ID | 57385 |
フルテキストURL | |
著者 |
Kaneta, Takashi
Department of Chemistry, Graduate School of Natural Science and Technology, Okayama University
ORCID
Kaken ID
publons
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抄録 | Laser-induced fluorometry (LIF) has achieved the detection of single molecules, which ranks it among the most sensitive of detection techniques, whereas capillary electrophoresis (CE) is known as a powerful separation method with resolution that is beyond the reach of many other types of chromatography. Therefore, a coupling of LIF with CE has established an unrivaled analytical technique in terms of sensitivity and resolution. CE-LIF has demonstrated excellent performance in bioanalytical chemistry for the high-resolution separation and highly sensitive detection of DNAs, proteins, and small bioactive molecules. This review describes the CE-LIF methods developed by the author's group that include indirect and direct detection using diode lasers, post-column derivatization, and Hadamard transformation, as well as applications to the binding assays of specific DNA immunoassays of proteins and to the determination of anticancer drugs.
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キーワード | DNA sequencing
capillary electrophoresis
laser-induced fluorescence
micellar electrokinetic chromatography
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発行日 | 2018-08-06
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出版物タイトル |
Chemical Record
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巻 | 19巻
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号 | 2-3号
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出版者 | Wiley
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開始ページ | 452
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終了ページ | 461
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ISSN | 15278999
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NCID | AA11515019
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資料タイプ |
学術雑誌論文
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言語 |
英語
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OAI-PMH Set |
岡山大学
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論文のバージョン | author
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関連URL | isVersionOf https://doi.org/10.1002/tcr.201800051
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