フルテキストURL fulltext.pdf
著者 Nakamura, Keiichiro| Matsuoka, Hirofumi| Kubo, Kotaro| Shirakawa, Shinsuke| Ida, Naoyuki| Haraga, Junko| Ogawa, Chikako| Okamoto, Kazuhiro| Nagao, Shoji| Masuyama, Hisashi|
キーワード returning to the same workplace gynecologic neoplasms sick leave
発行日 2023-11-23
出版物タイトル Japanese Journal of Clinical Oncology
54巻
3号
出版者 Oxford University Press (OUP)
開始ページ 292
終了ページ 296
ISSN 1465-3621
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s) 2023.
論文のバージョン publisher
PubMed ID 37995280
DOI 10.1093/jjco/hyad159
Web of Science KeyUT 001108594700001
関連URL isVersionOf https://doi.org/10.1093/jjco/hyad159
フルテキストURL fulltext.pdf
著者 Mitoma, Tomohiro| Maki, Jota| Ooba, Hikaru| Ogawa, Chikako| Masuyama, Hisashi| Tabuchi, Takahiro|
キーワード cervical cancer screening social inequality screening hesitation internet survey
発行日 2024-02-13
出版物タイトル International Journal of General Medicine
17巻
出版者 Dove Press
開始ページ 541
終了ページ 551
ISSN 1178-7074
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2024 Mitoma et al.
論文のバージョン publisher
PubMed ID 38371520
DOI 10.2147/IJGM.S453675
Web of Science KeyUT 001162765400001
関連URL isVersionOf https://doi.org/10.2147/IJGM.S453675
JaLCDOI 10.18926/AMO/63406
フルテキストURL 76_2_129.pdf
著者 Kubo, Kotaro| Nakamura, Keiichiro| Okamoto, Kazuhiro| Matsuoka, Hirofumi| Ida, Naoyuki| Haruma, Tomoko| Ogawa, Chikako| Masuyama, Hisashi|
抄録 Cancer patients have increased risk of venous thromboembolism (VTE) that must be assessed before treatment. This study aimed to determine effective VTE biomarkers in gynecologic cancer (GC). We investigated the correlation between D-dimer levels, Khorana risk score (KRS), Glasgow prognostic score (GPS), and VTE in 1499 GC patients (583 cervical cancer (CC), 621 endometrial cancer (EC), and 295 ovarian cancer (OC) patients) treated at our institution between January 2008 and December 2019. χ2 and Mann–Whitney U-tests were used to determine statistical significance. We used receiver operating characteristic-curve analysis to evaluate the discriminatory ability of each parameter. D-dimer levels were significantly correlated with KRS and GPS in patients with GC. VTE was diagnosed in 11 CC (1.9%), 27 EC (4.3%), and 39 OC patients (13.2%). Optimal D-dimer cut-off values for VTE were 3.1, 3.2, and 3.9 μg/ml in CC, EC and OC patients, respectively. D-dimer could significantly predict VTE in all GC patients. Furthermore, D-dimer combined with GPS was more accurate in predicting VTE than other VTE biomarkers in stage IIIC and IVA OC (AUC: 0.846; p<0.001). This study demonstrates that combined D-dimer and GPS are useful in predicting VTE in patients with OC.
キーワード D-dimer gynecologic cancer venous thromboembolism
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2022-04
76巻
2号
出版者 Okayama University Medical School
開始ページ 129
終了ページ 135
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2022 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 35503440
Web of Science KeyUT 000792374900004
JaLCDOI 10.18926/AMO/62816
フルテキストURL 75_6_745.pdf
著者 Hayata, Kei| Mishima, Sakurako| Ohira, Akiko| Tani, Kazumasa| Maki, Jota| Eto, Eriko| Ogawa, Chikako| Masuyama, Hisashi|
抄録 NIPT is non-definitive testing to estimate the possibility that fetuses have trisomy 21, trisomy 18, or trisomy 13. However, in NIPT-positive and indeterminate cases, rare chromosomal disease may become apparent, requiring advanced genetic considerations and counseling skills. We experienced two such cases, a trisomy 21 mosaicism case triggered by NIPT-positive status and 18q deletion syndrome triggered by NIPT-indeterminate status. These cases have two clinical implications for NIPT. First, it was revealed that trisomy mosaicism might be found in NIPT-positive cases that have lower Z-Scores than those inferred from the fraction of fetal cfDNA in the case of standard trisomy. Second, it is possible that microdeletion syndrome could be the reason for an indeterminate NIPT result. Today’s genetic counseling requires more expertise in ethics and communication as well as genetic science because NIPT can lead to totally unexpected results.
キーワード NIPT massively parallel sequencing trisomy 21 mosaicism 18q-deletion syndrome genetic counseling
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2021-12
75巻
6号
出版者 Okayama University Medical School
開始ページ 745
終了ページ 750
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2021 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 34955544
Web of Science KeyUT 000735319800002
NAID 120007180276
フルテキストURL fulltext.pdf
著者 Okamoto, Kazuhiro| Nakamura, Keiichiro| Matsuoka, Hirofumi| Matsubara, Yuko| Haraga, Junko| Ogawa, Chikako| Masuyama, Hisashi|
キーワード gynecological cancer chronic diseases occurrence risk factors
発行日 2020-01-29
出版物タイトル Molecular and Clinical Oncology
12巻
4号
出版者 Spandidos Publications
開始ページ 336
終了ページ 342
ISSN 2049-9450
NCID AA12610944
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © Okamoto et al.
論文のバージョン publisher
PubMed ID 32190316
DOI 10.3892/mco.2020.1989
Web of Science KeyUT 000523727300007
関連URL isVersionOf https://doi.org/10.3892/mco.2020.1989
JaLCDOI 10.18926/AMO/58268
フルテキストURL 74_2_109.pdf
著者 Ogawa, Chikako| Nakamura, Keiichiro| Matsuoka, Hirofumi| Matsubara, Yuko| Haraga, Junko| Masuyama, Hisashi|
抄録 This study aimed to determine whether the risk conferred by gynecologic cancer (GC) as second primary cancer (SPC) differs from that associated with GC as first primary cancer (FPC). We investigated the correlations between FPC/SPC and the characteristics and prognoses of 1,645 GC patients (701 with cervical cancer [CC], 641 with endometrial cancer [EM], and 303 with ovarian cancer [OV]). The χ2 test and the Kaplan–Meier method were used to determine whether FPC/SPC and the characteristics and prognoses of GC patients. Of the SPC patients, 26 (3.7%) had CC, 53 (8.3%) had EM, and 31 (10.2%) had OV. The most common previous cancer type in SPC of GC patients was breast cancer, which was observed in 13 patients (50.0%) with CC, 23 (43.4%) with EM, and 16 (51.6%) with OV. In all patients with CC, EM, and OV as SPC, the stage was significantly associated with recurrence. There were no significant differences in the morbidity or mortality of CC, EM, or OV patients between those with FPC and those with SPC. The risk of SPC development in GC patients varied, ranging from 3.5% (CC) to 10.3% (OV) of patients.
キーワード second primary cancer gynecologic cancer prognosis
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2020-04
74巻
2号
出版者 Okayama University Medical School
開始ページ 109
終了ページ 114
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2020 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 32341584
Web of Science KeyUT 000528278500003
NAID 120006839447
タイトル(別表記) A preoperative SUVmax greater than the ADCmin of the primary tumour : A predictor of disease recurrence and survival in patients with endometrial cancer
フルテキストURL 126_11.pdf
著者 中村 圭一郎| 上者 郁夫| 福島 千加子| 春間 朋子| 林 千晶| 楠本 知行| 関 典子| 本郷 淳司| 平松 祐司|
キーワード endometrial cancer SUVmax PET/CT predictor of poor prognosis
出版物タイトル 岡山医学会雑誌
発行日 2014-04-01
126巻
1号
開始ページ 11
終了ページ 15
ISSN 0030-1558
関連URL http://www.okayama-u.ac.jp/user/oma/
言語 日本語
著作権者 Copyright (c) 2014 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.126.11