ID | 57676 |
フルテキストURL | |
著者 |
Hiroi, Kazumasa
Department of Anesthesiology and Resuscitology, Okayama University Hospital
Matsusaki, Takashi
Department of Anesthesiology and Resuscitology, Okayama University Hospital
Kaken ID
Kaku, Ryuji
Department of Anesthesiology and Resuscitology, Okayama University Hospital
Kaken ID
publons
Umeda, Yuzo
Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Kaken ID
researchmap
Yagi, Takahito
Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Kaken ID
publons
researchmap
Morimatsu, Hiroshi
Department of Anesthesiology and Resuscitology, Okayama University Hospital
ORCID
Kaken ID
publons
researchmap
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抄録 | Background and aims: Postoperative hypoalbuminemia, especially following liver transplantation, can lead to adverse multisystem effects and even death. We investigated the relationship between postoperative albumin levels and organ failure (assessed using Sequential Organ Failure Assessment [SOFA] scores).
Methods: Sixty liver transplant recipients admitted to the intensive care unit (ICU) from 2012 to 2015 were retrospectively divided into 2 groups: lower albumin (LA) (n=28) and higher albumin (HA) (n=32), using whether serum albumin level fell below 3.0 g/dL during the first postoperative week as the stratifying factor. The SOFA scores (primary endpoint) and associated complications (ascites amount, rejection, re-intubation, abdominal re-operation, thrombosis), additional treatment (dialysis, pleural effusion drainage), and duration of ICU stay (secondary endpoints) of the 2 groups were compared. Results: Average serum albumin levels were significantly different between HA and LA groups (3.6 [3.4-3.8] vs 3.1 [2.9-3.3], respectively, P<.05), although the amounts of albumin infused in the 2 groups during the first postoperative week were not different (HA vs LA: 42 [30-71] vs 40 [30-58], respectively, P=.37). Mean daily SOFA scores were not significantly different between the HA and LA groups (8.3 [6.6-9.0] vs 7.2 [6.3-8.6], P=.73), although the HA group had lower mean cardiovascular SOFA sub-scores than the LA group (0.1 [0-0.4] vs 0.4 [0-1.3], P=.032). There were no significant differences between the groups with regard to complication rates and duration of ICU and hospital stays. Conclusions: Serum albumin level might not influence cumulative organ function, but it decreases the amount of hemodynamic support required in liver transplant recipients. |
発行日 | 2019-10-31
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出版物タイトル |
Transplantation Proceedings
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巻 | 51巻
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号 | 8号
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出版者 | Elsevier
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開始ページ | 2750
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終了ページ | 2754
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ISSN | 00411345
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資料タイプ |
学術雑誌論文
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言語 |
英語
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OAI-PMH Set |
岡山大学
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著作権者 | © 2019 The Authors. Published by Elsevier Inc.
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論文のバージョン | publisher
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PubMed ID | |
DOI | |
Web of Science KeyUT | |
関連URL | isVersionOf https://doi.org/10.1016/j.transproceed.2019.01.199
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ライセンス | http://creativecommons.org/licenses/by-nc-nd/4.0/
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Citation | Hiroi K, Matsusaki T, Kaku R, Umeda Y, Yagi T, Morimatsu H. Postoperative Course of Serum Albumin Levels and Organ Dysfunction After Liver Transplantation. Transplant Proc. 2019;51(8):2750‐2754. doi:10.1016/j.transproceed.2019.01.199
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オープンアクセス(出版社) |
OA
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オープンアーカイブ(出版社) |
非OpenArchive
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