ID | 30880 |
JaLCDOI | |
フルテキストURL | |
著者 |
Yoshida, Shigeko
Okayama University
Akagi, Rriko
Okayama University
Ubuka, Toshihiko
Okayama University
|
抄録 | Excretion of sulfate and taurine, two major metabolites of sulfur, was examined in rats to study the nutritional status of sulfur metabolism in the mammals. Rats maintained on a conventional laboratory diet excreted 1.83 +/- 0.14 mmol of free sulfate and 229.0 +/- 75.3 mumol of taurine/kg of body weight per day. When the diet was changed to a synthetic 25% casein diet, the taurine excretion decreased to 15% of the previous daily excretion, but sulfate excretion decreased only slightly. These decreased levels returned to the original levels when 5 mmol of L-cysteine/kg of body weight was administered into the stomach through a catheter. One week after the first L-cysteine administration, when sulfate and taurine excretion had returned to the original levels, 5 mmol of L-cysteine/kg of body weight was administered likewise. The rats excreted sulfur corresponding to about 95% of L-cysteine administered in the form of free sulfate and taurine within a few days following L-cysteine administration, and sulfate excretion was 3.5 times more than taurine excretion. These results seem to suggest that, in rats, sulfur metabolism is in a state of equilibrium and that sulfate is formed preferentially to taurine. |
キーワード | sulfate
taurine
cysteine
sulfur metabolism
|
Amo Type | Article
|
出版物タイトル |
Acta Medica Okayama
|
発行日 | 1989-10
|
巻 | 43巻
|
号 | 5号
|
出版者 | Okayama University Medical School
|
開始ページ | 281
|
終了ページ | 288
|
ISSN | 0386-300X
|
NCID | AA00508441
|
資料タイプ |
学術雑誌論文
|
言語 |
英語
|
論文のバージョン | publisher
|
査読 |
有り
|
PubMed ID | |
Web of Science KeyUT |