| ID | 34248 |
| フルテキストURL | |
| 著者 |
Kimura, Yoshinobu
Department of Biofunctional Chemistry, Division of Bioscience, Graduate School of Natural Science and Technology, Okayama University
Kaken ID
publons
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Sakamura, Sho
Department of Biofunctional Chemistry, Division of Bioscience, Graduate School of Natural Science and Technology, Okayama University
Ushijima, Takayuki
Department of Biofunctional Chemistry, Division of Bioscience, Graduate School of Natural Science and Technology, Okayama University
Hama, Yoichiro
Department of Applied Biological Sciences, Faculty of Agriculture, Saga University
Kajiura, Hiroyuki
The International Center for Biotechnology, Osaka University
Fujiyama, Kazuhito
The International Center for Biotechnology, Osaka University
Okihara, Kiyoshi
Yamada Apiculture Center, Inc.
Hashimoto, Ken
Yamada Apiculture Center, Inc.
Sugimoto, Hiroyuki
Yamada Apiculture Center, Inc.
Yamada, Hideo
Yamada Apiculture Center, Inc.
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| 抄録 | In a previous study (Y. Kimura et al., Biosci. Biotechnol Biochem., 70, 2583-2587, 2006), we found that new complex type N-glycans harboring Thomsen-Friedenreich antigen (Ga1 beta 1-3GalNAc) unit occur on royal jelly glycoproteins, suggesting the involvement of a new beta 1-3galactosyltransferase in the synthesis of the unusual complex type N-glycans. So far, such beta 1-3galactosyltransferase activity, which can transfer galactosyl residues with the beta 1-3 linkage to beta 1-4 GalNAc residues in N-glycan, has not been found among any eucaryotic cells. But using GalNAc(2)GlcNAc(2)Man(3)-GlcNAc(2)-PA as acceptor N-glycan, we detected the beta 1-3 galactosyltransferase activity in membrane fraction prepared from honeybee cephalic portions. This result indicates that honeybee expresses a unique beta 1-3 galactosyltransferase involved in biosynthesis of the unusual N-glycan containing a tumor related antigen in the hypopharyngeal gland.
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| キーワード | royal jelly glycoprotein; N-glycan
Thomsen-Friedenreich antigen (Gal beta 1-3GalNAc)
beta 1-3 galactosyltransferase
Apis mellifera
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| 備考 | Published with permission from the copyright holder.
This is published in Bioscience Biotechnology and Biochemistry, 2007 Vol.71 Issue.4 pp.1111-1114 Publisher URL: http://dx.doi.org/10.1271/bbb.70081 Direct access to Thomson Web of Science record (C)2008 by Japan Society for Bioscience, Biotechnology, and Agrochemistry |
| 発行日 | 2007-04
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| 出版物タイトル |
Bioscience, Biotechnology, and Biochemistry
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| 巻 | 71巻
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| 号 | 4号
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| 出版者 | Japan Society for Bioscience, Biotechnology, and Agrochemistry
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| 出版者（別表記） | 日本農芸化学会
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| 開始ページ | 1111
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| 終了ページ | 1114
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| ISSN | 0916-8451
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| NCID | AA10824164
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| 資料タイプ |
学術雑誌論文
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| 言語 |
英語
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| 著作権者 | Japan Society for Bioscience, Biotechnology and Agrochemistry
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| 論文のバージョン | publisher
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| 査読 |
有り
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| DOI | |
| Web of Science KeyUT | |
| Submission Path | biochemistry/18
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