ID | 62210 |
フルテキストURL | |
著者 |
Yoshinaga, Kasumi
Department of Urology, Graduate School of Medicine, Dentistry and Pharmaceutical Science, Okayama University
Araki, Motoo
Department of Urology, Graduate School of Medicine, Dentistry and Pharmaceutical Science, Okayama University
ORCID
Kaken ID
publons
researchmap
Wada, Koichiro
Department of Urology, Graduate School of Medicine, Dentistry and Pharmaceutical Science, Okayama University
ORCID
researchmap
Sekito, Takanori
Department of Urology, Graduate School of Medicine, Dentistry and Pharmaceutical Science, Okayama University
Watari, Shogo
Department of Urology, Graduate School of Medicine, Dentistry and Pharmaceutical Science, Okayama University
Maruyama, Yuki
Department of Urology, Graduate School of Medicine, Dentistry and Pharmaceutical Science, Okayama University
Mitsui, Yosuke
Department of Urology, Graduate School of Medicine, Dentistry and Pharmaceutical Science, Okayama University
Sadahira, Takuya
Department of Urology, Graduate School of Medicine, Dentistry and Pharmaceutical Science, Okayama University
Kubota, Risa
Department of Urology, Graduate School of Medicine, Dentistry and Pharmaceutical Science, Okayama University
Nishimura, Shingo
Department of Urology, Graduate School of Medicine, Dentistry and Pharmaceutical Science, Okayama University
Edamura, Kohei
Department of Urology, Graduate School of Medicine, Dentistry and Pharmaceutical Science, Okayama University
Kobayashi, Yasuyuki
Department of Urology, Graduate School of Medicine, Dentistry and Pharmaceutical Science, Okayama University
ORCID
Kaken ID
Tanabe, Katsuyuki
Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Graduate School of Medicine, Dentistry and Pharmaceutical Science, Okayama University
ORCID
Kaken ID
publons
researchmap
Takeuchi, Hidemi
Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Graduate School of Medicine, Dentistry and Pharmaceutical Science, Okayama University
Kitagawa, Masashi
Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Graduate School of Medicine, Dentistry and Pharmaceutical Science, Okayama University
Kaken ID
Kitamura, Shinji
Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Graduate School of Medicine, Dentistry and Pharmaceutical Science, Okayama University
Kaken ID
publons
Wada, Jun
Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Graduate School of Medicine, Dentistry and Pharmaceutical Science, Okayama University
ORCID
Kaken ID
publons
researchmap
Watanabe, Masami
Department of Urology, Graduate School of Medicine, Dentistry and Pharmaceutical Science, Okayama University
Kaken ID
publons
researchmap
Watanabe, Toyohiko
Department of Urology, Graduate School of Medicine, Dentistry and Pharmaceutical Science, Okayama University
Nasu, Yasutomo
Department of Urology, Graduate School of Medicine, Dentistry and Pharmaceutical Science, Okayama University
Kaken ID
publons
researchmap
|
抄録 | Objectives: To compare the donor outcomes of living donor kidney transplantation between standard donors (SDs) and marginal donors (MDs) including diabetic patients (MD + DM).
Methods: MDs were defined according to Japanese guideline criteria: (a) age >70-years, (b) blood pressure <= 130/80 mmHg on hypertension medicine, (c) body mass index >25 to <= 32 kg/m(2), (d) 24-h creatinine clearance >= 70 to <80 ml/min/1.73 m(2), and (e) hemoglobin A1c > 6.2 or <= 6.5 with oral diabetic medicine. Fifty-three of 114 donors were MDs. We compared donor kidney functions until 60 months postoperatively. Results: No kidney function parameters were different between SDs and MDs. When comparing SD and MD + DM, MD + DM had a lower postoperative eGFR (48 vs. 41 (1 (month), p = .02), 49 vs. 40 (12, p < .01), 48 vs. 42 (24, p = .04), 47 vs. 38 (36, p = .01)) and the percentage of residual eGFR (SD vs. MD + DM: 63 vs. 57 (1 (month), p < .01), 63 vs. 57 (2, p < .01), 64 vs. 56 (12, p < .01), 63 vs. 57 (24, p < .01), 63 vs. 52 (36, p = .02)). However, when MD with a single risk factor of DM was compared to SD, the difference disappeared. Nine out of 12 (75%) MD + DM had >= 2 risk factors. Conclusions: Although long-term observation of donor kidney function is necessary, careful MD + DM selection had the potential to expand the donor pool. |
キーワード | diabetes mellitus
kidney function
kidney transplantation
marginal donor
|
発行日 | 2021-06-08
|
出版物タイトル |
Immunity Inflammation and Disease
|
出版者 | Wiley
|
ISSN | 2050-4527
|
資料タイプ |
学術雑誌論文
|
言語 |
英語
|
OAI-PMH Set |
岡山大学
|
著作権者 | © 2021 The Authors.
|
論文のバージョン | publisher
|
PubMed ID | |
NAID | |
DOI | |
Web of Science KeyUT | |
関連URL | isVersionOf https://doi.org/10.1002/iid3.470
|
ライセンス | https://creativecommons.org/licenses/by/4.0/
|