1) The distribution in the organs of Wister rats (female) was studied by making them inhale lead fume for four hours, the concentration of which was as high as 15.2 mg/m(3). 2) Immediately after inhaleling lead fume, the amount of distributed lead increased clearly in lung, liver and kidney, and slightly increased in spleen, bone marrow and bone, and after seven days amount in blood of inhaled rat came to the normal level. 3) It is inferred that kidney and bone are the organ where lead accumulates. 4) It was recognized that polychromatic red cells increased in the peripheral blood.