Published by Misasa Medical Center, Okayama University Medical School
Published by Misasa Medical Center, Okayama University Medical School

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岡大三朝分院研究報告 (63号-72号) 環境病態研報告 (57号-62号)
岡山大学温泉研究所報告 (5号-56号) 放射能泉研究所報告 (1号-4号)

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House dust mite allergy in patients with bronchial asthma. Serum IgE levels and IgE antibody values in relation to patient age.

Tanizaki, Yoshiro
Kitani, Hikaru
Mifune, Takashi
Kajimoto, Kazuhiro
Sugimoto, Keisuke
Yokota, Satoshi
Hiramatsu, Junichi
Ochi, Koji
Harada, Hideo
Tada, Shinya
Kimura, Ikuro
Abstract
Serum IgE levels and IgE antibody values in relation to patient age were examined in 50 patients with house dust mite (HDm) sensitive asthma, 1. IgE antibody values to HDm were highest in patients between the ages of 10 and 19, and the values generally low in those over the age of 40. 2. High IgE antibody values to HDm were accompanied by high serum IgE levels in patients between 10 and 19. IgE antibody values and serum IgE levels were in general low in patients over age 40. In patient under age 9, serum IgE levels were less than 500 IU/ml in 5 of the 10 subjects despite an increased value of IgE antibodies to HDm. These results suggest that an increased production of IgE antibodies to HDm is usually accompanied by an increased production of total IgE in younger subjects. However, an increase in production of IgE antibodies is not always related to an increase in production of total IgE in patients under age 9. The results also show that production of IgE antibodies to HDm and total IgE is in general low in older patients despite the hyperreactivity to HDm.
Keywords
Serum IgE (血清IgE)
IgE antibodies (IgE抗体)
house dust mite (ダニ)
bronchial asthma (気管支喘息)
ISSN
0918-7839
NCID
AN10430852