ID | 62710 |
フルテキストURL | |
著者 |
Kamada, Yasuhiko
Department of Obstetrics and Gynecology Okayama University Hospital
ORCID
Kaken ID
publons
researchmap
Kusumoto, Rie
Department of Obstetrics and Gynecology Okayama University Hospital
Kashino, Chiaki
Department of Obstetrics and Gynecology Okayama University Hospital
Kubo, Kotaro
Department of Obstetrics and Gynecology Okayama University Hospital
Mitsui, Takashi
Department of Obstetrics and Gynecology Okayama University Hospital
Masuyama, Hisashi
Department of Obstetrics and Gynecology Okayama University Hospital
Kaken ID
publons
researchmap
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抄録 | Hematopoietic stem cell transplantation (HSCT) is a crucial treatment for hematological malignancy. Gonadal dysfunction occurs at an early stage after this treatment, and such patients may require hormone replacement therapy. Genital chronic graft-versus-host disease is a lesser-known complication of HSCT that begins with vulvar discomfort and dysuria and progresses to sexual dysfunction and retention of menstrual blood due to vaginal stenosis and obstruction; thus, significantly impairing the patient's quality of life. We describe three women who underwent vaginal reconstruction because of genital chronic graft-versus-host disease. We discuss the surgical techniques, including double cross plasty that were performed in each case. Surgical interventions enabled the continuation of HRT and facilitated sexual intercourse. In conclusion, gynecologists should be aware that genital chronic graft-versus-host disease can occur after HSCT, and that surgical treatment options are available to improve patients' symptoms and quality of life.
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キーワード | double cross plasty
genital chronic graft-versus-host disease
hematocolpos
hematopoietic stem cell transplantation
vaginal reconstruction
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備考 | This is the peer reviewed version of the following article: [Kamada, Y., Kusumoto, R., Kashino, C., Kubo, K., Mitsui, T., & Masuyama, H. (2021). Surgically treated genital chronic graft‐versus‐host disease in women: A report of three cases. Journal of Obstetrics and Gynaecology Research.], which has been published in final form at [https://doi.org/10.1111/jog.15005]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-ArchivedVersions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wileyor by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked toWiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof bythird parties from platforms, services and websites other than Wiley Online Library must be prohibited.
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発行日 | 2021-09-05
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出版物タイトル |
Journal of Obstetrics and Gynaecology Research
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巻 | 47巻
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号 | 11号
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出版者 | Wiley
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開始ページ | 4122
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終了ページ | 4126
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ISSN | 1341-8076
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NCID | AA11082002
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資料タイプ |
学術雑誌論文
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言語 |
英語
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OAI-PMH Set |
岡山大学
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著作権者 | © 2021 Japan Society of Obstetrics and Gynecology
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論文のバージョン | author
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PubMed ID | |
DOI | |
Web of Science KeyUT | |
関連URL | isVersionOf https://doi.org/10.1111/jog.15005
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Citation | Kamada, Y., Kusumoto, R., Kashino, C., Kubo, K., Mitsui, T., & Masuyama, H. (2021). Surgically treated genital chronic graft‐versus‐host disease in women: A report of three cases. Journal of Obstetrics and Gynaecology Research.
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