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ID 62789
フルテキストURL
著者
Hisano, Hiroshi Institute of Plant Science and Resources, Okayama University ORCID Kaken ID publons researchmap
Abe, Fumitaka Institute of Crop Science, National Agriculture and Food Research Organization
Hoffie, Robert E. Leibniz Institute of Plant Genetics and Crop Plant Research (IPK)
Kumlehn, Jochen Leibniz Institute of Plant Genetics and Crop Plant Research (IPK)
抄録
The recent advent of customizable endonucleases has led to remarkable advances in genetic engineering, as these molecular scissors allow for the targeted introduction of mutations or even precisely predefined genetic modifications into virtually any genomic target site of choice. Thanks to its unprecedented precision, efficiency, and functional versatility, this technology, commonly referred to as genome editing, has become an effective force not only in basic research devoted to the elucidation of gene function, but also for knowledgebased improvement of crop traits. Among the different platforms currently available for site-directed genome modifications, RNA-guided clustered regularly interspaced short palindromic repeats (CRISPR)-associated (Cas) endonucleases have proven to be the most powerful. This review provides an application-oriented overview of the development of customizable endonucleases, current approaches to cereal crop breeding, and future opportunities in this field.
キーワード
barley
CRISPR
maize
rice
TALEN
wheat
zinc-finger nucleases
備考
出典:Breeding Science 71(4) 405-416, 2021 https://doi.org/10.1270/jsbbs.21019
許可を得て出版社版を登録しています。
発行日
2021-10-01
出版物タイトル
Breeding Science
71巻
4号
出版者
Japanese Society of Breeding
開始ページ
405
終了ページ
416
ISSN
1344-7610
資料タイプ
学術雑誌論文
言語
英語
OAI-PMH Set
岡山大学
著作権者
(C) 2021 Japanese Society of Breeding
論文のバージョン
publisher
DOI
関連URL
isVersionOf https://doi.org/10.1270/jsbbs.21019
Citation
Hiroshi Hisano, Fumitaka Abe, Robert E. Hoffie, Jochen Kumlehn, Targeted genome modifications in cereal crops, Breeding Science, 2021, Volume 71, Issue 4, Pages 405-416