岸本浩行

Predictive marker for response to trifluridine/tipiracil plus bevacizumab in metastatic colorectal cancer patients

フルテキストURL	fulltext.pdf
著者	Takahashi, Toshiaki\| Shigeyasu, Kunitoshi\| Kondo, Yoshitaka\| Takeda, Sho\| Umeda, Hibiki\| Moriwake, Kazuya\| Kayano, Masashi\| Sakurai, Yuya\| Nakamura, Shunsuke\| Takahashi, Masafumi\| Nitta, Kaori\| Yoshida, Kazuhiro\| Matsumi, Yuki\| Michiue, Hiroyuki\| Yamamoto, Hideki\| Kishimoto, Hiroyuki\| Teraishi, Fuminori\| Shoji, Ryohei\| Kanaya, Nobuhiko\| Kashima, Hajime\| Kakiuchi, Yoshihiko\| Kuroda, Shinji\| Kagawa, Shunsuke\| Fujiwara, Toshiyoshi\|
キーワード	ADAR1 Colorectal cancer Biomarker Trifluridine/tipiracil
備考	The version of record of this article, first published in BMC Cancer, is available online at Publisher’s website: http://dx.doi.org/10.1186/s12885-024-13370-8\|
発行日	2025-01-02
出版物タイトル	BMC Cancer
巻	25巻
号	1号
出版者	BMC
開始ページ	1
ISSN	1471-2407
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2024.
論文のバージョン	publisher
PubMed ID	39748254
DOI	10.1186/s12885-024-13370-8
Web of Science KeyUT	001389189700001
関連URL	isVersionOf https://doi.org/10.1186/s12885-024-13370-8

ADAR1 is a promising risk stratification biomarker of remnant liver recurrence after hepatic metastasectomy for colorectal cancer

フルテキストURL	fulltext.pdf
著者	Hata, Nanako\| Shigeyasu, Kunitoshi\| Umeda, Yuzo\| Yano, Shuya\| Takeda, Sho\| Yoshida, Kazuhiro\| Fuji, Tomokazu\| Yoshida, Ryuichi\| Yasui, Kazuya\| Umeda, Hibiki\| Takahashi, Toshiaki\| Kondo, Yoshitaka\| Kishimoto, Hiroyuki\| Mori, Yoshiko\| Teraishi, Fuminori\| Yamamoto, Hideki\| Michiue, Hiroyuki\| Nakamura, Keiichiro\| Tazawa, Hiroshi\| Fujiwara, Toshiyoshi\|
備考	The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-023-29397-z\|
発行日	2023-02-06
出版物タイトル	Scientific Reports
巻	13巻
号	1号
出版者	Nature Portfolio
開始ページ	2078
ISSN	2045-2322
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2023
論文のバージョン	publisher
PubMed ID	36747029
DOI	10.1038/s41598-023-29397-z
Web of Science KeyUT	000989985700018
関連URL	isVersionOf https://doi.org/10.1038/s41598-023-29397-z

RNA editing facilitates the enhanced production of neoantigens during the simultaneous administration of oxaliplatin and radiotherapy in colorectal cancer

フルテキストURL	fulltext.pdf
著者	Komatsu, Yasuhiro\| Shigeyasu, Kunitoshi\| Yano, Shuya\| Takeda, Sho\| Takahashi, Kazutaka\| Hata, Nanako\| Umeda, Hibiki\| Yoshida, Kazuhiro\| Mori, Yoshiko\| Yasui, Kazuya\| Yoshida, Ryuichi\| Kondo, Yoshitaka\| Kishimoto, Hiroyuki\| Teraishi, Fuminori\| Umeda, Yuzo\| Kagawa, Shunsuke\| Michiue, Hiroyuki\| Tazawa, Hiroshi\| Goel, Ajay\| Fujiwara, Toshiyoshi\|
発行日	2022-08-08
出版物タイトル	Scientific Reports
巻	12巻
号	1号
出版者	Nature Portfolio
開始ページ	13540
ISSN	2045-2322
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© TheAuthor(s)2022
論文のバージョン	publisher
PubMed ID	35941214
DOI	10.1038/s41598-022-17773-0
Web of Science KeyUT	000837764800013
関連URL	isVersionOf https://doi.org/10.1038/s41598-022-17773-0

Concordance of acquired mutations between metastatic lesions and liquid biopsy in metastatic colorectal cancer

フルテキストURL	fulltext.pdf
著者	Taniguchi, Fumitaka\| Nyuya, Akihiro\| Toshima, Toshiaki\| Yasui, Kazuya\| Mori, Yoshiko\| Okawaki, Makoto\| Kishimoto, Hiroyuki\| Umeda, Yuzo\| Fujiwara, Toshiyoshi\| Tanioka, Hiroaki\| Yamaguchi, Yoshiyuki\| Goel, Ajay\| Nagasaka, Takeshi\|
キーワード	Acquired mutations BRAF colorectal cancer liquid biopsy PCR-rSSO RAS
出版物タイトル	Future Science OA
出版者	Future Science Ltd.
開始ページ	FSO757
ISSN	2056-5623
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2021 Authors
論文のバージョン	publisher
DOI	10.2144/fsoa-2021-0059
Web of Science KeyUT	000715287900001
関連URL	isVersionOf https://doi.org/10.2144/fsoa-2021-0059

Real-Time Fluorescence Image-Guided Oncolytic Virotherapy for Precise Cancer Treatment

フルテキストURL	fulltext.pdf
著者	Yano, Shuya\| Tazawa, Hiroshi\| Kishimoto, Hiroyuki\| Kagawa, Shunsuke\| Fujiwara, Toshiyoshi\| Hoffman, Robert M.\|
キーワード	cancer cell cycle fluorescent proteins FUCCI imaging adenovirus oncolytic virotherapy cancer stem cell mouse model orthotopic
発行日	2021-01-17
出版物タイトル	International Journal of Molecular Sciences
巻	22巻
号	2号
出版者	MDPI
開始ページ	879
ISSN	1422-0067
NCID	AA12038549
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2021 by the authors.
論文のバージョン	publisher
PubMed ID	33477279
DOI	10.3390/ijms22020879
Web of Science KeyUT	000611296000001
関連URL	isVersionOf https://doi.org/10.3390/ijms22020879

Visualization of epithelial-mesenchymal transition in an inflammatory microenvironment-colorectal cancer network

著者	Ieda, Takeshi\| Tazawa, Hiroshi\| Okabayashi, Hiroki\| Yano, Shuya\| Shigeyasu, Kunitoshi\| Kuroda, Shinji\| Ohara, Toshiaki\| Noma, Kazuhiro\| Kishimoto, Hiroyuki\| Nishizaki, Masahiko\| Kagawa, Shunsuke\| Shirakawa, Yasuhiro\| Saitou, Takashi\| Imamura, Takeshi\| Fujiwara, Toshiyoshi\|
発行日	2019-11-8
出版物タイトル	Scientific Reports
巻	9巻
出版者	Nature Publishing Group
開始ページ	16378
ISSN	2045-2322
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2019
論文のバージョン	publisher
PubMed ID	31705021
DOI	10.1038/s41598-019-52816-z
Web of Science KeyUT	000495372900001
関連URL	isVersionOf https://doi.org/10.1038/s41598-019-52816-z

Acute Bowel Injury due to Cryoablation for Renal Cell Carcinoma: Correlated Radiologic and Pathologic Findings

JaLCDOI	10.18926/AMO/54817
フルテキストURL	70_6_511.pdf
著者	Gobara, Hideo\| Hiraki, Takao\| Iguchi, Toshihiro\| Fujiwara, Hiroyasu\| Nagasaka, Takeshi\| Kishimoto, Hiroyuki\| Tanaka, Takehiro\| Kanazawa, Susumu\|
抄録	An 87-year-old Japanese man underwent percutaneous cryoablation (PCA) therapy for his renal cell tumor. We displaced the colon from the tumor using hydrodissection. Computed tomography (CT) immediately after PCA was indicative of iceball extension to the colon wall, and a discontinuous enhancement of the colon wall was observed. We therefore performed an emergency surgery. On laparotomy, we observed a dark-purple area on the affected area of the colon, and the resected specimen showed focal, deep ulceration on the mucosal surface. Photomicrography revealed mucosal necrosis, submucosal hemorrhage, and necrotic foci in the muscularis propria, corresponding to the discontinuous colon wall enhancement on CT and the deep ulceration and dark-purple area on laparotomy. He recovered from surgery and was discharged without any complications.
キーワード	bowel injury complication cryoablation renal cell carcinoma thermal ablation
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2016-12
巻	70巻
号	6号
出版者	Okayama University Medical School
開始ページ	511
終了ページ	514
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2016 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	28003679

A Case-matched Comparative Study of Laparoscopic and Open Total Proctocolectomy for Ulcerative Colitis

JaLCDOI	10.18926/AMO/53672
フルテキストURL	69_5_267.pdf
著者	Inada, Ryo\| Nagasaka, Takeshi\| Kondo, Yoshitaka\| Watanabe, Ayako\| Toshima, Toshiaki\| Kubota, Nobuhito\| Kikuchi, Satoru\| Ishida, Michihiro\| Kuroda, Shinji\| Mori, Yoshiko\| Kishimoto, Hiroyuki\| Fujiwara, Toshiyoshi\|
抄録	The aim of this single-institution, retrospective, observational case-control study was to evaluate the safety and feasibility of laparoscopic proctocolectomy (PC) for ulcerative colitis (UC), by comparing it with a case-control series of open PC. Twenty UC patients who underwent laparoscopic PC were retrospectively compared with the open PC group of 12 patients matched for age, sex, and urgency of the operation. In the laparoscopic PC group, the operative time was significantly longer, but the amount of blood loss was significantly smaller. The open PC patients underwent an intraoperative blood transfusion significantly more often, and the serum C-reactive protein level on the first postoperative day was significantly higher in the open PC group. In the laparoscopic PC group, the rate of severe postoperative morbidities, grades 3 and 4 on the Clavien-Dindo classification, was significantly lower, and the median length of hospital stay was significantly shorter. Laparoscopic PC for patients with UC showed superior perioperative outcomes to open PC, except for longer operative time.
キーワード	laparoscopic surgery total proctocolectomy open proctocolectomy ulcerative colitis case-matched study
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2015-10
巻	69巻
号	5号
出版者	Okayama University Medical School
開始ページ	267
終了ページ	273
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2015 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	26490023
Web of Science KeyUT	000365519600002

超高齢者（95歳）の進行盲腸癌に対して腹腔鏡下回盲部切除を施行した1例

タイトル（別表記）	Successful laparoscopic resection of a cecal tumor in a 95-year-old man
フルテキストURL	127_117.pdf
著者	渡邉彩子\| 稲田涼\| 永坂岳司\| 八木朝彦\| 松本聖\| 戸嶋俊明\| 菊池覚次\| 黒田新士\| 近藤喜太\| 母里淑子\| 岸本浩行\| 藤原俊義\|
抄録	We report a successful laparoscopic resection of a cecal tumor in a 95-year-old Japanese man. The patient visited an initial hospital with a complaint of constipation in March 2014. Computed tomography scan and colonoscopy showed a stenotic ileocecal cancer with pericolic lymph node metastases, and he was referred to our department for management. Since his general condition was maintained, we performed a laparoscopic ileocecal resection with regional lymph node dissection for the patient. The operation achieved curative resection, and the tumor was diagnosed as a moderately differentiated adenocarcinoma and graded as pStage IIIa (pT3, pN0, pM0) according to the Japanese Classification of Colorectal Carcinoma, eighth edition. He was discharged on the 11th postoperative day without perioperative complications. Several large-scale randomized controlled trials （RCTs） revealed that laparoscopic surgeries for colorectal cancers have some advantages compared to open surgeries, including superior short-term outcomes and comparable long-term outcomes. Unfortunately, since these RCTs did not include enough elderly patients, the safety and feasibility of laparoscopic surgery for extremely elderly patients are still unknown. With respect to less-invasive procedures, these advantages of laparoscopic surgery are also thought to be the advantages for elderly colorectal cancer patients.
キーワード	超高齢者（extremely elderly patient）大腸癌（colorectal cancer）腹腔鏡手術（laparoscopic surgery）
出版物タイトル	岡山医学会雑誌
発行日	2015-08-03
巻	127巻
号	2号
開始ページ	117
終了ページ	121
ISSN	0030-1558
関連URL	isVersionOf https://doi.org/10.4044/joma.127.117
言語	日本語
著作権者	Copyright (c) 2015 岡山医学会
論文のバージョン	publisher
DOI	10.4044/joma.127.117
NAID	130005096253

Aggressive Multimodality Treatment for Advanced Rectal Cancer

JaLCDOI	10.18926/AMO/53340
フルテキストURL	69_2_113.pdf
著者	Inada, Ryo\| Nagasaka, Takeshi\| Toshima, Toshiaki\| Mori, Yoshiko\| Kondo, Yoshitaka\| Kishimoto, Hiroyuki\| Hiraki, Takao\| Oshiro, Taihei\| Kanemitsu, Yukihide\| Fujiwara, Toshiyoshi\|
抄録	A case of advanced rectal cancer treated by aggressive local and systemic treatment who has survived more than 7 years from initial recurrence is presented. A 55-year-old woman was diagnosed with advanced lower rectal cancer and underwent a low anterior resection with complete removal of all regional lymph nodes and total mesorectal excision. The tumor was diagnosed as a moderately differentiated adenocarcinoma, pStage IIIB (T3, N2a, M0). Twenty-six months after the initial surgery, local recurrence in the pelvis was detected by computed tomography, and total pelvic exenteration with distal sacrectomy (TPES) was performed after systemic chemotherapy with a molecular-targeted drug. Six months after the TPES, multiple lung metastases were detected. Consequently, the patient underwent radiofrequency ablation (RFA) and chemotherapy. The disease has since been controlled for 38 months. As volume control is essential for cancer treatment, it may be important to combine appropriate local therapy with systemic therapy to metastatic or recurrent sites in order to achieve much longer disease control.
キーワード	colorectal cancer recurrence total pelvic exenteration radiofrequency ablation systemic chemotherapy
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2015-04
巻	69巻
号	2号
出版者	Okayama University Medical School
開始ページ	113
終了ページ	118
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2015 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	25899633
Web of Science KeyUT	000353181700006

Biological Ablation of Sentinel Lymph Node Metastasis in Submucosally Invaded Early Gastrointestinal Cancer

著者	Kikuchi, Satoru\| Kishimoto, Hiroyuki\| Tazawa, Hiroshi\| Hashimoto, Yuuri\| Kuroda, Shinji\| Nishizaki, Masahiko\| Nagasaka, Takeshi\| Shirakawa, Yasuhiro\| Kagawa, Shunsuke\| Urata, Yasuo\| Robert M Hoffman\| Fujiwara, Toshiyoshi\|
発行日	2014-12-19
出版物タイトル	Molecular Therapy
資料タイプ	学術雑誌論文

Fluorescence virus-guided capturing system of human colorectal circulating tumour cells for non-invasive companion diagnostics

著者	Shigeyasu, Kunitoshi\| Tazawa, Hiroshi\| Hashimoto, Yuuri\| Mori, Yoshiko\| Nishizaki, Masahiko\| Kishimoto, Hiroyuki\| Nagasaka, Takeshi\| Kuroda, Shinji\| Urata, Yasuo\| Goel, Ajay\| Kagawa, Shunsuke\| Fujiwara, Toshiyoshi\|
発行日	2014-05-28
出版物タイトル	Gut
資料タイプ	学術雑誌論文

A Genetically Engineered Oncolytic Adenovirus Decoys and Lethally Traps Quiescent Cancer Stem-like Cells in S/G(2)/M Phases

著者	Yano, Shuya\| Tazawa, Hiroshi\| Hashimoto, Yuuri\| Shirakawa, Yasuhiro\| Kuroda, Shinji\| Nishizaki, Masahiko\| Kishimoto, Hiroyuki\| Uno, Futoshi\| Nagasaka, Takeshi\| Urata, Yasuo\| Kagawa, Shunsuke\| Hoffman, Robert M.\| Fujiwara, Toshiyoshi\|
発行日	2013-12-01
出版物タイトル	Clinical Cancer Research
巻	19巻
号	23号
資料タイプ	学術雑誌論文

Mechanism of resistance to trastuzumab and molecular sensitization via ADCC activation by exogenous expression of HER2-extracellular domain in human cancer cells

著者	Yoshida, Ryosuke\| Tazawa, Hiroshi\| Hashimoto, Yuuri\| Yano, Shuya\| Onishi, Teppei\| Sasaki, Tsuyoshi\| Shirakawa, Yasuhiro\| Kishimoto, Hiroyuki\| Uno, Futoshi\| Nishizaki, Masahiko\| Kagawa, Shunsuke\| Fujiwara, Toshiyoshi\|
発行日	2012-11
出版物タイトル	Cancer Immunology, Immunotherapy
巻	61巻
号	11号
資料タイプ	学術雑誌論文

岸本 浩行