ID | 31701 |
JaLCDOI | |
フルテキストURL | |
著者 |
Willmore, L. James
Saint Louis University of Medicine
Ueda, Yuto
Miyazaki Medical College
|
抄録 | Genetic and molecular biological methodologies are being applied to the study of patients with epilepsy at an ever-increasing pace. Accurate classification of epilepsy within large families has allowed identification of genes through linkage analysis and then isolation of gene products. Mutations causing ion channel abnormalities coupled with clinical patterns of focal epilepsy syndromes are beginning to change our thinking about the etiology of recurrent seizures in all patients. Molecular methodology is beginning to have impact on understanding of the mechanisms of actions of drugs used to treat epilepsy and will have an impact on how future treatments are designed. |
キーワード | molecular
genetic
epilepsy
glutamate
transporter
|
Amo Type | Review
|
出版物タイトル |
Acta Medica Okayama
|
発行日 | 2002-04
|
巻 | 56巻
|
号 | 2号
|
出版者 | Okayama University Medical School
|
開始ページ | 57
|
終了ページ | 68
|
ISSN | 0386-300X
|
NCID | AA00508441
|
資料タイプ |
学術雑誌論文
|
言語 |
英語
|
論文のバージョン | publisher
|
査読 |
有り
|
PubMed ID | |
Web of Science KeyUT |