIIC and IVA Ovarian Cancer

JaLCDOI	10.18926/AMO/63406
フルテキストURL	76_2_129.pdf
著者	Kubo, Kotaro\| Nakamura, Keiichiro\| Okamoto, Kazuhiro\| Matsuoka, Hirofumi\| Ida, Naoyuki\| Haruma, Tomoko\| Ogawa, Chikako\| Masuyama, Hisashi\|
抄録	Cancer patients have increased risk of venous thromboembolism (VTE) that must be assessed before treatment. This study aimed to determine effective VTE biomarkers in gynecologic cancer (GC). We investigated the correlation between D-dimer levels, Khorana risk score (KRS), Glasgow prognostic score (GPS), and VTE in 1499 GC patients (583 cervical cancer (CC), 621 endometrial cancer (EC), and 295 ovarian cancer (OC) patients) treated at our institution between January 2008 and December 2019. χ2 and Mann–Whitney U-tests were used to determine statistical significance. We used receiver operating characteristic-curve analysis to evaluate the discriminatory ability of each parameter. D-dimer levels were significantly correlated with KRS and GPS in patients with GC. VTE was diagnosed in 11 CC (1.9%), 27 EC (4.3%), and 39 OC patients (13.2%). Optimal D-dimer cut-off values for VTE were 3.1, 3.2, and 3.9 μg/ml in CC, EC and OC patients, respectively. D-dimer could significantly predict VTE in all GC patients. Furthermore, D-dimer combined with GPS was more accurate in predicting VTE than other VTE biomarkers in stage IIIC and IVA OC (AUC: 0.846; p<0.001). This study demonstrates that combined D-dimer and GPS are useful in predicting VTE in patients with OC.
キーワード	D-dimer gynecologic cancer venous thromboembolism
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2022-04
巻	76巻
号	2号
出版者	Okayama University Medical School
開始ページ	129
終了ページ	135
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2022 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	35503440
Web of Science KeyUT	000792374900004

EG-VEGF Induces Invasion of a Human Trophoblast Cell Line via PROKR2

JaLCDOI	10.18926/AMO/62806
フルテキストURL	75_6_677.pdf
著者	Tani Kazumasa\| Mitsui, Takashi\| Mishima, Sakurako\| Ohira, Akiko\| Maki, Jota\| Eto, Eriko\| Hayata, Kei\| Nakamura, Keiichiro\| Masuyama, Hisashi\|
抄録	Extravillous trophoblast (EVT) invasion is important for embryo implantation, placental development, and successful remodeling of the uterine spiral artery. Endocrine gland derived-vascular endothelial growth factor (EG-VEGF) and matrix metalloproteinases (MMPs) are implicated in EVT invasion; however, the high con-centrations found in pregnancy pathologies have not been investigated in non-tumor trophoblasts. The roles of EG-VEGF, prokineticin receptors (PROKR1/2), MMP-2, and MMP-9 in EVT invasion during spiral artery remodeling were evaluated using human EVT from HTR-8/SVneo cell lines. The expression of MMP-2, MMP-9, and mitogen-activated protein kinase (MAPK), and Akt pathways in HTR-8/SVneo cells treated with recom-binant EG-VEGF alongside anti-PROKR1 and/or anti-PROKR2 antibodies was evaluated using quantitative reverse transcription-PCR and western blotting. Wound-healing and cell invasion assays were performed to assess the migration and invasion of these treated cells. Interestingly, 20 nM EG-VEGF activated ERK1/2 sig-naling and upregulated MMP-2 and MMP-9. This effect was suppressed by anti-PROKR2 antibody via ERK1/2 downregulation. Anti-PROKR2 antibody inhibited the migration and invasion of EG-VEGF-stimulated HTR-8/SVneo cells. Elevated concentrations of EG-VEGF enhance EVT invasion in a human trophoblast cell line by upregulating MMP-2 and MMP-9 via PROKR2. These new insights into the regulation of epithelial cell invasion may help in developing therapeutic interventions for placental-related diseases during pregnancy.
キーワード	endocrine gland-derived vascular endothelial growth factor prokineticin extravillous trophoblast matrix metalloproteinase obstetric diseases
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2021-12
巻	75巻
号	6号
出版者	Okayama University Medical School
開始ページ	677
終了ページ	684
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	34955534
Web of Science KeyUT	000735297900002
NAID	120007180286

Successful Treatment of Acute Promyelocytic Leukemia Complicated with Endometrial Cancer by Arsenic Trioxide

JaLCDOI	10.18926/AMO/61904
フルテキストURL	75_2_219.pdf
著者	Sugiura, Hiroyuki\| Nishimori, Hisakazu\| Matsuoka, Hirofumi\| Nakamura, Keiichiro\| Fujii, Keiko\| Fujii, Nobuharu \| Matsuoka, Ken-ichi \| Maeda, Yoshinobu\|
抄録	Acute promyelocytic leukemia (APL) is a hematological emergency that requires urgent intervention because of the high incidence of early hemorrhagic death. When patients with APL experience a synchronous solid organ tumor, the tumor’s treatment must also be done properly. Differentiation-inducing therapy using arsenic trioxide (ATO) has less hematological toxicity compared to cytotoxic chemotherapy and might be preferable for untreated APL patients with a synchronous solid organ tumor. Here we describe the first successful case of untreated APL and synchronous endometrial cancer (in an adult Japanese woman) treated with ATO consolidation therapy and the subsequent surgery and chemotherapy for endometrial cancer.
キーワード	acute promyelocytic leukemia endometrial cancer arsenic trioxide synchronous multiple primary malignant tumor chemotherapy
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2021-04
巻	75巻
号	2号
出版者	Okayama University Medical School
開始ページ	219
終了ページ	224
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	33953429
NAID	120007029883

The presence of chronic diseases contributes to the occurrence risk factors for gynecological cancers in Japan

フルテキストURL	fulltext.pdf
著者	Okamoto, Kazuhiro\| Nakamura, Keiichiro\| Matsuoka, Hirofumi\| Matsubara, Yuko\| Haraga, Junko\| Ogawa, Chikako\| Masuyama, Hisashi\|
キーワード	gynecological cancer chronic diseases occurrence risk factors
発行日	2020-01-29
出版物タイトル	Molecular and Clinical Oncology
巻	12巻
号	4号
出版者	Spandidos Publications
開始ページ	336
終了ページ	342
ISSN	2049-9450
NCID	AA12610944
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© Okamoto et al.
論文のバージョン	publisher
PubMed ID	32190316
DOI	10.3892/mco.2020.1989
Web of Science KeyUT	000523727300007
関連URL	isVersionOf https://doi.org/10.3892/mco.2020.1989

Risk of Gynecologic Cancer as Second versus First Primary Cancer in Japan

JaLCDOI	10.18926/AMO/58268
フルテキストURL	74_2_109.pdf
著者	Ogawa, Chikako\| Nakamura, Keiichiro\| Matsuoka, Hirofumi\| Matsubara, Yuko\| Haraga, Junko\| Masuyama, Hisashi\|
抄録	This study aimed to determine whether the risk conferred by gynecologic cancer (GC) as second primary cancer (SPC) differs from that associated with GC as first primary cancer (FPC). We investigated the correlations between FPC/SPC and the characteristics and prognoses of 1,645 GC patients (701 with cervical cancer [CC], 641 with endometrial cancer [EM], and 303 with ovarian cancer [OV]). The χ2 test and the Kaplan–Meier method were used to determine whether FPC/SPC and the characteristics and prognoses of GC patients. Of the SPC patients, 26 (3.7%) had CC, 53 (8.3%) had EM, and 31 (10.2%) had OV. The most common previous cancer type in SPC of GC patients was breast cancer, which was observed in 13 patients (50.0%) with CC, 23 (43.4%) with EM, and 16 (51.6%) with OV. In all patients with CC, EM, and OV as SPC, the stage was significantly associated with recurrence. There were no significant differences in the morbidity or mortality of CC, EM, or OV patients between those with FPC and those with SPC. The risk of SPC development in GC patients varied, ranging from 3.5% (CC) to 10.3% (OV) of patients.
キーワード	second primary cancer gynecologic cancer prognosis
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2020-04
巻	74巻
号	2号
出版者	Okayama University Medical School
開始ページ	109
終了ページ	114
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2020 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	32341584
Web of Science KeyUT	000528278500003
NAID	120006839447

Pure Choriocarcinoma of the Ovary in Silver-Russell Syndrome

JaLCDOI	10.18926/AMO/53526
フルテキストURL	69_3_183.pdf
著者	Haruma, Tomoko\| Ogawa, Chikako\| Nishida, Takeshi\| Kusumoto, Tomoyuki\| Nakamura, Keiichiro\| Seki, Noriko\| Katayama, Takaaki\| Hiramatsu, Yuji\|
抄録	Pure ovarian choriocarcinoma is an extremely rare malignancy that can be gestational or non-gestational in origin. Silver-Russell syndrome (SRS) is a rare congenital developmental disorder characterized by pre- and postnatal growth failure, relative macrocephaly, a triangular face, hemihypotrophy, and fifth-finger clinodactyly. We report a rare case of pure ovarian choriocarcinoma occurring in a 19-year-old woman with SRS. Following surgery, multiple chemotherapy courses were effective and she was free of disease at the 10-month follow-up.
キーワード	choriocarcinoma ovary Silver-Russell syndrome
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2015-06
巻	69巻
号	3号
出版者	Okayama University Medical School
開始ページ	183
終了ページ	188
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2015 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	26101195
Web of Science KeyUT	000356903000008

PET/CT SUVmaxは子宮体癌の予後不良因子になりうる

タイトル（別表記）	A preoperative SUVmax greater than the ADCmin of the primary tumour : A predictor of disease recurrence and survival in patients with endometrial cancer
フルテキストURL	126_11.pdf
著者	中村圭一郎\| 上者郁夫\| 福島千加子\| 春間朋子\| 林千晶\| 楠本知行\| 関典子\| 本郷淳司\| 平松祐司\|
キーワード	endometrial cancer SUVmax PET/CT predictor of poor prognosis
出版物タイトル	岡山医学会雑誌
発行日	2014-04-01
巻	126巻
号	1号
開始ページ	11
終了ページ	15
ISSN	0030-1558
関連URL	http://www.okayama-u.ac.jp/user/oma/
言語	日本語
著作権者	Copyright (c) 2014 岡山医学会
論文のバージョン	publisher
DOI	10.4044/joma.126.11

Three Cases of Struma Ovarii Underwent Laparoscopic Surgery with Definite Preoperative Diagnosis

JaLCDOI	10.18926/AMO/50413
フルテキストURL	67_3_191.pdf
著者	Binti Md Nor, Nurliza\| Kusumoto, Tomoyuki\| Inoue, Seiji\| Nakamura, Keiichiro\| Seki, Noriko\| Hongo, Atsushi\| Kodama, Junichi\| Hiramatsu, Yuji\|
抄録	Struma ovarii is a rare neoplasm that accounts for approximately 0.3ｵ of ovarian tumors. Due to its ultrasound morphology, which is quite similar to that of malignant ovarian carcinoma, most struma ovarii cases are open operated with laparotomy rather than laparoscopy. We present 3 cases of struma ovarii, which were diagnosed preoperatively by imaging studies and removed by laparoscopic surgery. All patients were premenopausal women between ages 31‒50. The magnetic resonance imaging (MRI) findings were complex masses composed of multiple cysts and solid components with T2-hypointense regions as well as multiple T1-hyperintense cystic areas, findings that are typical for struma ovarii. A combination of plain computed tomography (CT), positron emission tomography (PET)-CT, and scintigraphy was useful for diagnosis. Laboratory examination revealed elevated serum thyroglobulin, which led to the diagnosis of struma ovarii. Laparoscopic surgeries were performed without rupturing the tumors. Although it has been difficult to differentiate between struma ovarii and malignant tumors by conventional methods, recently MRI techniques appear make it possible to diagnose struma ovarii preoperatively from the abovementioned imaging characteristic, together with laboratory data. As for treatment, we think laparoscopy could be successful for struma ovarii, but the surgeon must be careful not to rupture the tumor intra-abdominally in order to prevent dissemination, which could lead to malignancy.
キーワード	struma ovarii ovarian neoplasms MRI laparoscopic surgery
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2013-06
巻	67巻
号	3号
出版者	Okayama University Medical School
開始ページ	191
終了ページ	195
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2013 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	23804143
Web of Science KeyUT	000320747900009

中村 圭一郎