ID | 65006 |
フルテキストURL | |
著者 |
Tominaga, Yusuke
Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Fujii, Masanori
Department of Allergy and Respiratory Medicine, Okayama University Hospital
Sadahira, Takuya
Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
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Katayama, Satoshi
Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Iwata, Takehiro
Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
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Nishimura, Shingo
Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Bekku, Kensuke
Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Edamura, Kohei
Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Kobayashi, Tomoko
Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Kobayashi, Yasuyuki
Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
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Kiura, Katsuyuki
Department of Allergy and Respiratory Medicine, Okayama University Hospital
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Maeda, Yoshinobu
Department of Allergy and Respiratory Medicine, Okayama University Hospital
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Wada, Koichiro
Department of Urology, Shimane University Faculty of Medicine
Araki, Motoo
Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
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抄録 | Intravesical immunotherapy using bacillus Calmette‑Guérin (BCG) is recommended for patients with intermediate‑ to high‑risk non‑muscle invasive bladder cancer. Bladder tuberculosis (TB) is a rare complication of BCG therapy. The present study describes the case of a 73‑year‑old man who underwent intravesical BCG therapy for urothelial carcinoma in situ of the bladder. Red patches around the resection scar were first detected 1 year and 5 months after BCG treatment; these findings gradually spread to encompass more of the bladder wall. Transurethral biopsy revealed a benign lesion, but the patient developed bilateral hydronephrosis and mild voiding dysfunction. The patient was eventually diagnosed with bladder TB by mycobacterial urine culture and TB‑specific polymerase chain reaction (PCR). The patient was given multidrug therapy (isoniazid, rifampicin and ethambutol) and their bladder TB was completely cured; however, their voiding dysfunction and bilateral hydronephrosis did not fully improve. Bladder TB can occur long after intravesical BCG administration and cystoscopy findings consistent with inflammation can be the key to suspecting this condition. Acid‑fast examination and PCR testing of a urine sample are necessary for early diagnosis.
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キーワード | bladder tuberculosis
bacillus Calmette-Guerin
bladder cancer
ureteral stricture
voiding dysfunction
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発行日 | 2022-12-20
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出版物タイトル |
Molecular and Clinical Oncology
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巻 | 18巻
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号 | 2号
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出版者 | Spandidos Publications
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開始ページ | 7
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ISSN | 2049-9450
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資料タイプ |
学術雑誌論文
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言語 |
英語
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OAI-PMH Set |
岡山大学
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著作権者 | © Tominaga et al.
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論文のバージョン | publisher
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PubMed ID | |
DOI | |
Web of Science KeyUT | |
関連URL | isVersionOf https://doi.org/10.3892/mco.2022.2603
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ライセンス | https://creativecommons.org/licenses/by-nc-nd/4.0/
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Citation | Tominaga Y, Fujii M, Sadahira T, Katayama S, Iwata T, Nishimura S, Bekku K, Edamura K, Kobayashi T, Kobayashi Y, Kobayashi Y, et al: Bladder tuberculosis with ureteral strictures after bacillus Calmette‑Guérin therapy for urinary bladder cancer: A case report. Mol Clin Oncol 18: 7, 2023
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