| ID | 52810 |
| フルテキストURL | |
| 著者 |
Tomofuji, Takaaki
Okayama Univ, Sch Med Dent & Pharmaceut Sci, Dept Prevent Dent
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Kawabata, Yuya
Okayama Univ, Sch Med Dent & Pharmaceut Sci, Dept Prevent Dent
Kasuyama, Kenta
Okayama Univ, Sch Med Dent & Pharmaceut Sci, Dept Prevent Dent
Endo, Yasumasa
Okayama Univ, Sch Med Dent & Pharmaceut Sci, Dept Prevent Dent
Yoneda, Toshiki
Okayama Univ, Sch Med Dent & Pharmaceut Sci, Dept Prevent Dent
Yamane, Mayu
Okayama Univ, Sch Med Dent & Pharmaceut Sci, Dept Prevent Dent
Azuma, Tetsuji
Okayama Univ, Sch Med Dent & Pharmaceut Sci, Dept Prevent Dent
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Ekuni, Daisuke
Okayama Univ, Sch Med Dent & Pharmaceut Sci, Dept Prevent Dent
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Morita, Manabu
Okayama Univ, Sch Med Dent & Pharmaceut Sci, Dept Prevent Dent
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| 抄録 | Oxidative damage is involved in age-related inflammatory reactions. The anti-oxidative effects of hydrogen-rich water suppress oxidative damage, which may aid in inhibiting age-related inflammatory reactions. We investigated the effects of drinking hydrogen-rich water on aging periodontal tissues in healthy rats. Four-month-old male Fischer 344 rats (n = 12) were divided into two groups: the experimental group (hydrogen-rich water treatment) and the control group (distilled water treatment). The rats consumed hydrogen-rich water or distilled water until 16 months of age. The experimental group exhibited lower periodontal oxidative damage at 16 months of age than the control group. Although protein expression of interleukin-1 beta did not differ, gene expression of Nod-like receptor protein 3 inflammasomes was activated in periodontal tissues from the experimental group as compared with the control group. Drinking hydrogen-rich water is proposed to have anti-aging effects on periodontal oxidative damage, but not on inflammatory reactions in healthy rats.
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| 発行日 | 2014-07-02
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| 出版物タイトル |
Scientific Reports
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| 巻 | 4巻
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| ISSN | 2045-2322
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| 資料タイプ |
学術雑誌論文
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| 言語 |
英語
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| 著作権者 | This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder in order to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
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| 論文のバージョン | publisher
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| 査読 |
有り
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| DOI | |
| Web of Science KeyUT |
