| ID | 67681 |
| 著者 |
Matoba, Ryo
Department of Ophthalmology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
Kanzaki, Yuki
Department of Ophthalmology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
Morita, Tetsuro
Department of Ophthalmology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
Masuda, Yuki
Department of Ophthalmology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
Kimura, Shuhei
Department of Ophthalmology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
ORCID
Kaken ID
Hosokawa, Mio M.
Department of Ophthalmology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
Shiode, Yusuke
Department of Ophthalmology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
Kaken ID
|
| 抄録 | Purpose: To investigate the characteristics of mixed pathophysiologies in lamellar macular holes (LMHs) and related diseases using multimodal optical coherence tomography.
Methods: Overall, 126 eyes diagnosed with LMH, epiretinal membrane foveoschisis, or macular pseudohole using the horizontal B-scan image according to the definition proposed by Hubschman et al in 2020 were analyzed using multimodal optical coherence tomography imaging including horizontal and vertical 5-line B-scan, radial scan, and macular three-dimensional volume scan images. If at least two diagnostic criteria for LMH, epiretinal membrane foveoschisis, or macular pseudohole were satisfied in these scans, the patient was diagnosed as having a “mixed type.” Retinal traction force was quantitatively evaluated by measuring the maximum depth of the retinal folds using en-face images. Results: Mixed types constituted 34.1% of the cases. The LMH-related mixed group demonstrated intermediate characteristics between the epiretinal membrane foveoschisis/macular pseudohole and true LMH groups in terms of retinal traction and LMH-specific features and had a significant positive correlation between the maximum depth of the retinal folds and mean M-CHARTS scores (P = 0.034). Conclusion: A thorough optical coherence tomography analysis is necessary to accurately diagnose LMH and related diseases. A significant positive correlation was observed between the maximum depth of the retinal folds and the degree of metamorphopsia in the LMH-related mixed group. |
| キーワード | en-face imaging
epiretinal membrane
epiretinal membrane foveoschisis
lamellar macular hole
metamorphopsia
mixed type
optical coherence tomography
retinal fold
retinal traction
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| 備考 | This is a non-final version of an article published in final form in Matoba, Ryo MD, PhD; Kanzaki, Yuki MD, PhD; Morita, Tetsuro MD; Masuda, Yuki MD; Kimura, Shuhei MD, PhD; Hosokawa, Mio M. MD, PhD; Shiode, Yusuke MD, PhD; Morizane, Yuki MD, PhD. MIXED PATHOPHYSIOLOGIES OF LAMELLAR MACULAR HOLES AND RELATED DISEASES: A Multimodal Optical Coherence Tomography–Based Study. Retina 44(10):p 1785-1792, October 2024. | DOI: 10.1097/IAE.0000000000004166.
This fulltext file will be available in Oct. 2025.
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| 発行日 | 2024-10
|
| 出版物タイトル |
Retina
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| 巻 | 44巻
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| 号 | 10号
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| 出版者 | Ovid Technologies (Wolters Kluwer Health)
|
| 開始ページ | 1785
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| 終了ページ | 1792
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| ISSN | 0275-004X
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| NCID | AA10639923
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| 資料タイプ |
学術雑誌論文
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| 言語 |
英語
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| OAI-PMH Set |
岡山大学
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| 著作権者 | © 2024, Wolters Kluwer Health
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| 論文のバージョン | author
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| PubMed ID | |
| DOI | |
| Web of Science KeyUT | |
| 関連URL | isVersionOf https://doi.org/10.1097/iae.0000000000004166
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| Citation | Matoba, Ryo MD, PhD; Kanzaki, Yuki MD, PhD; Morita, Tetsuro MD; Masuda, Yuki MD; Kimura, Shuhei MD, PhD; Hosokawa, Mio M. MD, PhD; Shiode, Yusuke MD, PhD; Morizane, Yuki MD, PhD. MIXED PATHOPHYSIOLOGIES OF LAMELLAR MACULAR HOLES AND RELATED DISEASES: A Multimodal Optical Coherence Tomography–Based Study. Retina 44(10):p 1785-1792, October 2024. | DOI: 10.1097/IAE.0000000000004166
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