フルテキストURL K0005280_fulltext.pdf
著者 Ishigami, Shuta| Ohtsuki, Shinichi| Tarui, Suguru| Ousaka, Daiki| Eitoku, Takahiro| Kondo, Maiko| Okuyama, Michihiro| Kobayashi, Junko| Baba, Kenji| Arai, Sadahiko| Kawabata, Takuya| Yoshizumi, Ko| Tateishi, Atsushi| Kuroko, Yosuke| Iwasaki, Tatsuo| Sato, Shuhei| Kasahara, Shingo| Sano, Shunji| Oh, Hidemasa|
キーワード cell therapy congenital heart disease hypoplastic left heart syndrome stem cells
備考 学位審査副論文
発行日 2015-02
出版物タイトル Circulation Research
116巻
4号
出版者 Lippincott Williams & Wilkins
開始ページ 653
終了ページ 664
ISSN 00097330
NCID AA00133553
資料タイプ 学術雑誌論文
言語 English
OAI-PMH Set 岡山大学
著作権者 https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
論文のバージョン author
PubMed ID 25403163
Web of Sience KeyUT 000349804900015
関連URL https://doi.org/10.1161/CIRCRESAHA.116.304671 http://ousar.lib.okayama-u.ac.jp/54044 http://ousar.lib.okayama-u.ac.jp/54263
JaLCDOI 10.18926/AMO/54809
フルテキストURL 70_6_461.pdf
著者 Shiozaki, Kyoko| Morimatsu, Hiroshi| Matsusaki, Takashi| Iwasaki, Tatsuo|
抄録 Many patients suffer from postoperative serious adverse events (SAEs). Here we sought to determine the incidence of SAEs, assess the accuracy of currently used scoring systems in predicting postoperative SAEs, and determine whether a combination of scoring systems would better predict postoperative SAEs. We prospectively evaluated patients who underwent major surgery. We calculated 4 scores: American Society of Anesthesiologists physical status (ASA-PS) score, the Charlson Score, the POSSUM (Physiological and Operative Severity Score for the enUmeration of Mortality and morbidity) score, and the Surgical Apgar Score (SAS). We assessed the occurrence of SAEs. We assessed the association between each score and SAEs. We combined these scoring systems to find the best combination to predict the occurrence of SAEs. Among 284 patients, 43 suffered SAEs. All scoring systems could predict SAEs. However, their predictive power was not high (the area under the receiver operating characteristic curves [AUROC] 0.6-0.7). A combination of the ASA-PS score and the SAS was the most predictive of postoperative SAEs (AUROC 0.714). The incidence of postoperative SAEs was 15.1 . The combination of the ASA-PS score and the SAS may be a useful tool for predicting postoperative serious adverse events after major surgery.
キーワード serious adverse events preoperative assessment intraoperative assessment ASA-PS surgical Apgar score
Amo Type Original Article
発行日 2016-12
出版物タイトル Acta Medica Okayama
70巻
6号
出版者 Okayama University Medical School
開始ページ 461
終了ページ 467
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
著作権者 CopyrightⒸ 2016 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 28003671
JaLCDOI 10.18926/AMO/31995
フルテキストURL fulltext.pdf
著者 Takeuchi, Mamoru| Morita, Kiyoshi| Iwasaki, Tatsuo| Toda, Yuichiro| Oe, Katsunori| Taga, Naoyuki| Hirakawa, Masahisa|
抄録 <p>To elucidate the effect of adrenomedullin (AM) on fluid homeostasis under cardiopulmonary bypass (CPB), we investigated the serial changes in plasma AM and other parameters related to fluid homeostasis in 13 children (average age, 28.2 months) with congenital heart disease during cardiac surgery under CPB. Arterial blood and urine samples were collected just after initiation of anesthesia, just before commencement of CPB, 10 min before the end of CPB, 60 min after CPB, and 24 h after operation. Plasma AM levels increased significantly 10 min before the end of CPB and decreased 24 h after operation. Urine volume increased transiently during CPB, which paralleled changes in AM. Simple regression analysis showed that plasma AM level correlated significantly with urinary vasopressin, urine volume, urinary sodium excretion, and plasma osmolarity. Stepwise regression analysis indicated that urine volume was the most significant determinant of plasma AM levels. Percent rise in AM during CPB relative to control period correlated with that of plasma brain natriuretic peptide (r = 0.57, P &#60; 0.01). Our results suggest that AM plays an important role in fluid homeostasis under CPB in cooperation with other hormones involved in fluid homeostasis.</p>
キーワード adrenomedullin cardiopulmonary bypass vasopressin pediatric cardiac surgery brain natriuretic peptide
Amo Type Article
発行日 2001-08
出版物タイトル Acta Medica Okayama
55巻
4号
出版者 Okayama University Medical School
開始ページ 245
終了ページ 252
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
論文のバージョン publisher
査読 有り
PubMed ID 11512567
Web of Sience KeyUT 000170367200007
著者 岩崎 達雄|
発行日 2006-06-30
出版物タイトル
資料タイプ 学位論文