ID | 30377 |
JaLCDOI | |
フルテキストURL | |
著者 |
Furuno, Katsushi
Okayama University
Okazaki, Masatoshi
Okayama University
Eto, Kohei
Okayama Univresity
Gomita, Yutaka
Okayama University
|
抄録 | The effects of acute exposure to cigarette smoke and systemic administration of nicotine on intestinal propulsion were investigated in rats. The propulsive activity was measured as migration of charcoal powder in the intestine. This activity was suppressed by acute exposure (10 min) to cigarette smoke and by nicotine (0.5 mg/kg x 2, s.c.) administration. This intestinal suppression was more marked in the rats given nicotine than in those exposed to cigarette smoke, whereas the plasma concentrations of nicotine in both rats were similar. These results suggest that acute exposure to cigarette smoke and nicotine administration delay gastric emptying and/or suppress intestinal propulsion, and that some components other than nicotine contained in cigarette smoke may attenuate the suppression of intestinal propulsion induced by nicotine. |
キーワード | cigarette smoke
nicotine
intestinal propulsion
|
Amo Type | Article
|
出版物タイトル |
Acta Medica Okayama
|
発行日 | 1995-08
|
巻 | 49巻
|
号 | 4号
|
出版者 | Okayama University Medical School
|
開始ページ | 201
|
終了ページ | 204
|
ISSN | 0386-300X
|
NCID | AA00508441
|
資料タイプ |
学術雑誌論文
|
言語 |
英語
|
論文のバージョン | publisher
|
査読 |
有り
|
PubMed ID | |
Web of Science KeyUT |