ID | 53646 |
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Tsuda, Toshihide
Graduate School of Environmental and Life Science, Okayama University
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Tokinobu, Akiko
Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
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Yamamoto, Eiji
Faculty of Informatics, Okayama University of Science
Suzuki, Etsuji
Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
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抄録 | Background: After the Great East Japan Earthquake and Tsunami in March 2011, radioactive elements were released from the Fukushima Daiichi Nuclear Power Plant. Based on prior knowledge, concern emerged about whether an increased incidence of thyroid cancer among exposed residents would occur as a result.
Methods: After the release, Fukushima Prefecture performed ultrasound thyroid screening on all residents ages <=18 years. The first round of screening included 298,577 examinees, and a second round began in April 2014. We analyzed the prefecture results from the first and second round up to December 31, 2014, in comparison with the Japanese annual incidence and the incidence within a reference area in Fukushima Prefecture.
Results: The highest incidence rate ratio, using a latency period of 4 years, was observed in the central middle district of the prefecture compared with the Japanese annual incidence (incidence rate ratio = 50; 95% confidence interval [CI] = 25, 90). The prevalence of thyroid cancer was 605 per million examinees (95% CI = 302, 1,082) and the prevalence odds ratio compared with the reference district in Fukushima Prefecture was 2.6 (95% CI = 0.99, 7.0). In the second screening round, even under the assumption that the rest of examinees were disease free, an incidence rate ratio of 12 has already been observed (95% CI = 5.1, 23).
Conclusions: An excess of thyroid cancer has been detected by ultrasound among children and adolescents in Fukushima Prefecture within 4 years of the release, and is unlikely to be explained by a screening surge.
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備考 | This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially.
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発行日 | 2015
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出版物タイトル |
Epidemiology
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出版者 | International Society for Environmental Epidemiology
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ISSN | 1044-3983
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NCID | AA10832184
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資料タイプ |
学術雑誌論文
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オフィシャル URL | http://dx.doi.org/10.1097/EDE.0000000000000385
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言語 |
英語
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著作権者 | Copyright (C) 2015 Wolters Kluwer Health
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論文のバージョン | publisher
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査読 |
有り
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