ID | 48962 |
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フルテキストURL | |
著者 |
Wang, Feifei
Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Maeda, Nagamasa
Center for Innovative and Translational Medicine, Kochi Medical School
Yasuhara, Takao
Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Kameda, Masahiro
Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Tsuru, Emi
Center for Innovative and Translational Medicine, Kochi Medical School
Yamashita, Tatsuyuki
Center for Innovative and Translational Medicine, Kochi Medical School
Shen, Yuan
Center for Innovative and Translational Medicine, Kochi Medical School
Tsuda, Masayuki
Center for Innovative and Translational Medicine, Kochi Medical School
Date, Isao
Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
ORCID
Kaken ID
publons
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Sagara, Yusuke
Center for Innovative and Translational Medicine, Kochi Medical School
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抄録 | Human umbilical cord blood (HUCB) cells are rich source of immature stem cells, which have the potential to repair lost tissue. Intractable central nervous system (CNS) disorders are important targets for regenerative medicine, and the application of HUCB cells is being investigated in animal models of CNS disorders. Transplantation of HUCB has induced functional improvements in these animal models due to multiple therapeutic effects including neuroprotection, anti-inflammation, angiogenesis, and neurogenesis. HUCB cells are easily available and safer than other stem cells used in transplantation therapy. In this review, we focus on HUCB transplantation as an encouraging therapeutic approach for animal models of neonatal hypoxic-ischemic brain injury and ischemic stroke.
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キーワード | umbilical cord blood
cell transplantation
neonatal hypoxic-ischemic brain injury
ischemic stroke
stem cells
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Amo Type | Review
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出版物タイトル |
Acta Medica Okayama
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発行日 | 2012-12
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巻 | 66巻
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号 | 6号
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出版者 | Okayama University Medical School
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開始ページ | 429
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終了ページ | 434
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ISSN | 0386-300X
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NCID | AA00508441
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資料タイプ |
学術雑誌論文
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言語 |
英語
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著作権者 | CopyrightⒸ 2012 by Okayama University Medical School
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論文のバージョン | publisher
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査読 |
有り
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