| JaLCDOI | 10.18926/AMO/68356 |
|---|---|
| フルテキストURL | 79_1_031.pdf |
| 著者 | Maeda, Shigeru| Pimkhaokham, Atiphan| Yoshida, Michihiro| Hosoi, Hiroki| Ohshima, Ayako| Kurisu, Ryoko| Utsumi, Nozomi| Higuchi, Hitoshi| Miyawaki, Takuya| |
| 抄録 | We retrospectively analyzed the safety of the use of articaine, an amide-type local anesthetic, in Japanese dental patients (n=300) treated in Thailand in 2015-2017. The dosage, adverse events (AEs) caused by local anesthesia, and treatment efficacy were examined. Articaine, which is safe for patients with liver impairments due to its unique metabolism, has not been thoroughly tested in Japan for doses above 5.1 mL. Eighty of the present patients had undergone root canal treatment (RCT), 71 underwent tooth extraction, and 149 underwent implant-related surgery. More than three articaine cartridges were used in 41 patients, and no AEs occurred in these cases. The only AE occurred in a 52-year-old woman who was treated with three cartridges and presented with what appeared to be hyperventilation syndrome; she later recovered and received her dental treatment as scheduled. Most treatments were completed with three or fewer cartridges, suggesting that this number is generally sufficient. Our findings, particularly the low AE risk even with doses exceeding three cartridges, support the potential applicability of the overseas recommended maximum dose of articaine (7 mg/kg) in Japanese patients. This conclusion is significant for advancing dental anesthetic practices and ensuring patient safety and treatment efficacy in Japan. |
| キーワード | dental anesthesia local anesthesia drug-related side effect adverse reaction |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2025-02 |
| 巻 | 79巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 31 |
| 終了ページ | 37 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2025 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 40012157 |
| Web of Science KeyUT | 001440463800004 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Higuchi, Hitoshi| Miyake, Kota| Miyake, Saki| Fujimoto, Maki| Nishioka, Yukiko| Maeda, Shigeru| Miyawaki, Takuya| |
| キーワード | autism spectrum disorder intellectual disabilities oral midazolam premedication sedation |
| 発行日 | 2024-06-11 |
| 出版物タイトル | Journal of Applied Research in Intellectual Disabilities |
| 巻 | 37巻 |
| 号 | 4号 |
| 出版者 | Wiley |
| 開始ページ | e13265 |
| ISSN | 1360-2322 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2024 The Author(s). |
| 論文のバージョン | publisher |
| PubMed ID | 38859732 |
| DOI | 10.1111/jar.13265 |
| Web of Science KeyUT | 001242656000001 |
| 関連URL | isVersionOf https://doi.org/10.1111/jar.13265 |
| フルテキストURL | fulltext20210914-1.pdf figures20210914-1.pdf |
|---|---|
| 著者 | Higuchi, Hitoshi| Takaya-Ishida, Kumiko| Miyake, Saki| Fujimoto, Maki| Nishioka, Yukiko| Maeda, Shigeru| Miyawaki, Takuya| |
| 備考 | This is an Accepted Manuscript of an article published by Elsevier. © 2021 The American Association of Oral and Maxillofacial Surgeon. This manuscript version is made available under the CC-BY-NC-ND 4.0 License.http://creativecommons.org/licenses/by-nc-nd/4.0/.This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.joms.2021.04.004] .| |
| 発行日 | 2021-9 |
| 出版物タイトル | Journal of Oral and Maxillofacial Surgery |
| 巻 | 79巻 |
| 号 | 9号 |
| 出版者 | Elsevier BV |
| 開始ページ | 1842 |
| 終了ページ | 1850 |
| ISSN | 0278-2391 |
| NCID | AA10628202 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2021 The American Association of Oral and Maxillofacial Surgeon |
| 論文のバージョン | author |
| PubMed ID | 34022138 |
| DOI | 10.1016/j.joms.2021.04.004 |
| Web of Science KeyUT | 000691194500011 |
| 関連URL | https://doi.org/10.1016/j.joms.2021.04.004 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Kodama, Matsuri| Higuchi, Hitoshi| Ishii-Maruhama, Minako| Nakano, Mai| Honda-Wakasugi, Yuka| Maeda, Shigeru| Miyawaki, Takuya| |
| キーワード | Drug regulation Phase IV trials |
| 発行日 | 2020-01-31 |
| 出版物タイトル | Scientific Reports |
| 巻 | 10巻 |
| 号 | 1号 |
| 出版者 | Nature |
| 開始ページ | 1578 |
| ISSN | 2045-2322 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2020 |
| 論文のバージョン | publisher |
| PubMed ID | 32005870 |
| DOI | 10.1038/s41598-020-58460-2 |
| Web of Science KeyUT | 000562877500004 |
| 関連URL | isVersionOf https://doi.org/10.1038/s41598-020-58460-2 |
| フルテキストURL | AOB_98_38.pdf |
|---|---|
| 著者 | Tajiri, Ayako| Higuchi, Hitoshi| Miyawaki, Takuya| |
| キーワード | Hyperoxia Hyposalivation Oxidative stress Saliva |
| 発行日 | 2019-02-28 |
| 出版物タイトル | Archives of Oral Biology |
| 巻 | 98巻 |
| 出版者 | PERGAMON-ELSEVIER SCIENCE |
| 開始ページ | 38 |
| 終了ページ | 46 |
| ISSN | 00039969 |
| NCID | AA00548457 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2018 Elsevier Ltd. All rights reserved. |
| 論文のバージョン | author |
| PubMed ID | 30445238 |
| DOI | 10.1016/j.archoralbio.2018.11.001 |
| Web of Science KeyUT | 000457664000006 |
| 関連URL | isVersionOf https://doi.org/10.1016/j.archoralbio.2018.11.001 |
| JaLCDOI | 10.18926/AMO/52895 |
|---|---|
| フルテキストURL | 68_5_269.pdf |
| 著者 | Tomoyasu, Yumiko| Higuchi, Hitoshi| Mori, Megumi| Takaya, Kumiko| Honda, Yuka| Yamane, Ayaka| Yabuki, Akiko| Hayashi, Tomoko| Ishii-Maruhama, Minako| Jinzenji, Ayako| Maeda, Shigeru| Kohjitani, Atsushi| Shimada, Masahiko| Miyawaki, Takuya| |
| 抄録 | Orofacial pain is often difficult to diagnose and treat. However, there have been few reports on the clinical observation of dental patients with orofacial pain. We retrospectively investigated the characteristics of 221 dental patients who had suffered from persistent orofacial pain. Data were collected from the outpatient medical records in our clinic over the past 12 years. More than half of the patients (53.8%) had suffered with pain for more than 6 months from pain onset until the first visit to our clinic. The main diagnoses were neuropathic pain (30.3%), myofascial pain (23.5%), psychogenic pain (20.4%), odontogenic toothache (17.2%), and others (7.7%) such as temporomandibular disorders and glossitis. The treatments included pharmacotherapy, splint therapy, and others such as nerve block, dental treatment, physiotherapy, and/or psychotherapy. Excluding the patients (52 of 221 initially enrolled patients) with unknown responses to treatment, 65.7% showed remission or a significant improvement in pain in response to treatment. Although only a small group of patients had odontogenic toothache, the rate of improvement was highest for this disorder. In conclusion, early consultation with a dentist is useful to prevent chronicity of odontogenic pain and to make a differential diagnosis in patients with orofacial pain. |
| キーワード | dental patients pain clinic orofacial pain dental anesthesiology clinical observation |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2014-10 |
| 巻 | 68巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 269 |
| 終了ページ | 275 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2014 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 25338483 |
| Web of Science KeyUT | 000343269300003 |