Studies on supravital observation of basophils in bronchial asthma in immunological reaction Part Ⅰ. Changes of migration velocity of basophils by addition of anti-immunoglobulin

Changes of migration velocity of peripheral blood basophils by addition of anti-IgE or anti-IgG were observed in 13 asthma patients including 5 of high IgE asthma, 5 of low IgE asthma and 3 of buckwheat asthma cases. Basophils from high IgE asthma cases showed increased migration velocity by addition of anti-IgE. By addition of anti-IgG, however, the basophils ahowed no change in migration velocity. Basophils from low IgE intractable asthmatic patients showed increased migration velocity by addition of anti-IgG but not of anti-IgE. Buckwheat asthma cases showed the similar changes as in high IgE cases, when exposed to the antigen of buckwheat.