ID | 61869 |
フルテキストURL | |
著者 |
Kawashima, Akira
Department of Radiology, Mayo Clinic
Marukawa, Yohei
Department of Radiology, Okayama University Hospital
Kitayama, Takahiro
Department of Radiology, Okayama University Hospital
Masaoka, Yoshihisa
Department of Radiology, Okayama University Hospital
Kojima, Katsuhide
Department of Radiology, Okayama University Hospital
Iguchi, Toshihiro
Department of Radiology, Okayama University Hospital
Kaken ID
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抄録 | More than 10 hereditary renal tumor syndromes (HRTSs) and related germline mutations have been reported with HRTS-associated renal and extrarenal manifestations with benign and malignant tumors. Radiologists play an important role in detecting solitary or multiple renal masses with or without extrarenal findings on imaging and may raise the possibility of an inherited predisposition to renal cell carcinoma, providing direction for further screening, intervention and surveillance of the patients and their close family members before the development of potentially lethal renal and extrarenal tumors. Renal cell carcinomas (RCCs) associated with von Hippel–Lindau disease are typically slow growing while RCCs associated with HRTSs, such as hereditary leiomyomatosis and renal cell carcinoma syndrome, are highly aggressive. Therefore, radiologists need to be familiar with clinical and imaging findings of renal and extrarenal manifestations of HRTSs. This article reviews clinical and imaging findings for the evaluation of patients with well-established HRTSs from a radiologist’s perspective to facilitate the clinical decision-making process for patient management.
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キーワード | Hereditary renal tumor syndrome
Von Hippel–Lindau disease
Birt–Hogg–Dubé syndrome
Tuberous sclerosis complex
Hereditary leiomyomatosis and renal cell carcinoma syndrome
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備考 | This is an Accepted Manuscript of an article published by Springer. This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/10.1007/s11604-021-01109-5
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発行日 | 2021-3-23
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出版物タイトル |
Japanese Journal of Radiology
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巻 | 39巻
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出版者 | Springer Science and Business Media LLC
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開始ページ | 619
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終了ページ | 632
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ISSN | 1867-1071
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NCID | AA12375935
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資料タイプ |
学術雑誌論文
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言語 |
英語
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OAI-PMH Set |
岡山大学
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著作権者 | ©Japan Radiological Society 2021
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論文のバージョン | author
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PubMed ID | |
NAID | |
DOI | |
Web of Science KeyUT | |
関連URL | isVersionOf https://doi.org/10.1007/s11604-021-01109-5
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ライセンス | http://www.springer.com/tdm|http://www.springer.com/tdm
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Citation | Tanaka T, Kawashima A, Marukawa Y, Kitayama T, Masaoka Y, Kojima K, Iguchi T, Hiraki T, Kanazawa S. Imaging evaluation of hereditary renal tumors: a pictorial review. Jpn J Radiol. 2021 Mar 23. doi: 10.1007/s11604-021-01109-5. Epub ahead of print. PMID: 33759057.
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