ID | 50632 |
フルテキストURL | |
著者 |
Motose, Hiroyasu
Division of Biological Sciences; Graduate School of Natural Science and Technology; Okayama University
ORCID
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Takatani, Shogo
Division of Biological Sciences; Graduate School of Natural Science and Technology; Okayama University
Ikeda, Tatsuya
Division of Biological Sciences; Graduate School of Natural Science and Technology; Okayama University
Takahashi, Taku
Division of Biological Sciences; Graduate School of Natural Science and Technology; Okayama University
ORCID
Kaken ID
researchmap
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抄録 | NIMA-related kinase 6 (NEK6) regulates cellular expansion and morphogenesis through microtubule organizaiton in Arabidopsis thaliana. Loss-of-function mutations in NEK6 (nek6/ibo1) cause ectopic outgrowth and microtubule disorganization in epidermal cells. We recently found that NEK6 forms homodimers and heterodimers with NEK4 and NEK5 to destabilize cortical microtubules possibly by direct binding to microtubules and the β-tubulin phosphorylation. Here, we identified a new allele of NEK6 and further analyzed the morphological phenotypes of nek6/ibo1 mutants, along with alleles of nek4 and nek5 mutants. Phenotypic analysis demonstrated that NEK6 is required for the directional growth of roots and hypocotyls, petiole elongation, cell file formation, and trichome morphogenesis. In addition, nek4, nek5, and nek6/ibo1 mutants were hypersensitive to microtubule inhibitors such as propyzamide and taxol. These results suggest that plant NEKs function in directional cell growth and organ development through the regulation of microtubule organization.
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キーワード | Arabidopsis
NIMA-related kinase
directional growth
epidermis
microtubule
tubulin
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発行日 | 2012-12
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出版物タイトル |
Plant Signaling & Behavior
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巻 | 7巻
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号 | 12号
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開始ページ | 1552
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終了ページ | 1555
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ISSN | 1559-2316
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資料タイプ |
学術雑誌論文
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言語 |
英語
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著作権者 | © 2012 Landes Bioscience
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論文のバージョン | author
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査読 |
有り
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DOI | |
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