IMPACT OF MACULAR INTRARETINAL HEMORRHAGE AND MACULAR HOLE ON THE VISUAL PROGNOSIS OF SUBMACULAR HEMORRHAGE DUE TO RETINAL ARTERIAL MACROANEURYSM RUPTURE

Doi, Shinichiro; Kimura, Shuhei; Saito, Shoko; Inoue, Makoto; Sakurai, Toshiya; Kobori, Akira; Hisatomi, Toshio; Imai, Hisanori; Kuriyama, Shoji; Takasu, Ippei; Hosokawa, Mio Morizane; Shiode, Yusuke; Matoba, Ryo; Suzuki, Etsuji; Morizane, Yuki

doi:10.1097/iae.0000000000003725

Permalink : https://ousar.lib.okayama-u.ac.jp/65516

ID	65516
フルテキストURL	fulltext20230619-11.pdf 363 KB table20230619-11.pdf 269 KB fig1_20230619-11.pdf 53.2 KB fig2_20230619-11.pdf 116 KB fig3_20230619-11.pdf 86.6 KB fig4_20230619-11.pdf 125 KB fig5_20230619-11.pdf 81.9 KB fig6_20230619-11.pdf 91.5 KB suppl1_20230619-11.pdf 161 KB suppl2_20230619-11.pdf 182 KB
著者	Doi, Shinichiro Department of Ophthalmology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University Kimura, Shuhei Department of Ophthalmology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University ORCID Kaken ID Saito, Shoko Kyorin Eye Center, Kyorin University School of Medicine Inoue, Makoto Kyorin Eye Center, Kyorin University School of Medicine Sakurai, Toshiya Department of Ophthalmology, Tane Memorial Eye Hospital Kobori, Akira Department of Ophthalmology, Fukui Red Cross Hospital Hisatomi, Toshio Department of Ophthalmology, Chikushi Hospital, Fukuoka University Imai, Hisanori Division of Ophthalmology, Department of Surgery, Kobe University Graduate School of Medicine Kuriyama, Shoji Otowa Eye Center Takasu, Ippei Takasu Eye Clinic Hosokawa, Mio Morizane Department of Ophthalmology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University Shiode, Yusuke Department of Ophthalmology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University Kaken ID Matoba, Ryo Department of Ophthalmology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University Suzuki, Etsuji Department of Epidemiology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University Kaken ID publons researchmap Morizane, Yuki Department of Ophthalmology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
抄録	Purpose: To compare the effects of macular intraretinal hemorrhage (IRH) and macular hole (MH) on best-corrected visual acuity (BCVA) after displacement of submacular hemorrhage (SMH) due to retinal arterial macroaneurysm (RAM) rupture. Methods: This multicenter retrospective study included 48 eyes with SMH due to RAM rupture. Cases underwent vitrectomy to displace SMH and were followed up for 6 months. We classified cases according to the presence of IRH and MH and compared the postoperative BCVA among the groups. Results: We classified the eyes into IRH(+)MH(+) group (10 eyes), IRH(+)MH(−) group (23 eyes), and IRH(−)MH(−) group (15 eyes). The postoperative BCVA was significantly worse in the IRH(+)MH(+) and IRH(+)MH(−) groups than in the IRH(−)MH(−) group (0.91 ± 0.41 in logarithm of the minimal angle of resolution units, Snellen equivalent 20/163, 0.87 ± 0.45, 20/148, and 0.18 ± 0.21, 20/30, respectively; P < 0.001). The postoperative central retinal thickness was significantly lower in the IRH(+) group (IRH(+)MH(+) and IRH(+)MH(−) groups combined) than in the IRH(−) group (IRH(−)MH(−) group) (121.4 ± 70.1 µm and 174.3 ± 32.9 µm, respectively, P = 0.008). The postoperative external limiting membrane and ellipsoid zone continuities were significantly discontinuous in the IRH(+) group (P < 0.001, P = 0.001, respectively). The multiple linear regression analysis showed that both IRH(+)MH(+) and IRH(+)MH(−) were associated with the postoperative BCVA (regression coefficient, 0.799 and 0.711, respectively; P < 0.001 for both). Conclusion: Both IRH and MH were poor prognostic indicators in cases with SMH due to RAM rupture.
キーワード	macular intraretinal hemorrhage macular hole submacular hemorrhage retinal arterial macroaneurysm fluffy sign tissue plasminogen activator
備考	This is a non-final version of an article published in final form in (Doi, Shinichiro MD, PhD; Kimura, Shuhei MD, PhD; Saito, Shoko MD†; Inoue, Makoto MD, PhD†; Sakurai, Toshiya MD, PhD‡; Kobori, Akira MD§; Hisatomi, Toshio MD, PhD¶; Imai, Hisanori MD, PhD*; Kuriyama, Shoji MD, PhD††; Takasu, Ippei MD‡‡; Hosokawa, Mio Morizane MD, PhD; Shiode, Yusuke MD, PhD; Matoba, Ryo MD, PhD; Suzuki, Etsuji MD, PhD§§; Morizane, Yuki MD, PhD*. IMPACT OF MACULAR INTRARETINAL HEMORRHAGE AND MACULAR HOLE ON THE VISUAL PROGNOSIS OF SUBMACULAR HEMORRHAGE DUE TO RETINAL ARTERIAL MACROANEURYSM RUPTURE. Retina 43(4):p 585-593, April 2023. \| DOI: 10.1097/IAE.0000000000003725).
発行日	2023-04
出版物タイトル	Retina
巻	43巻
号	4号
出版者	Ovid Technologies (Wolters Kluwer Health)
開始ページ	585
終了ページ	593
ISSN	0275-004X
NCID	AA10639923
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2023, Wolters Kluwer Health
論文のバージョン	author
PubMed ID	36735920
DOI	10.1097/iae.0000000000003725
Web of Science KeyUT	000982414100014
関連URL	isVersionOf https://doi.org/10.1097/iae.0000000000003725
Citation	Doi, Shinichiro MD, PhD; Kimura, Shuhei MD, PhD; Saito, Shoko MD†; Inoue, Makoto MD, PhD†; Sakurai, Toshiya MD, PhD‡; Kobori, Akira MD§; Hisatomi, Toshio MD, PhD¶; Imai, Hisanori MD, PhD*; Kuriyama, Shoji MD, PhD††; Takasu, Ippei MD‡‡; Hosokawa, Mio Morizane MD, PhD; Shiode, Yusuke MD, PhD; Matoba, Ryo MD, PhD; Suzuki, Etsuji MD, PhD§§; Morizane, Yuki MD, PhD*. IMPACT OF MACULAR INTRARETINAL HEMORRHAGE AND MACULAR HOLE ON THE VISUAL PROGNOSIS OF SUBMACULAR HEMORRHAGE DUE TO RETINAL ARTERIAL MACROANEURYSM RUPTURE. Retina 43(4):p 585-593, April 2023. \| DOI: 10.1097/IAE.0000000000003725