ID | 63348 |
フルテキストURL | |
著者 |
Silangcruz, Krixie
Department of Internal Medicine, University of Hawai’i
Nishimura, Yoshito
Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
ORCID
publons
researchmap
Czech, Torrey
Department of Internal Medicine, University of Hawai’i
Kimura, Nobuhiko
Department of Internal Medicine, University of Hawai’i
Yess, James
Department of Internal Medicine, University of Hawai’i
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抄録 | Serum procalcitonin (PCT) has been reported as a potential biomarker to predict the severity of acute cholangitis (AC) or the need for urgent biliary decompression. This study aimed to identify and summarize the existing research about serum PCT and the severity of AC, and to find gaps towards which future studies can be targeted. Following the PRISMA extension for scoping reviews, MEDLINE, EMBASE, and Google Scholar were searched for all peer-reviewed articles with relevant keywords including "cholangitis" and "procalcitonin" from their inception to 13 July 2021. We identified six studies. All the studies employed a case-control design and aimed to evaluate the usefulness of serum PCT to predict the severity of AC with key identified outcomes. While the potential cut-off values of serum PCT for severe AC ranged from 1.8-3.1 ng/mL, studies used different severity criteria and the definition of urgent biliary decompression. No studies proposed cut-off PCT values for the need for urgent biliary decompression. This scoping review identified the current level of evidence regarding the usefulness of serum PCT in assessing the severity of AC. Further clinical research is warranted with a focus on standardized outcome measures employing prospective or experimental designs.
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キーワード | procalcitonin
acute cholangitis
scoping review
systematic review
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発行日 | 2022-02-22
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出版物タイトル |
Journal Of Clinical Medicine
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巻 | 11巻
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号 | 5号
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出版者 | MDPI
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開始ページ | 1155
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ISSN | 2077-0383
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資料タイプ |
学術雑誌論文
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言語 |
英語
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OAI-PMH Set |
岡山大学
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著作権者 | © 2022 by the authors.
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論文のバージョン | publisher
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PubMed ID | |
DOI | |
Web of Science KeyUT | |
関連URL | isVersionOf https://doi.org/10.3390/jcm11051155
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ライセンス | https://creativecommons.org/licenses/by/4.0/
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