| JaLCDOI | 10.18926/AMO/54808 |
|---|---|
| フルテキストURL | 70_6_455.pdf |
| 著者 | Tanino, Masaaki| Kobayashi, Motomu| Sasaki, Toshihiro| Takata, Ken| Takeda, Yoshimasa| Mizobuchi, Satoshi| Morita, Kiyoshi| Nagai, Taku| Morimatsu, Hiroshi| |
| 抄録 | Postoperative cognitive dysfunction (POCD) occurs in nearly one-third of patients after non-cardiac surgery. Many animal behavior studies have investigated the effect of general anesthesia on cognitive function. However, there have been no studies examining the effects on working memory specifically, with a focus on the retention of working memory. We demonstrate here that isoflurane anesthesia induces deficits in the retention of spatial working memory in rats, as revealed by an increase in isoflurane-induced across-phase errors in the delayed spatial win-shift (SWSh) task with a 30-min delay in an 8-arm radial arm maze on post-anesthesia days (PADs) 1,2,4, and 10. A post-hoc analysis revealed a significant increase in across-phase errors on PAD 1 and recovery on PAD 10 in the isoflurane group. In contrast, within-phase errors independent of the retention of working memory were unaffected by isoflurane. These results demonstrate that isoflurane anesthesia transiently impairs the retention of spatial working memory in rats. |
| キーワード | postoperative cognitive dysfunction isoflurane spatial working memory retention delayed spatial win-shift task |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2016-12 |
| 巻 | 70巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 455 |
| 終了ページ | 460 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2016 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 28003670 |
| JaLCDOI | 10.18926/AMO/53027 |
|---|---|
| フルテキストURL | 68_6_375.pdf |
| 著者 | Yamanaka, Reiko| Soga, Yoshihiko| Moriya, Yoshie| Okui, Akemi| Takeuchi, Tetsuo| Sato, Kenji| Morimatsu, Hiroshi| Morita, Manabu| |
| 抄録 | We encountered a 74-year-old male patient with tongue laceration after convulsive seizures under intensive care. The tongue showed severe swelling, and the right ventral surface had been lacerated by his isolated and pointed right lower canine. Our university hospital has established a perioperative management center, and is promoting interprofessional collaboration, including dentists, in perioperative management. Dentists collaborating in the perioperative management center took dental impressions, with the support of anesthesiologists who opened the patientʼs jaw under propofol sedation, to produce a mouth protector. By raising the patientʼs bite, the completed mouth protector prevented the isolated tooth from contacting the tongue and protected the lacerated wound. Use of the mouth protector prevented the lacerated tongue from coming into contact with the pointed tooth, and the tongue healed gradually. These findings underscore that interprofessional collaboration including dentists can improve the quality of medical care. |
| キーワード | mouth protector tongue laceration |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2014-12 |
| 巻 | 68巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 375 |
| 終了ページ | 378 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2014 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 25519032 |
| Web of Science KeyUT | 000346882200008 |
| JaLCDOI | 10.18926/AMO/53023 |
|---|---|
| フルテキストURL | 68_6_339.pdf |
| 著者 | Nishie, Hiroyuki| Mizobuchi, Satoshi| Suzuki, Etsuji| Sato, Kenji| Toda, Yuichiro| Matsuoka, Junji| Morimatsu, Hiroshi| |
| 抄録 | The main purpose of this study was to determine the relationships between Japanese individualsʼ interest in living wills and their preferred end-of-life care and death locations. Questionnaires were mailed to 1,000 individuals aged ｧ50 to measure these 2 factors. We examined the associations between the respondentsʼ characteristics and their preferred care and death locations by using multinomial logistic regression models. The response rate was 74%. Home was the most frequently preferred place for end-of-life care (64%), and a palliative care unit (PCU) was the most commonly preferred place to die (51%). Living will interest was associated with a preference for care (odds ratio [OR] 4.74, 95% confidence interval [CI] 1.95-12.1) and death (OR 2.75, 95% CI 1.70-4.47) in a PCU rather than a hospital, but it was not associated with the choice between receiving care or dying at home instead of a hospital. We must consider why Japanese people think home death is impracticable. The Japanese palliative care system should be expanded to meet patientsʼ end-of-life needs, and this includes not only facilitating home care but also increasing access to PCU care. |
| キーワード | advance healthcare directive living will end-of-life care palliative care unit place of death |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2014-12 |
| 巻 | 68巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 339 |
| 終了ページ | 348 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2014 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 25519028 |
| Web of Science KeyUT | 000346882200004 |
| 関連URL | http://ousar.lib.okayama-u.ac.jp/metadata/53134 |
| 著者 | Tomotsuka, Naoto| Kaku, Ryuji| Obata, Norihiko| Matsuoka, Yoshikazu| Kanzaki, Hirotaka| Taniguchi, Arata| Muto, Noriko| Omiya, Hiroki| Itano, Yoshitaro| Sato, Tadasu| Ichikawa, Hiroyuki| Mizobuchi, Satoshi| Morimatsu, Hiroshi| |
|---|---|
| 発行日 | 2014-07-11 |
| 出版物タイトル | Journal of Pain Research |
| 巻 | 7巻 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | Tani, Makiko| Morimatsu, Hiroshi| Takatsu, Fumiaki| Morita, Kiyoshi| |
|---|---|
| 発行日 | 2012 |
| 出版物タイトル | The Scientific World Journal |
| 巻 | 2012巻 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | Kosaka, Junko| Morimatsu, Hiroshi| Takahashi, Toru| Shimizu, Hiroko| Kawanishi, Susumu| Omori, Emiko| Endo, Yasumasa| Tamaki, Naofumi| Morita, Manabu| Morita, Kiyoshi| |
|---|---|
| 発行日 | 2013-05-07 |
| 出版物タイトル | PLoS ONE |
| 巻 | 8巻 |
| 号 | 5号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | Matsumi, Junya| Morimatsu, Hiroshi| Matsusaki, Takashi| Kaku, Ryuji| Shimizu, Hiroko| Takahashi, Toru| Yagi, Takahito| Matsumi, Masaki| Morita, Kiyoshi| |
|---|---|
| 発行日 | 2012-02 |
| 出版物タイトル | International Journal of Molecular Medicine |
| 巻 | 29巻 |
| 号 | 2号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 森松 博史| |
|---|---|
| 発行日 | 2007-03-23 |
| 出版物タイトル | |
| 資料タイプ | 学位論文 |