Studies on the migration of basophilic leucocytes at the sites of allergic reactions Part I. Appearance of basophilic leucocytes at the sites of non-spesific inflamatory reactions

Vesicles induced by using Unguentum Vesicans at the sites of untreated or reactive skins to allergens of healthy individuals were investigated. Vesicles of patients with bronchial asthma were investigated only at the untreated skins. The numbers of basophilic and eosinophilic leucocyte in the exudate obtained from these vesicles were examined. The results were as follows. 1) The numbers of the total white cells in the exudate were found higher in the vesicular fluid of the patients with bronchial asthma than in that of the healthy individuals. 2) Larger numbers of basophils and eosinophils were found in vesicular fluid of the patients with bronchial asthma than in that of healthy individuals. And, the increase of these cells in numbers were conspicuously observed in the positive immediate-type skin reaction of the healthy individuals. 3) There was no relationship between the numbers of these cells in peripheral blood and in the vesicle.