ID | 60370 |
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Isoyama, Satoshi
Department of Anesthesiology and Resuscitation, Okayama University Hospital
Kimura, Satoshi
Department of Anesthesiology and Resuscitation, Okayama University Hospital
Morimatsu, Hiroshi
Department of Anesthesiology and Resuscitation, Okayama University Hospital
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抄録 | Little is known about the role of a strong ions in humans with respiratory abnormalities. In this study, we investigated the associations between partial carbon dioxide pressure (pCO2) and each of sodium ion (Na+) concentrations, chloride ion (Cl−) concentrations and their difference (SIDNa-Cl). Blood gas data were obtained from patients in a teaching hospital intensive care unit between August 2013 and January 2017. The association between pCO2 and SIDNa-Cl was defined as the primary outcome. The associations between pCO2 and [Cl−], [Na+] and other strong ions were secondary outcomes. pCO2 was stratified into 10 mmHg-wide bands and treated as a categorical variable for comparison. As a result, we reviewed 115,936 blood gas data points from 3,840 different ICU stays. There were significant differences in SIDNa-Cl, [Cl−], and [Na+] among all categorized pCO2 bands. The respective pCO2 SIDNa-Cl, [Cl−], and [Na+] correlation coefficients were 0.48, −0.31, and 0.08. SIDNa-Cl increased and [Cl−] decreased with pCO2, with little relationship between pCO2 and [Na+] across subsets. In conclusion, we found relatively strong correlations between pCO2 and SIDNa-Cl in the multiple blood gas datasets examined. Correlations between pCO2 and chloride concentrations, but not sodium concentrations, were further found to be moderate in these ICU data.
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キーワード | acid-base phenomena
Stewart approach
strong ion difference
chlorine ion
partial carbon dioxide pressure
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Amo Type | Original Article
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出版物タイトル |
Acta Medica Okayama
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発行日 | 2020-08
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巻 | 74巻
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号 | 4号
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出版者 | Okayama University Medical School
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開始ページ | 319
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終了ページ | 325
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ISSN | 0386-300X
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NCID | AA00508441
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資料タイプ |
学術雑誌論文
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言語 |
英語
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著作権者 | CopyrightⒸ 2020 by Okayama University Medical School
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論文のバージョン | publisher
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査読 |
有り
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