フルテキストURL NatCommun_12138.pdf
著者 Huang, Xin-Yuan| Deng, Fenglin| Yamaji, Naoki| Pinson, Shannon R.M.| Fujii-Kashino, Miho| Danku, John| Douglas, Alex| Guerinot, Mary Lou| Salt, David E.| Ma, Jian Feng|
抄録 Rice is a major source of calories and mineral nutrients for over half the world's human population. However, little is known in rice about the genetic basis of variation in accumulation of copper (Cu), an essential but potentially toxic nutrient. Here we identify OsHMA4 as the likely causal gene of a quantitative trait locus controlling Cu accumulation in rice grain. We provide evidence that OsHMA4 functions to sequester Cu into root vacuoles, limiting Cu accumulation in the grain. The difference in grain Cu accumulation is most likely attributed to a single amino acid substitution that leads to different OsHMA4 transport activity. The allele associated with low grain Cu was found in 67 of the 1,367 rice accessions investigated. Identification of natural allelic variation in OsHMA4 may facilitate the development of rice varieties with grain Cu concentrations tuned to both the concentration of Cu in the soil and dietary needs.
キーワード Genetic variation Natural variation in plants Quantitative trait Rice
備考 This is an article published by Nature Publishing Group
発行日 2016-07
出版物タイトル Nature Communications
7巻
出版者 Nature Publishing Group
開始ページ 12138
ISSN 2041-1723
NCID AA12645905
資料タイプ 学術雑誌論文
言語 English
OAI-PMH Set 岡山大学
著作権者 https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
論文のバージョン publisher
PubMed ID 27387148
DOI 10.1038/ncomms12138
Web of Sience KeyUT 000380305000001
関連URL https://doi.org/10.1038/ncomms12138
著者 Miyaji, Takaaki| Kuromori, Takashi| Takeuchi, Yu| Yamaji, Naoki| Yokosho, Kengo| Shimazawa, Atsushi| Sugimoto, Eriko| Omote, Hiroshi| Ma, Jian Feng| Shinozaki, Kazuo| Moriyama, Yoshinori|
発行日 2015-01-05
出版物タイトル Nature Communications
6巻
資料タイプ 学術雑誌論文