| JaLCDOI | 10.18926/AMO/32899 |
|---|---|
| フルテキストURL | fulltext.pdf |
| 著者 | Hosogi, Mizuho| Okada, Ayumi| Yamanaka, Eriko| Ootyou, Keiko| Tsukamoto, Chiaki| Morishima, Tsuneo| |
| 抄録 | Self-esteem is the evaluative feelings one holds for oneself and the sense that one has essential worth. It is evaluated as the difference between the actual self and the ideal self. Healthy self-esteem supports psychological stability and positive social activity and is an essential element in the psychological development of children. The purpose of this study was to evaluate self-esteem in children with psychosomatic symptoms and elucidate a strategy for using such evaluations in therapy. We evaluated self-esteem in 56 patients at the Department of Pediatrics of Okayama University Hospital who were undergoing outpatient therapy for psychosomatic symptoms, using Pope's 5-scale test of self-esteem for children. We examined patient attributes, course of therapy, and social adjustment. Patients with low self-esteem on multiple scales at the first visit were all female, and these patients had a significantly higher frequency of family function problems, such as a family member with a psychiatric disorder, economic hardship, or experience of child abuse. Moreover, the prognosis for these patients was poor regardless of their social adjustment at the first visit. |
| キーワード | self-esteem psychosomatic symptom family function child abuse 5-scale test of self-esteem |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2007-10 |
| 巻 | 61巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 271 |
| 終了ページ | 281 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 17971844 |
| Web of Science KeyUT | 000250431700005 |
| JaLCDOI | 10.18926/AMO/32898 |
|---|---|
| フルテキストURL | fulltext.pdf |
| 著者 | Matsuo, Toshihiko| Masuda, Ikuya| Ota, Kosuke| Yamadori, Ichiro| Sunami, Reiko| Nose, Soichiro| |
| 抄録 | We describe herein 2 patients who developed Vogt-Koyanagi-Harada syndrome in the course of renal biopsy-proven immunoglobulin A (IgA) nephropathy. A 61-year-old man with an 11-year history of IgA nephropathy and a 16-year history of thyroiditis, and a 56-year-old man with a 5-year history of IgA nephropathy developed Vogt-Koyanagi-Harada syndrome. At the time of the eye disease presentation, IgA nephropathy was stable without corticosteroids in both patients. Vogt-Koyanagi-Harada syndrome was successfully treated with intravenous administration of prednisolone tapered from 200 mg daily. Vogt-Koyanagi-Harada syndrome is associated with IgA nephropathy, suggesting a similar autoimmune mechanism for both diseases. |
| キーワード | immunoglobulin A (IgA) nephropathy Vogt-Koyanagi-Harada syndrome (disease) |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2007-10 |
| 巻 | 61巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 305 |
| 終了ページ | 309 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 17971847 |
| Web of Science KeyUT | 000250431700008 |
| JaLCDOI | 10.18926/AMO/32897 |
|---|---|
| フルテキストURL | fulltext.pdf |
| 著者 | Matsukawa, Akihiro| |
| 抄録 | The innate immune system provides immediate defense against infection and serves as the first line of host defense during infection. In innate immunity, leukocytes such as neutrophils and macrophages recognize and respond to pathogens in a non-specific manner. Therefore, the recruitment and activation of leukocytes are essential in innate immunity, and are governed by a variety of chemical mediators including cytokines. Cytokines are generally divided into 2 types, termed type-1 and type-2 cytokines. Type-1 cytokines are important in local host defense, while type-2 cytokines play a protective role when inflammatory response spreads to the body. These cytokines exert their biological functions through the janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway. STAT1/3/4/6 are transcription factors that mediate IFNgamma/IL-10/IL-12/IL-13 cytokine signaling, respectively. Evidence indicates that STAT proteins have a significant impact on innate immunity during sepsis. This review focuses on recent understandings in the regulation of innate immunity by STAT proteins during sepsis and septic shock. The suppressor of cytokine signaling (SOCS) proteins are a family of SH2 domain-containing cytoplasmic proteins that complete a negative feedback loop to attenuate signal transduction from cytokines that act through the JAK/STAT pathway. The participation of SOCS proteins in sepsis is also discussed. |
| キーワード | cytokines innate immunity sepsis SOCS STAT |
| Amo Type | Review |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2007-10 |
| 巻 | 61巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 239 |
| 終了ページ | 245 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 17971840 |
| Web of Science KeyUT | 000250431700001 |
| JaLCDOI | 10.18926/AMO/32896 |
|---|---|
| フルテキストURL | fulltext.pdf |
| 著者 | Okada, Ayumi| Tsukamoto, Chiaki| Hosogi, Mizuho| Yamanaka, Eriko| Watanabe, Kumi| Ootyou, Keiko| Morishima, Tsuneo| |
| 抄録 | Phagophobia is a disorder characterized by a conditioned excessive fear of eating and is initiated by an event such as vomiting or choking. During childhood, vomiting often occurs as a result of infection or overeating, and painful experiences bring about maladaptive eating behavior like food refusal. There have been few reports of phagophobia, and patients have sometimes been misdiagnosed with anorexia nervosa (AN). The objective of this study was to elucidate the psycho-pathology and current treatment of patients with phagophobia by analyzing case studies. We describe 6 cases with phagophobia. Patients with strong obsessions were refractory to treatment, indicating that evaluation of premorbid personality is crucial to the prognosis. It is important to classify this disorder according to psycho-pathology into "post-traumatic type" and "gain-from-illness type" to make a treatment plan. A solution focused approach is also effective for patients and their family. Paying close attention to these conditions and to the diagnostic concept referred as "hagophobia" is useful in achieving these aims. |
| キーワード | phagophobia functional dysphagia eating disorder premorbid character solution focused approach |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2007-10 |
| 巻 | 61巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 261 |
| 終了ページ | 269 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 17971843 |
| Web of Science KeyUT | 000250431700004 |
| JaLCDOI | 10.18926/AMO/32895 |
|---|---|
| フルテキストURL | fulltext.pdf |
| 著者 | Miyatake, Nobuyuki| Saito, Takeshi| Wada, Jun| Nishikawa, Hidetaka| Matsumoto, Sumiko| Miyachi, Motohiko| Fujii, Masafumi| Makino, Hirofumi| Numata, Takeyuki| |
| 抄録 | We evaluated the linkage between oxygen uptake at the ventilatory threshold (VT) and muscle strength in subjects with and without metabolic syndrome. We used data of 226 Japanese men with metabolic syndrome and 265 Japanese men without the syndrome. Metabolic syndrome has recently been defined by a new criterion in Japan. Oxygen uptake at VT and muscle strength, i.e. grip strength and leg strength were measured. Oxygen uptake at VT and muscle strength/body weight were found to be significantly lower in subjects with metabolic syndrome than in those without the syndrome. However, the differences did not reach significant levels after adjusting for leg strength/body weight or oxygen uptake at VT. A combination of aerobic exercise and resistance training might be considered for preventing and improving metabolic syndrome. |
| キーワード | metabolic syndrome oxygen uptake ventilatory threshold muscle strength |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2007-10 |
| 巻 | 61巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 255 |
| 終了ページ | 259 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 17971842 |
| Web of Science KeyUT | 000250431700003 |
| JaLCDOI | 10.18926/AMO/32894 |
|---|---|
| フルテキストURL | fulltext.pdf |
| 著者 | Mifune, Hirofumi| Akaki, Shiro| Ida, Kentaro| Sei, Tetsuro| Kanazawa, Susumu| Okada, Hiroyuki| |
| 抄録 | <P>To evaluate the ability of multidetector-row CT (MDCT) to predict a risk of hemorrhage in patients with esophageal varices, a total of 40 MDCT scans were performed in 29 patients who had been diagnosed with esophageal varices by conventional upper gastrointestinal tract endoscopy. In 11 patients, MDCT was performed both before and after endoscopic injection sclerotherapy (EIS). Endoscopically, the red color sign (RC sign) was present in 28 scans. Of the 11 patients who underwent EIS, the RC sign disappeared after EIS in 9. The MDCT scans were obtained in the arterial, portal, and equilibrial phases, and the portal phase images were used in this study. Subsequently, the extent of esophageal varices was categorized into four MDCT scores. The variceal score, the maximum short axis of the varices, and the presence of palisade vein dilatation obtained from MDCT had significant correlation with endoscopic variceal forms, and the presence and severity of RC sign, respectively (p<0.01). All cases with a maximum minor axis of more than 4 mm showed positive RC sign. MDCT was useful in the evaluation of esophageal varices for predicting a risk of hemorrhage. |
| キーワード | esophageal varices red color sign MDCT |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2007-10 |
| 巻 | 61巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 247 |
| 終了ページ | 254 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 17971841 |
| Web of Science KeyUT | 000250431700002 |
| JaLCDOI | 10.18926/AMO/32893 |
|---|---|
| フルテキストURL | fulltext.pdf |
| 著者 | Ashizawa, Tatsuto| Hama, Koichiro| Tanaka, Hiroaki| Ando, Masayuki| |
| 抄録 | A 64-year-old woman was admitted to our hospital with lower abdominal pain. Routine laboratory values were unremarkable except for the white blood cell count (15,000/micro litter) and the C-reactive protein (CRP) value (22.5 mg/dl). A Computed tomography (CT) scan revealed air collection in the middle of the anterior pararenal space. One day later, CT revealed air collection in the anterior pararenal space spread to the right side and abscess in the sigmoid mesentery. Because an intramesocolic perforation of the sigmoid colon was suspected, an emergency operation was performed. Abscess formation was recognized in the sigmoid mesentery, and sigmoidectomy including the contaminated mesentery and Hartmann.s procedure were performed. The perforation was 3 cm in diameter, and some diverticula were present in the vicinity of the perforated site. The specimen microscopically revealed perforation at the edge of the diverticulum in association with sudden disruption of the proper muscle layer. Based on pathological findings, intramesocolic diverticular perforation of the sigmoid colon was diagnosed. The present case is a very rare condition. However, it was possible to make a diagnosis preoperatively by detecting air collection in the anterior pararenal space on CT scan. If a sigmoid perforation occurs between the leaves of the mesocolon, air extends into the root of the sigmoid mesocolon and within the anterior pararenal space. |
| キーワード | colon diverticulosis intramesocolic perforation computed tomography free air |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2007-10 |
| 巻 | 61巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 299 |
| 終了ページ | 303 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 17971846 |
| Web of Science KeyUT | 000250431700007 |
| JaLCDOI | 10.18926/AMO/32892 |
|---|---|
| フルテキストURL | fulltext.pdf |
| 著者 | Takagi, Koji| Yamada, Teruo| Miki, Yukari| Umegaki, Teruo| Nishimura, Makoto| Sasaki, Junzo| |
| 抄録 | To clarify the development of follicular growth and atresia in the immature ovary, rats. ovaries and blood were removed at fixed points during the period from 0 to 35 days after birth (Day 0 to Day 35). The ovaries were immunohistochemically examined, and blood concentrations of serum follicle-stimulating hormone (FSH) and estrogen (E) were measured. We investigated how time-course changes in follicular cell proliferation, estrogen receptor β (ERβ), apoptosis, and FSH and E concentrations are connected with follicular growth and atresia. Apoptosis was found in the ova from Day 0 to Day 3. On Day 15, apoptosis occurred in some granulosa cell nuclei in some follicles, but BrdU uptake and the presence of cyclin D2 and ER β could be observed in other granulosa cells. From Day 17, apoptosis increased in the follicular granulosa cells, and BrdU uptake and the presence of cyclin D2 and ERβ were decreased. Follicular atresia continued, reaching a peak on Day 30. Serum FSH and E concentrations increased until Day 15, then markedly decreased after Day 17. The mechanism of apoptosis in the ova from Day 0 to 3 has not been clarified. However, the onset of follicular atresia was caused by apoptotic degeneration from Days 15 to 17. These results showed that the oocytes were selected by apoptosis at 2 points in the time-course of the maturation of the ovary. |
| キーワード | histology apoptosis proliferation estrogen follicle-stimulating hormone |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2007-10 |
| 巻 | 61巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 283 |
| 終了ページ | 298 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 17971845 |
| Web of Science KeyUT | 000250431700006 |