ID | 62300 |
フルテキストURL | |
著者 |
Nishii, Nobuhiro
Department of Cardiovascular Therapeutics, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences
Kaken ID
publons
Noda, Takashi
Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center
Nitta, Takashi
Department of Cardiovascular Surgery, Nippon Medical School
Aizawa, Yoshifusa
Department of Research and Development, Tachikawa Medical Center
Ohe, Tohru
Okayama City Hospital
Kurita, Takashi
Department of Internal Medicine, Faculty of Medicine, Kindai University
|
抄録 | Introduction: Various risk factors for the first inappropriate implantable cardioverter-defibrillator (ICD) therapy event have been reported, including a history of atrial fibrillation/atrial flutter (AF/AFL), younger age, and multiple zones. Nonetheless, which factors are concordant with real-world data has not been clarified, and risk factors for the second inappropriate ICD therapy event have not been well examined. This study aimed to clarify the risk factors for the first and second inappropriate ICD therapy events.
Methods: We conducted a post-hoc secondary analysis of data from a multicenter, prospective observational study (the Nippon Storm Study) designed to clarify the risk factors for electrical storm. Results: The analysis included data from 1549 patients who received ICD or cardiac resynchronization therapy with defibrillator (CRT-D). Over a median follow-up of 28 months, 293 inappropriate ICD therapy events occurred in 153 (10.0%) patients. On multivariate Cox regression analysis, the risk factors for the first inappropriate ICD therapy event were younger age (hazard ratio [HR], 0.986; p = 0.028), AF/AFL (HR, 2.324; p = 0.002), ICD without CRT implantation (HR, 2.377; p = 0.004), and multiple zones (HR, 1.852; p = 0.010). "No-intervention" after the first inappropriate ICD therapy event was the sole risk factor for the second inappropriate ICD therapy event. Conclusions: Risk factors for the first inappropriate ICD therapy event were similar to those previously reported. Immediate intervention after the first inappropriate ICD therapy event could reduce the risk of the second inappropriate event. |
キーワード | Nippon storm study
Implantable cardioverter-defibrillator
Cardiac resynchronization therapy with defibrillator
Inappropriate ICD therapy
|
発行日 | 2021-06
|
出版物タイトル |
IJC Heart & Vasculature
|
巻 | 34巻
|
出版者 | Elsevier Ireland Ltd
|
開始ページ | 100779
|
ISSN | 2352-9067
|
資料タイプ |
学術雑誌論文
|
言語 |
英語
|
OAI-PMH Set |
岡山大学
|
著作権者 | © 2021 The Authors.
|
論文のバージョン | publisher
|
PubMed ID | |
DOI | |
Web of Science KeyUT | |
関連URL | isVersionOf https://doi.org/10.1016/j.ijcha.2021.100779
|
ライセンス | http://creativecommons.org/licenses/by-nc-nd/4.0/
|