| JaLCDOI | 10.18926/AMO/62820 |
|---|---|
| フルテキストURL | 75_6_763.pdf |
| 著者 | Iwata, Takehiro| Sadahira, Takuya| Maruyama, Yuki| Sekito, Takanori| Yoshinaga, Kasumi| Watari, Shogo| Nagao, Kentaro| Kawada, Tatsushi| Tominaga, Yusuke| Nishimura, Shingo| Takamoto, Atsushi| Sako, Tomoko| Edamura, Kohei| Kobayashi, Yasuyuki| Araki, Motoo| Ishii, Ayano| Watanabe, Masami| Watanabe, Toyohiko| Nasu, Yasutomo| Wada, Koichiro| |
| 抄録 | The aim of this ongoing trial is to evaluate the clinical efficacy and safety of sitafloxacin (STFX) 200 mg once daily (QD) for 7 days in patients with refractory genitourinary tract infections, which include recurrent or complicated cystitis, complicated pyelonephritis, bacterial prostatitis, and epididymitis. The primary endpoint is the microbiological efficacy at 5-9 days after the last administration of STFX. Recruitment began in February 2021, and the target total sample size is 92 participants. |
| キーワード | genitourinary tract infections fluoroquinolone resistance extended-spectrum beta-lactamase |
| Amo Type | Clinical Study Protocol |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2021-12 |
| 巻 | 75巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 763 |
| 終了ページ | 766 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2021 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 34955548 |
| Web of Science KeyUT | 000735319800006 |
| NAID | 120007180272 |
| JaLCDOI | 10.18926/AMO/62810 |
|---|---|
| フルテキストURL | 75_6_705.pdf |
| 著者 | Iwata, Takehiro| Maruyama, Yuki| Kawada, Tatsushi| Sadahira, Takuya| Katayama, Satoshi| Takamoto, Atsushi| Sako, Tomoko| Wada, Koichiro| Edamura, Kohei| Kobayashi, Yasuyuki| Araki, Motoo| Watanabe, Masami| Watanabe, Toyohiko| Nasu, Yasutomo| |
| 抄録 | Optimal neoadjuvant hormone therapy (NHT) for reducing prostate cancer (PC) patients’ prostate volume pre-brachytherapy is controversial. We evaluated the differential impact of neoadjuvant gonadotropin-releasing hormone (GnRH) antagonist versus agonist on post-brachytherapy testosterone recovery in 112 patients treated pre-brachytherapy with NHT (GnRH antagonist, n=32; GnRH agonists, n=80) (Jan. 2007-June 2019). We assessed the effects of patient characteristics and a GnRH analogue on testosterone recovery with logistic regression and a propensity score analysis (PSA). There was no significant difference in the rate of testosterone recovery to normal levels (> 300 ng/dL) between the GnRH antagonist and agonists (p=0.07). The GnRH agonists induced a significantly more rapid testosterone recovery rate at 3 months post-brachytherapy versus the GnRH antagonist (p<0.0001); there was no difference in testosterone recovery at 12 months between the GnRH antagonist/agonists (p=0.8). In the multivariate analysis, no actor was associated with testosterone recovery. In the PSA, older age and higher body mass index (BMI) were significantly associated with longer testosterone recovery. Post-brachytherapy testosterone recovery was quicker with the neoadjuvant GnRH agonists than the antagonist, and the testosterone recovery rate was significantly associated with older age and higher BMI. Long-term follow-ups are needed to determine any differential effects of GnRH analogues on the quality of life of brachytherapy-treated PC patients. |
| キーワード | testosterone recovery GnRH antagonist GnRH agonist brachytherapy prostate cancer |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2021-12 |
| 巻 | 75巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 705 |
| 終了ページ | 711 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2021 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 34955538 |
| Web of Science KeyUT | 000735297900006 |
| NAID | 120007180282 |
| フルテキストURL | fulltext20211018-7a.pdf |
|---|---|
| 著者 | Watari, Shogo| Araki, Motoo| Matsumoto, Jun| Yoshinaga, Kasumi| Sekito, Takanori| Maruyama, Yuki| Mitsui, Yosuke| Sadahira, Takuya| Kubota, Risa| Nishimura, Shingo| Wada, Koichiro| Kobayashi, Yasuyuki| Takeuchi, Hidemi| Tanabe, Katsuyuki| Kitagawa, Masashi| Morinaga, Hiroshi| Kitamura, Shinji| Sugiyama, Hitoshi| Ariyoshi, Noritaka| Wada, Jun| Watanabe, Masami| Watanabe, Toyohiko| Nasu, Yasutomo| |
| キーワード | Cytochrome P450 tacrolimus renal transplantation CYP2C19 vonoprazan rabeprazole |
| 備考 | © 2021 The Japanese Society for the Study of Xenobiotics. This manuscript version is made available under the CC-BY-NC-ND 4.0 License.http://creativecommons.org/licenses/by-nc-nd/4.0/.This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.dmpk.2021.100407] .| |
| 発行日 | 2021-10-31 |
| 出版物タイトル | Drug Metabolism and Pharmacokinetics |
| 巻 | 40巻 |
| 出版者 | Elsevier Ltd. |
| 開始ページ | 100407 |
| ISSN | 13474367 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2021 The Japanese Society for the Study of Xenobiotics. Published by Elsevier Ltd. All rights reserved. |
| 論文のバージョン | author |
| PubMed ID | 34352707 |
| DOI | 10.1016/j.dmpk.2021.100407 |
| Web of Science KeyUT | 000702719100002 |
| 関連URL | isVersionOf https://doi.org/10.1016/j.dmpk.2021.100407 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Lin, Wenfeng| Sun, Jingkai| Sadahira, Takuya| Xu, Naijin| Wada, Koichiro| Liu, Chunxiao| Araki, Motoo| Xu, Abai| Watanabe, Masami| Nasu, Yasutomo| Huang, Peng| |
| キーワード | Urothelial bladder cancer doxorubicin cisplatin chemoresistance nitroxoline STAT3 |
| 発行日 | 2021-07-25 |
| 出版物タイトル | International Journal of Biological Sciences |
| 巻 | 17巻 |
| 号 | 12号 |
| 出版者 | Ivyspring International Publisher |
| 開始ページ | 3255 |
| 終了ページ | 3267 |
| ISSN | 1449-2288 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The author(s). |
| 論文のバージョン | publisher |
| DOI | 10.7150/ijbs.63125 |
| Web of Science KeyUT | 000682847000007 |
| 関連URL | isVersionOf https://doi.org/10.7150/ijbs.63125 |
| フルテキストURL | fulltext20210721-2.pdf figure20210721-2.pdf |
|---|---|
| 著者 | Watari, Shogo| Araki, Motoo| Wada, Koichiro| Yoshinaga, Kasumi| Maruyama, Yuki| Mitsui, Yosuke| Sadahira, Takuya| Kubota, Risa| Nishimura, Shingo| Kobayashi, Yasuyuki| Takeuchi, Hidemi| Tanabe, Katsuyuki| Kitagawa, Masashi| Morinaga, Hiroshi| Kitamura, Shinji| Sugiyama, Hitoshi| Wada, Jun| Watanabe, Masami| Watanabe, Toyohiko| Nasu, Yasutomo| |
| 備考 | © 2021 Published by Elsevier Inc. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.transproceed.2021.03.043] . | |
| 発行日 | 2021-4-28 |
| 出版物タイトル | Transplantation Proceedings |
| 巻 | 53巻 |
| 号 | 5号 |
| 出版者 | Elsevier BV |
| 開始ページ | 1494 |
| 終了ページ | 1500 |
| ISSN | 0041-1345 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 論文のバージョン | author |
| PubMed ID | 33931247 |
| DOI | 10.1016/j.transproceed.2021.03.043 |
| Web of Science KeyUT | 000668604400017 |
| 関連URL | isVersionOf https://doi.org/10.1016/j.transproceed.2021.03.043 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Yoshinaga, Kasumi| Araki, Motoo| Wada, Koichiro| Sekito, Takanori| Watari, Shogo| Maruyama, Yuki| Mitsui, Yosuke| Sadahira, Takuya| Kubota, Risa| Nishimura, Shingo| Edamura, Kohei| Kobayashi, Yasuyuki| Tanabe, Katsuyuki| Takeuchi, Hidemi| Kitagawa, Masashi| Kitamura, Shinji| Wada, Jun| Watanabe, Masami| Watanabe, Toyohiko| Nasu, Yasutomo| |
| キーワード | diabetes mellitus kidney function kidney transplantation marginal donor |
| 発行日 | 2021-06-08 |
| 出版物タイトル | Immunity Inflammation and Disease |
| 出版者 | Wiley |
| ISSN | 2050-4527 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2021 The Authors. |
| 論文のバージョン | publisher |
| PubMed ID | 34102025 |
| DOI | 10.1002/iid3.470 |
| NAID | 120007053366 |
| Web of Science KeyUT | 000658836600001 |
| 関連URL | isVersionOf https://doi.org/10.1002/iid3.470 |
| タイトル（別表記） | Telemedicine in urology |
|---|---|
| フルテキストURL | 133_73.pdf |
| 著者 | 富永 悠介| 荒木 元朗| 那須 保友| |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2021-04-01 |
| 巻 | 133巻 |
| 号 | 1号 |
| 開始ページ | 73 |
| 終了ページ | 75 |
| ISSN | 0030-1558 |
| 関連URL | isVersionOf https://doi.org/10.4044/joma.133.73 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2021 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.133.73 |
| NAID | 130008034819 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Lin, Wenfeng| Li, Chaoming| Xu, Naijin| Watanabe, Masami| Xue, Ruizhi| Xu, Abai| Araki, Motoo| Sun, Ruifen| Liu, Chunxiao| Nasu, Yasutomo| Huang, Peng| |
| キーワード | prostate cancer PLGA indocyanine green resiquimod photothermal therapy immunotherapy |
| 発行日 | 2021-04-12 |
| 出版物タイトル | International Journal of Nanomedicine |
| 巻 | 16巻 |
| 出版者 | Dove Medical Press Ltd. |
| 開始ページ | 2775 |
| 終了ページ | 2787 |
| ISSN | 1178-2013 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2021 Lin et al. |
| 論文のバージョン | publisher |
| PubMed ID | 33880023 |
| DOI | 10.2147/IJN.S301552 |
| NAID | 120007034434 |
| Web of Science KeyUT | 000639251200001 |
| 関連URL | isVersionOf https://doi.org/10.2147/IJN.S301552 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Wada, Koichiro| Araki, Motoo| Tanimoto, Ryuta| Sadahira, Takuya| Watari, Shogo| Maruyama, Yuki| Mitsui, Yosuke| Nakajima, Hirochika| Acosta, Herik| Katayama, Satoshi| Iwata, Takehiro| Nishimura, Shingo| Takamoto, Atsushi| Sako, Tomoko| Edamura, Kohei| Kobayashi, Yasuyuki| Watanabe, Masami| Watanabe, Toyohiko| Nasu, Yasutomo| |
| キーワード | Photodynamic diagnosis 5-Aminolevulinic acid ALA-PDD Upper urinary tract urothelial carcinoma VISERA ELITE video system |
| 発行日 | 2021-03-25 |
| 出版物タイトル | BMC urology |
| 巻 | 21巻 |
| 号 | 1号 |
| 出版者 | BMC |
| 開始ページ | 45 |
| ISSN | 1471-2490 |
| NCID | AA12035460 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2021. |
| 論文のバージョン | publisher |
| PubMed ID | 33765999 |
| DOI | 10.1186/s12894-021-00819-2 |
| NAID | 120007008530 |
| Web of Science KeyUT | 000632906900001 |
| 関連URL | isVersionOf https://doi.org/10.1186/s12894-021-00819-2 |
| フルテキストURL | fulltext.pdf Fig_1.pptx Fig_2.pptx |
|---|---|
| 著者 | Maruyama, Yuki| Araki, Motoo| Wada, Koichiro| Yoshinaga, Kasumi| Mitsui, Yosuke| Sadahira, Takuya| Nishimura, Shingo| Edamura, Kohei| Kobayashi, Yasuyuki| Watanabe, Masami| Watanabe, Toyohiko| Monga, Manoj| Nasu, Yasutomo| Kumon, Hiromi| |
| キーワード | urothelial carcinoma urinary tract cancer ureteroscopy long-term survival renal pelvis ureter |
| 備考 | This is a pre-copyedited, author-produced version of an article accepted for publication in Japanese Journal of Clinical Oncology following peer review. The version of record Long-term ureteroscopic management of upper tract urothelial carcinoma: 28-year single-centre experience, Japanese Journal of Clinical Oncology, Volume 51, Issue 1, January 2021, Pages 130–137 is available online at: https://doi.org/10.1093/jjco/hyaa132.| |
| 発行日 | 2020-7-27 |
| 出版物タイトル | Japanese Journal of Clinical Oncology |
| 巻 | 51巻 |
| 号 | 1号 |
| 出版者 | Oxford University Press |
| 開始ページ | 130 |
| 終了ページ | 137 |
| ISSN | 0368-2811 |
| NCID | AA00690866 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 論文のバージョン | author |
| PubMed ID | 32715306 |
| DOI | 10.1093/jjco/hyaa132 |
| Web of Science KeyUT | 000608420900018 |
| 関連URL | isVersionOf https://doi.org/10.1093/jjco/hyaa132 |
| JaLCDOI | 10.18926/AMO/60806 |
|---|---|
| フルテキストURL | 74_5_443.pdf |
| 著者 | Sekito, Takanori| Araki, Motoo| Hiraki, Takao| Uka, Mayu| Komaki, Toshiyuki| Matsui, Yusuke| Iguchi, Toshihiro| Katayama, Satoshi| Yoshinaga, Kasumi| Watari, Shogo| Maruyama, Yuki| Mitsui, Yosuke| Kubota, Risa| Sadahira, Takuya| Nishimura, Shingo| Wada, Koichiro| Takamoto, Atsushi| Edamura, Kohei| Sako, Tomoko| Kobayashi, Yasuyuki| Watanabe, Toyohiko| Kanazawa, Susumu| Nasu, Yasutomo| |
| 抄録 | We report a 47-year-old Japanese female with 10 previous treatments for multiple bilateral renal cell carcinoma (RCC) associated with von Hippel-Lindau disease. The 14-mm right lower pole renal tumor was in contact with the right ureter. Laparoscopic cryoablation was performed to protect the ureter wrapped with gauze. Computed tomography (CT) monitoring was used to confirm the precise ≥ 6 mm ice-ball margin. There was no local progression at 6-months post-surgery. The serum creatinine has been stable. This is apparently the first report of combined laparoscopic and CT monitoring of an ice-ball formation and its margin during cryoablation for RCC. |
| キーワード | laparoscopic cryoablation multiple renal masses nephron-sparing surgery renal cell carcinoma von Hippel-Lindau disease |
| Amo Type | Case Report |
| 備考 | Fig. 1B is replaced on Dec. 23, 2020.| |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2020-10 |
| 巻 | 74巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 443 |
| 終了ページ | 448 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2020 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 33106702 |
| Web of Science KeyUT | 000581970100011 |
| NAID | 120006892932 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Xu, Naijin| Lin, Wenfeng| Sun, Jingkai| Sadahira, Takuya| Xu, Abai| Watanabe, Masami| Guo, Kai| Araki, Motoo| Li, Gonghui| Liu, Chunxiao| Nasu, Yasutomo| Huang, Peng| |
| キーワード | Nitroxoline Bladder cancer EMT immunotherapy preclinical model |
| 発行日 | 2020-09-23 |
| 出版物タイトル | Journal of Cancer |
| 巻 | 11巻 |
| 号 | 22号 |
| 出版者 | Ivyspring International Publisher |
| 開始ページ | 6633 |
| 終了ページ | 6641 |
| ISSN | 1837-9664 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The author(s). |
| 論文のバージョン | publisher |
| PubMed ID | 33046984 |
| DOI | 10.7150/jca.47025 |
| Web of Science KeyUT | 000575099000017 |
| 関連URL | isVersionOf https://doi.org/10.7150/jca.47025 |
| JaLCDOI | 10.18926/AMO/57953 |
|---|---|
| フルテキストURL | 74_1_53.pdf |
| 著者 | Kubota, Risa| Araki, Motoo| Wada, Koichiro| Kawamura, Kasumi| Maruyama, Yuki| Mitsui, Yosuke| Sadahira, Takuya| Ariyoshi, Yuichi| Iwata, Takehiro| Nishimura, Shingo| Takamoto, Atsushi| Sako, Tomoko| Edamura, Kohei| Kobayashi, Yasuyuki| Kano, Yuzuki| Kitagawa, Masashi| Tanabe, Katsuyuki| Sugiyama, Hitoshi| Wada, Jun| Watanabe, Masami| Watanabe, Toyohiko| Nasu, Yasutomo| |
| 抄録 | We investigated the feasibility of robotic renal autotransplantation (RAT) in a porcine model to reduce invasiveness of RAT. Five pigs underwent robotic RAT using the da Vinci® robotic system. A robotic left nephrectomy was performed in all cases. Robotic RAT was performed on the left side in all but one case. Four ports were used. In 3 cases, the kidney was taken out through the GelPort® and irrigated on ice with Ringer’s solution. In 2 cases, a complete intracorporeal robotic RAT was performed. An end-to-side anastomosis was performed between the renal vein and the external iliac vein and between the renal artery and the external iliac artery. Ureteroneocystostomy was also performed in 2 cases. All cases were performed robotically without open conversion. The median (IQR) console time was 3.1 (0.7) h, and the operative time was 3.8 (1.1) h. The estimated blood loss was 30 (0) ml. The warm ischemia time was 4.0 (0.2) min, and the cold ischemia time was 97 (17) min. Intracorporeal transarterial hypothermic renal perfusion was feasible in the 2 complete intracorporeal robotic RAT cases by using a perfusion catheter through a laparoscopic port. Robotic RAT has the potential to be a new minimally invasive substitute for conventional open surgery. |
| キーワード | renal autotransplantation robotic porcine model transplantation |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2020-02 |
| 巻 | 74巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 53 |
| 終了ページ | 58 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2020 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 32099249 |
| Web of Science KeyUT | 000516606200008 |
| NAID | 120006795620 |
| JaLCDOI | 10.18926/AMO/56871 |
|---|---|
| フルテキストURL | 73_3_269.pdf |
| 著者 | Tsuboi, Ichiro| Araki, Motoo| Fujiwara, Hiroyasu| Iguchi, Toshihiro| Hiraki, Takao| Arichi, Naoko| Kawamura, Kasumi| Maruyama, Yuki| Mitsui, Yosuke| Sadahira, Takuya| Kubota, Risa| Nishimura, Shingo| Sako, Tomoko| Takamoto, Atsushi| Wada, Koichiro| Kobayashi, Yasuyuki| Watanabe, Toyohiko| Yanai, Hiroyuki| Kitagawa, Masashi| Tanabe, Katsuyuki| Sugiyama, Hitoshi| Wada, Jun| Shiina, Hiroaki| Kanazawa, Susumu| Nasu, Yasutomo| |
| 抄録 | Nephron-sparing treatment should be offered whenever possible to avoid dialysis in allograph cases. Cryoablation is a new treatment option for treating small-sized renal cell cancer (RCCs). We report a case of RCC arising in a kidney allograft treated by cryoablation. To our knowledge, this is the first case in Asia of RCC in a renal allograft treated using cryoablation. Contrast-enhanced CT-guided percutaneous renal needle biopsy and cryoablation were used to identify the RCC, which could not be identified by other techniques. The postoperative course was uneventful. Contrast-enhanced CT also showed no recurrence or metastases at the 6-month follow-up. |
| キーワード | cryoablation partial nephrectomy renal cell carcinoma renal allograft renal transplantation |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2019-06 |
| 巻 | 73巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 269 |
| 終了ページ | 272 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2019 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 31235976 |
| JaLCDOI | 10.18926/AMO/55445 |
|---|---|
| フルテキストURL | 71_5_449.pdf |
| 著者 | Mitsui, Yosuke| Wada, Koichiro| Araki, Motoo| Yoshioka, Takashi| Ariyoshi, Yuichi| Nishimura, Shingo| Kobayashi, Yasuyuki| Sasaki, Katsumi| Watanabe, Toyohiko| Nasu, Yasutomo| |
| 抄録 | We describe a 40-year-old living-donor renal-transplant recipient who underwent successful ureterolithotripsy. He had been on hemodialysis for >15 years pre-transplant and underwent ureteroureterostomy along with the surgery. One year post-transplant, ultrasound examination demonstrated hydronephrosis, and CT showed a 6-mm ureteral calculus at the ureteroureterostomy site. No pain and no elevated serum creatinine were present. As the ureter was easily accessed, we performed a ureterolithotripsy, which would confirm whether a suture caused the calculus. Despite ureteral tortuosity, laser stone fragmentation succeeded. The calculus was completely removed with an antegrade guidewire. Mild postoperative ureteral stenosis resolved with a temporary ureteral stent without balloon dilation. Ureterolithotripsy is effective even in renal transplant recipients with ureteroureterostomy. |
| キーワード | lithotripsy recipient renal transplant ureteroscopy ureteral stone |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2017-10 |
| 巻 | 71巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 449 |
| 終了ページ | 452 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2017 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 29042705 |
| JaLCDOI | 10.18926/AMO/55313 |
|---|---|
| フルテキストURL | 71_4_351.pdf |
| 著者 | Araki, Motoo| Wada, Koichiro| Mitsui, Yosuke| Sadahira, Takuya| Kubota, Risa| Nishimura, Shingo| Yoshioka, Takashi| Ariyoshi, Yuichi| Fujio, Kei| Takamoto, Atsushi| Sugimoto, Morito| Sasaki, Katsumi| Kobayashi, Yasuyuki| Ebara, Shin| Taninishi, Hideki| Amano, Hiroyuki| Inui, Masashi| Watanabe, Masami| Watanabe, Toyohiko| Nasu, Yasutomo| |
| 抄録 | A 38-year-old woman with a 2.7-cm left ureteral stenosis requiring chronic ureteral stent exchange elected to undergo robotic renal autotransplantation. Left ureteropelvic junction obstruction (UPJO) was also suspected. Robotic donor nephrectomy contributed to the fine dissection for desmoplastic changes. The kidney was removed through a Gelport and examined on ice. UPJO was not seen. An end-to-side robotic anastomosis was created between the renal and external iliac vessels. The console time was 507 min, and the warm ischemia time was 4 min 5 sec. She became stent-free. Robotic renal autotransplantation is a new, minimally invasive approach to renal preservation. |
| キーワード | robotic surgery renal autotransplantation ureteral stenosis laparoscopic surgery renal transplantation |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2017-08 |
| 巻 | 71巻 |
| 号 | 4号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 351 |
| 終了ページ | 355 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2017 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 28824192 |
| JaLCDOI | 10.18926/AMO/55205 |
|---|---|
| フルテキストURL | 71_3_227.pdf |
| 著者 | Sasaki, Katsumi| Wada, Koichiro| Araki, Motoo| Kobayashi, Yasuyuki| Sugimoto, Morito| Ebara, Shin| Watanabe, Toyohiko| Nasu, Yasutomo| |
| 抄録 | We elucidate the fate of cases clinically suspected of carcinoma in situ (Cis) of the upper tract with serial ureteroscopy. Of 143 patients who underwent ureteroscopy for suspected upper tract urothelial carcinoma (UTUC) between January 2008 and February 2016, 12 cases with consistently positive urine cytology and poorly detectable upper-tract malignancies by imaging were reviewed. In these 12 patients, 19 ureteroscopy procedures (25 renal units) were performed. Vesical random biopsy was performed before the 1st ureteroscopy to exclude malignancy of the bladder in all 12 cases. Median follow-up was 42 (13-67) months. Positive biopsy results at the 1st ureteroscopy were obtained in 3 (25%) patients and all were diagnosed wth Cis of the upper tract. Two (17%) of 9 patients who were negative or inconclusive at the 1st ureteroscopy were finally diagnosed as UTUC, but plural ureteroscopy procedures were needed for the diagnoses in both. Carcinoma of the bladder appeared in 5 (42%) patients during follow-up, despite the earlier ruling out of vesical malignancy. Four (33%) of those 5 patients never developed upper-tract urothelial carcinoma during follow-up. Caution is required before undertaking radical surgery for cases clinically suspected of Cis of the upper tract. In our experience, only 42% of such patients developed UTUC; another 33% eventually developed carcinoma of the bladder without UTUC. |
| キーワード | carcinoma in situ carcinoma of the bladder upper tract urothelial carcinoma ureteroscopy urine cytology |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2017-06 |
| 巻 | 71巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 227 |
| 終了ページ | 232 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2017 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 28655942 |
| JaLCDOI | 10.18926/AMO/54989 |
|---|---|
| フルテキストURL | 71_2_187.pdf |
| 著者 | Takamoto, Atsushi| Araki, Motoo| Wada, Koichiro| Sugimoto, Morito| Kobayashi, Yasuyuki| Sasaki, Katsumi| Watanabe, Toyohiko| Nasu, Yasutomo| |
| 抄録 | We report the case of a 58-year-old Japanese man with bilateral synchronous renal cell carcinoma (RCC). The diameters of the right and left tumors were 56 and 69 mm, respectively. Both tumors were endophytic. Cryoablation with prophylactic embolization was performed for the left tumor, and 1 month later, a right open partial nephrectomy was performed. No recurrence was observed during a 16-month follow-up, and the serum creatinine level has been stable. The prognosis of bilateral synchronous RCC is better than that of dialysis patients. The novel approach of combining cryoablation and partial nephrectomy can achieve good cancer control and renal function in bilateral RCC. |
| キーワード | cryoablation multiple renal masses nephron-sparing surgery renal cell carcinoma synchronous multiple primary |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2017-04 |
| 巻 | 71巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 187 |
| 終了ページ | 190 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2017 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 28420902 |
| JaLCDOI | 10.18926/AMO/54508 |
|---|---|
| フルテキストURL | 70_4_299.pdf |
| 著者 | Wada, Koichiro| Uehara, Shinya| Ishii, Ayano| Sadahira, Takuya| Yamamoto, Masumi| Mitsuhata, Ritsuko| Takamoto , Atsushi| Araki, Motoo| Kobayashi, Yasuyuki| Watanabe, Masami| Watanabe, Toyohiko| Hotta, Katsuyuki| Nasu, Yasutomo| |
| 抄録 | Urinary tract infections (UTIs) are the most common bacterial infections in women, and many patients experience frequent recurrence. The aim of this report is to introduce an on-going prospective phase II clinical trial performed to evaluate the preventive effectiveness of Lactobacillus vaginal suppositories for prevention of recurrent cystitis. Patients enrolled in this study are administered vaginal suppositories containing the GAI 98322 strain of Lactobacillus crispatus every 2 days or 3 times a week for one year. The primary endpoint is recurrence of cystitis and the secondary endpoints are adverse events. Recruitment began in December 2013 and target sample size is 20 participants. |
| キーワード | probiotics lactobacilli Lactobacillus crispatus urinary tract infection vaginal suppository |
| Amo Type | Clinical Study Protocols |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2016-08 |
| 巻 | 70巻 |
| 号 | 4号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 299 |
| 終了ページ | 302 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2016 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 27549677 |
| Web of Science KeyUT | 000384748600012 |
| JaLCDOI | 10.18926/AMO/54507 |
|---|---|
| フルテキストURL | 70_4_295.pdf |
| 著者 | Araki, Motoo| Wada, Koichiro| Mitsui, Yosuke| Kubota, Risa| Yoshioka, Takashi| Ariyoshi, Yuichi| Kobayashi, Yasuyuki| Kitagawa, Masashi| Tanabe, Katsuyuki| Sugiyama, Hiroshi| Wada, Jun| Watanabe, Masami| Watanabe, Toyohiko| Hotta, Katsuyuki| Nasu, Yasutomo| |
| 抄録 | Although graft survival following renal transplantation (RTx) has improved, outcomes following highrisk RTx are variable. Preexisting antibodies, including donor-specific antibodies (DSA), play an important role in graft dysfunction and survival. We have designed a study to investigate the safety and efficacy of anti-CD20 monoclonal antibodies (rituximab) in high-risk RTx recipients. Major eligibility criteria include: 1) major and minor ABO blood group mismatch, 2) positive DSA. Thirty-five patients will receive 200 mg/body of rituximab. The primary endpoint is the incidence of B cell depletion. This study will clarify whether rituximab is efficacious in improving graft survival in high-risk RTx recipients. |
| キーワード | end-stage renal disease immunosuppression kidney transplantation |
| Amo Type | Clinical Study Protocols |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2016-08 |
| 巻 | 70巻 |
| 号 | 4号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 295 |
| 終了ページ | 297 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2016 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 27549676 |
| Web of Science KeyUT | 000384748600011 |