| ID | 52866 |
| フルテキストURL | |
| 著者 |
Yamamoto, Hiroshi
Shujitsu Univ, Sch Pharm
|
| 抄録 | The key precursor, N-2-(N,N -dimethylaminomethylene)-6-hydroxymethyl-8-methyl-3-[2-(4-nitrophenyl)ethyl]-7-xanthopterin (16) was efficiently prepared from 2,5-diamino-6-methylamino-3H-pyrimidin-4-one (5) and ethyl 3-(tert-butyldimethylsilyloxy)-2-oxopropionate (12), followed by the protection of the pteridine ring. Glycosylation of 16 with 1-O-acetyl-2,3,5-tri-O-benzoyl-beta-D-ribofuranose (18) in the presence of tin(IV) chloride yielded the corresponding beta-D-ribofuranoside. Successive removal of the protecting groups of the resulting D-ribofuranoside provided asperopterin A (4b).
|
| キーワード | asperopterin
glycosylation
isoxanthopterin
protecting groups
pterin glycoside
|
| 備考 | “The final publication is available at www.degruyter.com”.
|
| 発行日 | 2013-06
|
| 出版物タイトル |
Pteridines
|
| 巻 | 24巻
|
| 号 | 1号
|
| 出版者 | International Society of Pteridinology
|
| 開始ページ | 3
|
| 終了ページ | 6
|
| ISSN | 0933-4807
|
| 資料タイプ |
学術雑誌論文
|
| 言語 |
英語
|
| 著作権者 | © International Society of Pteridinology
|
| 論文のバージョン | publisher
|
| 査読 |
有り
|
| DOI | |
| Web of Science KeyUT |
