| JaLCDOI |
10.18926/AMO/54810
|
| フルテキストURL |
70_6_469.pdf
|
| 著者 |
Yamasaki, Yasushi|
Takenaka, Ryuta|
Hori, Keisuke|
Takemoto, Koji|
Kawano, Seiji|
Kawahara, Yoshiro|
Fujiki, Shigeatsu|
Okada , Hiroyuki|
|
| 抄録 |
The usefulness of endoscopy in marginal ulcer bleeding has rarely been studied, and the optimal method for preventing rebleeding is unclear. Here we assessed the efficacy of endoscopy in marginal ulcer bleeding and examined the efficacy of proton pump inhibitors (PPIs) in the prevention of rebleeding. A total of 28 patients with marginal ulcer bleeding (21 men, 7 women; median age 58.5 years) were treated by endoscopy. We analyzed the clinical characteristics, results of endoscopic therapy, characteristics of rebleeding patients, and relation between the use of PPIs and the duration of rebleeding. Sixteen patients had active bleeding. Initial hemostasis was achieved in all patients. There were no procedure-related adverse events. Rebleeding occurred in one patient within the first month and in 7 patients thereafter. There was a significant difference in the rebleeding rate between the patients who received a PPI and those who did not. In a multivariate analysis, the non-use of PPIs was a risk factor for rebleeding (hazard ratio, 6.22). Therapeutic endoscopy is effective in achieving hemostasis from marginal ulcer bleeding. PPIs may prevent rebleeding from marginal ulcers.
|
| キーワード |
marginal ulcer
upper gastrointestinal bleeding
endoscopic hemostasis
proton-pump inhibitor
|
| Amo Type |
Original Article
|
| 出版物タイトル |
Acta Medica Okayama
|
| 発行日 |
2016-12
|
| 巻 |
70巻
|
| 号 |
6号
|
| 出版者 |
Okayama University Medical School
|
| 開始ページ |
469
|
| 終了ページ |
475
|
| ISSN |
0386-300X
|
| NCID |
AA00508441
|
| 資料タイプ |
学術雑誌論文
|
| 言語 |
英語
|
| 著作権者 |
CopyrightⒸ 2016 by Okayama University Medical School
|
| 論文のバージョン |
publisher
|
| 査読 |
有り
|
| PubMed ID |
28003672
|
