ID | 53138 |
フルテキストURL | |
著者 |
Kanzaki, Hiromitsu
Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences
ORCID
publons
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Uedo, Noriya
Department of Gastrointestinal Oncology, Osaka Medical Center for Cancer and Cardiovascular Diseases
Ishihara, Ryu
Department of Gastrointestinal Oncology, Osaka Medical Center for Cancer and Cardiovascular Diseases
Nagai, Kengo
Department of Gastrointestinal Oncology, Osaka Medical Center for Cancer and Cardiovascular Diseases
Matsui, Fumi
Department of Gastrointestinal Oncology, Osaka Medical Center for Cancer and Cardiovascular Diseases
Ohta, Takashi
Department of Gastrointestinal Oncology, Osaka Medical Center for Cancer and Cardiovascular Diseases
Hanafusa, Masao
Department of Gastrointestinal Oncology, Osaka Medical Center for Cancer and Cardiovascular Diseases
Hanaoka, Noboru
Department of Gastrointestinal Oncology, Osaka Medical Center for Cancer and Cardiovascular Diseases
Takeuchi, Yoji
Department of Gastrointestinal Oncology, Osaka Medical Center for Cancer and Cardiovascular Diseases
Higashino, Koji
Department of Gastrointestinal Oncology, Osaka Medical Center for Cancer and Cardiovascular Diseases
Iishi, Hiroyasu
Department of Gastrointestinal Oncology, Osaka Medical Center for Cancer and Cardiovascular Diseases
Tomita, Yasuhiko
Department of Pathology, Osaka Medical Center for Cancer and Cardiovascular Diseases
Tatsuta, Masaharu
Department of Gastrointestinal Oncology, Osaka Medical Center for Cancer and Cardiovascular Diseases
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抄録 | Background: Barium radiographic studies have suggested the importance of evaluating areae gastricae pattern for the diagnosis of gastritis. Significance of endoscopic appearance of areae gastricae in the diagnosis of chronic atrophic fundic gastritis (CAFG) was investigated by image-enhanced endoscopy.
Materials and Methods: Endoscopic images of the corpus lesser curvature were studied in 50 patients with CAFG. Extent of CAFG was evaluated with autofluorescence imaging endoscopy. The areae gastricae pattern was evaluated with 0.2% indigo carmine chromoendoscopy. Micro-mucosal structure was examined with magnifying chromoendoscopy and narrow band imaging.
Results: In patients with small extent of CAFG, polygonal areae gastricae separated by a narrow intervening part of areae gastricae was observed, whereas in patients with wide extent of CAFG, the size of the areae gastricae decreased and the width of the intervening part of areae gastricae increased (p < 0.001). Most areae gastricae showed a foveola-type micro-mucosal structure (82.7%), while intervening part of areae gastricae had a groove-type structure (98.0%, p < 0.001). Groove-type mucosa had a higher grade of atrophy (p < 0.001) and intestinal metaplasia (p < 0.001) compared with foveola type.
Conclusions: As extent of CAFG widened, multifocal groove-type mucosa that had high-grade atrophy and intestinal metaplasia developed among areae gastricae and increased along the intervening part of areae gastricae. Our observations facilitate our understanding of the development and progression of CAFG.
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キーワード | Chronic atrophc fundic gastritis
image enhanced endoscopy
areae gastricae
magnified endoscopy
narrow band imaging
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備考 | This is the accepted version of the following article: FULLCITE, which has been published in final form at http://dx.doi.org/10.1111/j.1523-5378.2012.00938.x
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発行日 | 2012-06
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出版物タイトル |
Helicobacter
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巻 | 17巻
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号 | 3号
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開始ページ | 224
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終了ページ | 231
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資料タイプ |
学術雑誌論文
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関連URL | http://ousar.lib.okayama-u.ac.jp/metadata/53127
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言語 |
英語
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著作権者 | © 2012 Blackwell Publishing Ltd
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論文のバージョン | author
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査読 |
有り
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DOI |