STUDIES ON VITRIOL SPRINGS (4) ON THE COPPER, ZINC, NICKEL, AND COBALT CONTENTS OF BLOOD AFTER THE INTERNAL USE OF A VITRIOL WATER
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大島 良雄 岡山大学温泉研究所
芦沢 峻 岡山大学温泉研究所
Sotozono proved that the administration of daily 20cc of Fujino Mineral Water (an acid vitriol water containing copper, zinc, nickel and cobalt) has a remarkably beneficial effect on several kinds of hypochromic anemia. It contains 9.56gms of iron, 0.007gm of zinc, 0.005gm of copper 0.001gm of nickel, and 0.006gm of cobalt in one liter. 20 - 40cc of Fujino water was diluted 5 - 10 fold with plain water and administered to the fasting patients perorally. Blood samples were taken from cubital vein before, 1, 2, 4, 6, 24, 48, and 72 hours after the intake of the vitriol water. Copper, zinc, nickel and cobalt contents of the blood samples were measured by Ashizawa' s dithizone- chromatographic method. It was shown that copper, nickel, and cobalt contents of blood rose unexpectedly high temporarily, in a manner that did not correspond to their amount in the given mineral water. So that the mobilization of copper, nickel, and cobalt in the body after the intake of the mineral IVrter was susrected. Zinc content of blood showed no constant tendency.
Institute for Thermal Spring Research, Okayama University
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