| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Iwamuro, Masaya| Miyahara, Koji| Sakaguchi, Chihiro| Takenaka, Ryuta| Kobayashi, Sayo| Mouri, Hirokazu| Tanaka, Shigetomi| Toyokawa, Tatsuya| Tanaka, Shouichi| Nishimura, Mamoru| Yamauchi, Kenji| Tanaka, Takehiro| Okada, Hiroyuki| |
| キーワード | 18F-fluorodeoxyglucose-positron emission tomography mesenchymal tumor gastric neoplasms gastrointestinal stromal tumor schwannoma |
| 発行日 | 2020-05-01 |
| 出版物タイトル | Journal of Clinical Medicine |
| 巻 | 9巻 |
| 号 | 5号 |
| 出版者 | MDPI |
| 開始ページ | 1301 |
| ISSN | 2077-0383 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2020 by the authors. |
| 論文のバージョン | publisher |
| PubMed ID | 32370028 |
| DOI | 10.3390/jcm9051301 |
| Web of Science KeyUT | 000540223800058 |
| 関連URL | isVersionOf https://doi.org/10.3390/jcm9051301 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Iwamuro, Masaya| Takahashi, Takahide| Ota, Yoko| Tanaka, Takehiro| Asada, Noboru| Yano, Shuya| Uka, Mayu| Nakamura, Rei| Baba, Yuki| Kawano, Seiji| Kawahara, Yoshiro| Okada, Hiroyuki| |
| 発行日 | 2020-04-09 |
| 出版物タイトル | Case Reports in Gastrointestinal Medicine |
| 巻 | 2020巻 |
| 出版者 | Hindawi |
| 開始ページ | 7947540 |
| ISSN | 2090-6528 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2020 Masaya Iwamuro et al. |
| 論文のバージョン | publisher |
| PubMed ID | 32328319 |
| DOI | 10.1155/2020/7947540 |
| Web of Science KeyUT | 000528921300002 |
| 関連URL | isVersionOf https://doi.org/10.1155/2020/7947540 |
| JaLCDOI | 10.18926/AMO/58271 |
|---|---|
| フルテキストURL | 74_2_129.pdf |
| 著者 | Fukuma, Shogo| Shinya, Takayoshi| Soh, Junichi| Fukuhara, Ryuichiro| Ogawa, Nanako| Higaki, Fumiyo| Tanaka, Takehiro| Ichihara, Eiki| Hiraki, Takao| Toyooka, Shinichi| Kanazawa, Susumu| |
| 抄録 | The aim of this study was to explore enhancement patterns of different types of primary lung cancers on 2-phase dynamic computed tomography (CT). This study included 217 primary lung cancer patients (141 adenocarcinomas [ADs], 48 squamous cell carcinomas [SCCs], 20 small cell lung carcinomas [SCLCs], and 8 others) who were examined using a 2-phase dynamic scan. Regions of interest were identified and mean enhancement values were calculated. After excluding the 20 SCLCs because these lesions had different clinical stages from the other cancer types, the mean attenuation values and subtractions between phases were compared between types of non-small cell lung carcinomas (NSCLCs) using the Kruskal–Wallis test. Late phase attenuation and attenuation of the late minus unenhanced phase (LMU) of SCCs were significantly higher than those of ADs (p<0.05). To differentiate SCC and AD in the late phase, a threshold of 80.21 Hounsfield units (HU) gave 52.9% accuracy. In LMU, a threshold of 52.16 HU gave 59.3% accuracy. Dynamic lung CT has the potential to aid in differentiating among NSCLC types. |
| キーワード | differentiation dynamic computed tomography primary lung cancer enhancement pattern |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2020-04 |
| 巻 | 74巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 129 |
| 終了ページ | 135 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2020 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 32341587 |
| Web of Science KeyUT | 000528278500006 |
| NAID | 120006839450 |
| JaLCDOI | 10.18926/AMO/58270 |
|---|---|
| フルテキストURL | 74_2_123.pdf |
| 著者 | Fukuhara, Ryuichiro| Shinya, Takayoshi| Fukuma, Shogo| Ogawa, Nanako| Masaoka, Yoshihisa| Tanaka, Takehiro| Marunaka, Hidenori| Arioka, Tadashi| Hiraki, Takao| Kaji, Mitsumasa| Kanazawa, Susumu| |
| 抄録 | The aim of this study was to evaluate the ability of pretreatment 90-min 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) to predict the extranodular spread of lymph node metastases in oral squamous cell carcinoma. We retrospectively reviewed the cases of 56 patients who underwent pretreatment 18F-FDG PET/CT and surgery with neck dissection. Maximum standardized uptake value, metabolic tumor volume, and total lesion glycolysis were measured for the 56 primary sites and maximum standardized uptake value was measured for 115 lymph node levels. Extranodular spread was present at 9 lymph node levels in 7 patients. Significant differences were found in metabolic tumor volume and total lesion glycolysis of the primary site, and in lymph node maximum standardized uptake value, between patients with and without extranodular spread (p<0.05). Combining primary site total lesion glycolysis and lymph node maximum standardized uptake volume at their respective optimal cutoffs, the sensitivity, specificity, and accuracy for predicting extranodular spread were 89%, 92%, and 92%, respectively. Pretreatment 18F-FDG PET/CT is useful for predicting extranodular spread in patients with oral squamous cell carcinoma. The combined use of primary site total lesion glycolysis and lymph node maximum standardized uptake value showed greater predictive value than either predictor singly. |
| キーワード | 18F-fluorodeoxyglucose positron emission tomography/computed tomography extranodular spread metastasis oral squamous cell carcinoma |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2020-04 |
| 巻 | 74巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 123 |
| 終了ページ | 128 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2020 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 32341586 |
| Web of Science KeyUT | 000528278500005 |
| NAID | 120006839449 |
| フルテキストURL | JCEH59_4_168.pdf |
|---|---|
| 著者 | Matsuo, Toshihiko| Tanaka, Takehiro| |
| キーワード | Intraocular lymphoma central nervous system lymphoma CD5 vitrectomy cell block diffuse large B-cell lymphoma |
| 発行日 | 2019-12-22 |
| 出版物タイトル | Journal of Clinical and Experimental Hematopathology |
| 巻 | 59巻 |
| 号 | 4号 |
| 出版者 | Japanese Society for Lymphoratic Tissue Research |
| 開始ページ | 168 |
| 終了ページ | 174 |
| ISSN | 1346-4280 |
| NCID | AA11556796 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2019 The Japanese Society for Lymphoreticular Tissue Research |
| 論文のバージョン | publisher |
| PubMed ID | 31611509 |
| DOI | 10.3960/jslrt.19019 |
| Web of Science KeyUT | 000503881900003 |
| 関連URL | isVersionOf https://doi.org/10.3960/jslrt.19019 |
| フルテキストURL | SR9_1_4633.pdf |
|---|---|
| 著者 | Morihiro, Toshiaki| Kuroda, Shinji| Kanaya, Nobuhiko| Kakiuchi, Yoshihiko| Kubota, Tetsushi| Aoyama, Katsuyuki| Tanaka, Takehiro| Kikuch, Satoru| Nagasaka, Takeshi| Nishizaki, Masahiko| Kagawa, Shunsuke| Tazawa, Hiroshi| Fujiwara, Toshiyoshi| |
| 発行日 | 2019-3-15 |
| 出版物タイトル | Scientific Reports |
| 巻 | 9巻 |
| 出版者 | Nature Publishing Group |
| 開始ページ | 4633 |
| ISSN | 2045-2322 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2019 |
| 論文のバージョン | publisher |
| PubMed ID | 30874607 |
| DOI | 10.1038/s41598-019-41177-2 |
| Web of Science KeyUT | 000461303000015 |
| 関連URL | isVersionOf https://doi.org/10.1038/s41598-019-41177-2 |
| フルテキストURL | JIMHICR2019.pdf |
|---|---|
| 著者 | Matsuo, Toshihiko| Tanaka, Takehiro| Yamasaki, Osamu| |
| キーワード | BRAF inhibitor BRAF mutation MEK inhibitor PET/CT dabrafenib lacrimal sac malignant melanoma trametinib |
| 備考 | UNSP 2324709619888052| |
| 発行日 | 2019-11-20 |
| 出版物タイトル | Journal of Investigative Medicine High Impact Case Reports |
| 巻 | 7巻 |
| 出版者 | Sage Publications |
| 開始ページ | 1 |
| 終了ページ | 6 |
| ISSN | 2324-7096 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 論文のバージョン | publisher |
| PubMed ID | 31747798 |
| DOI | 10.1177/2324709619888052 |
| Web of Science KeyUT | 000498954100001 |
| 関連URL | isVersionOf https://doi.org/10.1177/2324709619888052 |
| フルテキストURL | ecancermedicalscience2019_933.pdf |
|---|---|
| 著者 | Iwamuro, Masaya| Tanaka, Takehiro| Nishida, Kenji| Kanzaki, Hiromitsu| Kawano, Seiji| Kawahara, Yoshiro| Yoshino, Tadashi| Okada, Hiroyuki| |
| キーワード | follicular gastritis gastric neoplasms gastrointestinal endoscope mucosa-associated lymphoid tissue lymphoma nodular gastritis |
| 発行日 | 2019-06-03 |
| 出版物タイトル | ecancermedicalscience |
| 巻 | 13巻 |
| 出版者 | CANCER INTELLIGENCE |
| 開始ページ | 933 |
| ISSN | 1754-6605 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © the authors |
| 論文のバージョン | publisher |
| PubMed ID | 31281430 |
| DOI | 10.3332/ecancer.2019.933 |
| Web of Science KeyUT | 000472729000001 |
| 関連URL | isVersionOf https://doi.org/10.3332/ecancer.2019.933 |
| フルテキストURL | GRP_8159072.pdf |
|---|---|
| 著者 | Iwamuro, Masaya| Aoyama, Yuki| Suzuki, Seiyuu| Kobayashi, Sayo| Toyokawa, Tatsuya| Moritou, Yuki| Hori, Shinichiro| Matsueda, Kazuhiro| Yoshioka, Masao| Tanaka, Takehiro| Okada, Hiroyuki| |
| 発行日 | 2019-09-08 |
| 出版物タイトル | Gastroenterology Research and Practice |
| 出版者 | Hindawi |
| 開始ページ | 8159072 |
| ISSN | 1687-6121 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | Copyright © 2019 Masaya Iwamuro et al. |
| 論文のバージョン | publisher |
| PubMed ID | 31582972 |
| DOI | 10.1155/2019/8159072 |
| Web of Science KeyUT | 000487588000001 |
| 関連URL | isVersionOf https://doi.org/10.1016/bs.aiip.2019.01.001 |
| JaLCDOI | 10.18926/AMO/57377 |
|---|---|
| フルテキストURL | 73_5_457.pdf |
| 著者 | Iwamuro, Masaya| Takahara, Masahiro| Yamazaki, Tatsuhiro| Tanaka, Takehiro| Kondo, Yoshitaka| Hiraoka, Sakiko| Okada, Hiroyuki| |
| 抄録 | A 60-year-old Caucasian male was diagnosed with lung adenocarcinoma and multiple metastases to the bone, spleen, and brain. He underwent radiotherapy for the brain and lumbar spine metastases, plus chemotherapy (cisplatin and pemetrexed). The chemotherapy was discontinued due to vomiting and hyponatremia, and nivolumab was then administered. Eight months later, 18F-fluorodeoxyglucose positron emission tomography showed tracer uptake in the colon. Colonoscopy revealed a reddish multinodular polyp in the sigmoid colon. The polyp showed irregular microvessels. No colonic mucosal surface structures were observed. Colonic metastasis of the lung carcinoma was highly suspected; the polyp was therefore surgically removed. The histological analysis revealed granulation tissue and suppurative inflammation without neoplastic changes. We diagnosed the lesion as a granulation polyp. Despite the difficulty in diagnosing these lesions due to their rarity and similarity to metastatic colon tumors, we suggest that recognizing the endoscopic features of the polyp surface may allow a preoperative diagnosis. |
| キーワード | colonoscopy colonic neoplasms granulation polyp |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2019-10 |
| 巻 | 73巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 457 |
| 終了ページ | 461 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2019 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 31649373 |
| Web of Science KeyUT | 000491886600012 |
| 著者 | Shinya, Takayoshi| Masaoka, Yoshihisa| Sando, Motohiro| Tanabe, Shin| Okamoto, Soichiro| Ihara, Hiroki| Tanaka, Takehiro| Otani, Shinji| Hiraki, Takao| Kanazawa, Susumu| |
|---|---|
| キーワード | Solitary fibrous tumor (SFT) Intrapulmonary Computed tomography (CT) |
| 発行日 | 2019-06 |
| 出版物タイトル | Radiology Case Reports |
| 巻 | 14巻 |
| 号 | 6号 |
| 出版者 | Elsevier |
| 開始ページ | 755 |
| 終了ページ | 758 |
| ISSN | 1930-0433 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2019 The Authors. |
| 論文のバージョン | publisher |
| PubMed ID | 30992735 |
| DOI | 10.1016/j.radcr.2019.03.023 |
| 関連URL | isVersionof https://doi.org/10.1016/j.radcr.2019.03.023 |
| フルテキストURL | DLD51_1_168.pdf |
|---|---|
| 著者 | Iwamuro, Masaya| Urata, Haruo| Tanaka, Takehiro| Okada, Hiroyuki| |
| 発行日 | 2019-01-31 |
| 出版物タイトル | Digestive and Liver Disease |
| 巻 | 51巻 |
| 号 | 1号 |
| 出版者 | Elsevier |
| 開始ページ | 168 |
| ISSN | 15908658 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2018 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved. |
| 論文のバージョン | author |
| PubMed ID | 30145054 |
| DOI | 10.1016/j.dld.2018.07.031 |
| Web of Science KeyUT | 000454119300026 |
| 関連URL | isVersionOf https://doi.org/10.1016/j.dld.2018.07.031 |
| フルテキストURL | blood_119_1_285.pdf |
|---|---|
| 著者 | Nishimori, Hisakazu| Maeda, Yoshinobu| Teshima, Takanori| Sugiyama, Haruko| Kobayashi, Koichiro| Yamasuji, Yoshiko| Kadohisa, Sachiyo| Uryu, Hidetaka| Takeuchi, Kengo| Tanaka, Takehiro| Yoshino, Tadashi| Iwakura, Yoichiro| Tanimoto, Mitsune| |
| 備考 | This research was originally published in Blood. 2012. © the American Society of Hematology.| |
| 発行日 | 2012-01-05 |
| 出版物タイトル | Blood |
| 巻 | 119巻 |
| 号 | 1号 |
| 開始ページ | 285 |
| 終了ページ | 295 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja |
| 論文のバージョン | publisher |
| PubMed ID | 22077062 |
| DOI | 10.1182/blood-2011-01-332478 |
| Web of Science KeyUT | 000299012400035 |
| 関連URL | https://doi.org/10.1182/blood-2011-01-332478 |
| フルテキストURL | K0005304 other1.pdf |
|---|---|
| 著者 | Igawa, Takuro| Sato, Yasuharu| Takata, Katsuyoshi| Iwaki, Noriko| Tanaka, Takehiro| Asano, Naoko| Maeda, Yoshinobu| Orita, Yorihisa| Nakamura, Naoya| Nakamura, Shigeo| Yoshino, Tadashi| |
| キーワード | Cyclin D2 CD5 Diffuse large B-cell lymphoma |
| 備考 | 学位審査副論文| |
| 発行日 | 2013-05-15 |
| 出版物タイトル | Diagnostic Pathology |
| 巻 | 8巻 |
| 出版者 | BioMed Central |
| 開始ページ | 81 |
| ISSN | 1746-1596 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja |
| 論文のバージョン | publisher |
| PubMed ID | 23675804 |
| DOI | 10.1186/1746-1596-8-81 |
| Web of Science KeyUT | 000319266300002 |
| 関連URL | https://doi.org/10.1186/1746-1596-8-81 http://ousar.lib.okayama-u.ac.jp/54287 |
| JaLCDOI | 10.18926/AMO/54977 |
|---|---|
| フルテキストURL | 71_2_97.pdf |
| 著者 | Iwamuro, Masaya| Kondo, Eisei| Tanaka, Takehiro| Hagiya, Hideharu| Kawano, Seiji| Kawahara, Yoshiro| Otsuka, Fumio| Okada, Hiroyuki| |
| 抄録 | We retrospectively analyzed the cases of 14 patients (9 women, 5 men, mean age: 51.6 years) with cytomegalovirus (CMV) involvement in the esophagus, stomach, and/or duodenum diagnosed at a single center, to determine their endoscopic features and clinical backgrounds. Thirteen patients (92.9%) had hematologic disease; the other had rheumatoid arthritis. Of the former, 12 patients underwent allogeneic hematopoietic stem cell transplantation, and 9 of these patients had graft-versus-host disease (GVHD) before undergoing esophagogastroduodenoscopy (EGD). All 14 patients had been taking one or more immunosuppressive agents including cyclosporine (n=10), corticosteroids (n=9), mycophenolic acid (n=6), tacrolimus (n=3), and methotrexate (n=1). Tests for CMV antigenemia were positive in 11 patients (78.6%). EGD examinations revealed esophageal (n=3), gastric (n=9), and duodenal involvement (n=6). Macroscopically, esophageal lesions by CMV infection presented as redness (n=1), erosions (n=1), and ulcers (n=1). Gastric lesions manifested as redness (n=7), erosions (n=3), exfoliated mucosa (n=2), and verrucous erosions (n=1). Mucosal appearances in the duodenum varied: redness (n=2), ulcers (n=2), multiple erosions (n=2), single erosion (n=1), edema (n=1). CMV was detected even in the intact duodenal mucosa (n=1). In conclusion, physicians must recall the relevance of CMV infection when any mucosal alterations exist in the upper gastrointestinal tract of immunosuppressed patients. |
| キーワード | cytomegalovirus duodenum esophagogastroduodenoscopy esophagus stomach |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2017-04 |
| 巻 | 71巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 97 |
| 終了ページ | 104 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2017 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 28420890 |
| 著者 | Iwamuro, Masaya| Urata, Haruo| Tanaka, Takehiro| Ando, Akemi| Nada, Takahiro| Kimura, Kosuke| Yamauchi, Kenji| Kusumoto, Chiaki| Otsuka, Fumio| Okada, Hiroyuki| |
|---|---|
| 発行日 | 2017-02 |
| 出版物タイトル | Acta Medica Okayama |
| 巻 | 71巻 |
| 号 | 1号 |
| 資料タイプ | 学術雑誌論文 |
| JaLCDOI | 10.18926/AMO/54828 |
| JaLCDOI | 10.18926/AMO/54817 |
|---|---|
| フルテキストURL | 70_6_511.pdf |
| 著者 | Gobara, Hideo| Hiraki, Takao| Iguchi, Toshihiro| Fujiwara, Hiroyasu| Nagasaka, Takeshi| Kishimoto, Hiroyuki| Tanaka, Takehiro| Kanazawa, Susumu| |
| 抄録 | An 87-year-old Japanese man underwent percutaneous cryoablation (PCA) therapy for his renal cell tumor. We displaced the colon from the tumor using hydrodissection. Computed tomography (CT) immediately after PCA was indicative of iceball extension to the colon wall, and a discontinuous enhancement of the colon wall was observed. We therefore performed an emergency surgery. On laparotomy, we observed a dark-purple area on the affected area of the colon, and the resected specimen showed focal, deep ulceration on the mucosal surface. Photomicrography revealed mucosal necrosis, submucosal hemorrhage, and necrotic foci in the muscularis propria, corresponding to the discontinuous colon wall enhancement on CT and the deep ulceration and dark-purple area on laparotomy. He recovered from surgery and was discharged without any complications. |
| キーワード | bowel injury complication cryoablation renal cell carcinoma thermal ablation |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2016-12 |
| 巻 | 70巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 511 |
| 終了ページ | 514 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2016 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 28003679 |
| JaLCDOI | 10.18926/AMO/54815 |
|---|---|
| フルテキストURL | 70_6_503.pdf |
| 著者 | Kanazawa, Yui| Yamashita, Yuka| Fujiwara, Mitsuhiro| Muraoka, Michiko| Washio, Kana| Kanamitsu, Kiichiro| Ishida, Hisashi| Nakano, Takae| Yamada, Miho| Horibe, Keizo| Tanaka, Takehiro| Yoshino, Tadashi| Shimada, Akira| |
| 抄録 | Childhood anaplastic large cell lymphoma (ALCL) accounts for approx. 10–30 of cases of non-Hodgkin lymphoma, and the ALCL99 study reported 60–75 disease-free survival; however, a relatively high relapse rate was observed (25–30 ). We report 2 patients with Stage III ALCL who relapsed 6–18 months after the end of ALCL99 chemotherapy. A retrospective molecular analysis identified the nucleophosmin (NPM)-anaplastic lymphoma kinase (ALK) fusion gene in the first diagnostic bone marrow samples taken from both patients. However, antibodies against the ALK protein appeared to be relatively low in the serum of both patients (×100 and ×750). An increase in chemotherapy intensity may be beneficial if Stage III ALCL patients are shown to be NPM-ALK chimera-positive in the first diagnostic bone marrow sample. |
| キーワード | ALCL NPM-ALK fusion lymphoma |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2016-12 |
| 巻 | 70巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 503 |
| 終了ページ | 506 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2016 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 28003677 |
| 著者 | 後藤田 達洋| 川野 誠司| 河野 吉泰| 三浦 公| 神崎 洋光| 岩室 雅也| 河原 祥朗| 田中 健大| 吉野 正| 白川 靖博| 田端 雅弘| 谷本 光音| 岡田 裕之| |
|---|---|
| 発行日 | 2016-12-01 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 128巻 |
| 号 | 3号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 岩室 雅也| 岡田 裕之| 原田 馨太| 神崎 洋光| 堀 圭介| 喜多 雅英| 川野 誠司| 河原 祥朗| 田中 健大| 山本 和秀| |
|---|---|
| 発行日 | 2016-12-01 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 128巻 |
| 号 | 3号 |
| 資料タイプ | 学術雑誌論文 |