ID | 34204 |
フルテキストURL | |
著者 |
Hanaya, Tadashi
Department of Chemistry, Faculty of Science, Okayama University
Kaken ID
publons
researchmap
Nakamura, Yuichi
Department of Chemistry, Faculty of Science, Okayama University
Yamamoto, Hiroshi
Department of Chemistry, Faculty of Science, Okayama University
|
抄録 | (R)-2-Tosyloxypropanal (4) was prepared from D-mannitol in a 7-step sequence (51% overall yield). Addition of dialkyl phosphonates to 4 in the presence of titanium isopropoxide and the subsequent treatment with DBU stereoselectively afforded, in one-pot, fosfomycin dimethyl (5a) and dibenzyl (5b) esters both in 58% isolated yield.
|
キーワード | Fosfomycin
Epoxidation
C-P Bond Formation
Phosphonate Addition
Diastereoselectivity
|
発行日 | 2007-12-31
|
出版物タイトル |
Heterocycles
|
巻 | 74巻
|
号 | 1号
|
出版者 | The Japan Institute of Heterocyclic Chemistry
|
開始ページ | 983
|
終了ページ | 989
|
ISSN | 1881-0942
|
資料タイプ |
学術雑誌論文
|
オフィシャル URL | http://dx.doi.org/10.3987/COM-07-S(W)45
|
言語 |
英語
|
著作権者 | © The Japan Institute of Heterocyclic Chemistry
|
論文のバージョン | author
|
査読 |
有り
|
DOI | |
Web of Science KeyUT | |
Submission Path | organic_chemistry/6
|